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Facile Synthesis Process, Characterization Study and Determination of Thermoluminescence Kinetic Parameters of Combustion-Synthesized Nano Phosphor for Dosimetry and Long Persistent Applications

DOI: 10.31038/NAMS.2023634

Abstract

In this section, we describe the facile urea-assisted combustion synthesis technique that was used to synthesis of the Dy3+ activated Ca2MgSi2O7 phosphor at the already maintained muffle furnace temperature 600°C. In addition, the characterization studies of the synthesized powder samples are well reported on the basis of their structural, morphological, elemental, and thermal analysis. The synthesized Ca2MgSi2O7:Dy3+ nanophosphor was further characterized by using XRD, FESEM, EDX, and, TL analysis. The obtained XRD pattern indicates tetragonal crystal structures that are compatible with JCPDS card number #79-2425 and recognizes the formation of the desired Ca2MgSi2O7 host without any traces of impurity for confirmation of phase purity. The average crystallite size was estimated using Debye-Scherer’s formula, and was found to be in the range of ~27 nm. It performed a FESEM study to demonstrate exterior morphology. EDX spectra have been employed to establish the sintered phosphor’s elemental composition. The acquired TL glow curve have used to determine the thermal characteristics of the as-synthesized phosphor. Dy3+ doped samples have exposed for 15 min to UV exposure show optimum TL intensity at 112.21°C. With alterations to UV exposure time, it also becomes apparent that the ambient temperature corresponding to the TL peak remains constant. In order to conduct further research on characteristics including activation energy, order of kinetics, and frequency factor, samples with 4 mol% of Dy3+ exposed for varied UV exposure times were chosen. All of these parameters were assessed using the peak shape method. The aforementioned results suggest that an alternative preference for thermoluminescence dosimetry (TLD) and long-lasting applications is the combustion-synthesized Dy3+-doped Ca2MgSi2O7 nanophosphor.

Keywords

Combustion, XRD, FESEM, EDX, Tetragonal, Thermoluminescence (TL), Ca2MgSi2O7:Dy3+

Introduction

Researchers and material scientists have lately been paying special attention to compounds of nanosized luminescent materials of the melilite group doped with rare earth (RE) ions. Alkaline earth silicate phosphors have excellent qualities like high quantum efficiency, abundance, resistance to weathering, affordability, and environmental features. Silicates were also thought to be one of the best host materials for luminescence centers due to their chemical and thermal stability and long persistence times [1]. The reduction of particle size can result in remarkable modifications of some of their bulk properties, nanosized phosphors usually exhibit novel capabilities, such as higher luminescent efficiency [2], and remarkable application potential. The melilites are a large group of compounds characterized by the general formula , where M is a large monovalent or divalent cation, T1 is a small divalent or trivalent cation in tetrahedral, T2 is also a small cation in the other tetrahedral and X is an anion. Afterglow in melilite has already been well documented [3]. In the field of luminescence, the potential utility of lanthanide ions as activators has recently become widely recognized [4]. The afterglow properties of phosphors can be tailored to last for a few seconds to several hours using various activators [5]. Dy3+ is a very effective luminescent centre when utilized as an activator, according to several experimental results of luminescence in some inorganic systems. Furthermore, Dy3+ doped Ca2MgSi2O7 phosphor has been extensively explored for its thermoluminescence properties as a long-lasting phosphor. The persistent emission appears stronger when Dy3+ is added to the host because it is very likely that these ions are involved in electron trapping. With regard to the ability of two Dy3+ ions to substitute for the three ions of the host, it’s possible that the Dy3+ ions will play a role in the creation of defects that act as oxygen vacancies or electron traps [6,7]. Properties like linearity, dose range, energy response, repeatability, stability of stored information, and isotropy are taken into consideration while evaluating the performance of TLD [8]. The preparation of TLDs had good chemical and moisture stability as a result of the addition of SiO2.xH2O and the prudent choice of the chemical form of activators. To analyze the trap centers and trap level in an insulator or semiconductor driven by any radiation-source, TL is one of the most effective techniques [9]. Traps produced by the lattice imperfections play a significant role in the TL characteristics of the phosphors [10].

Accordingly, traps play an essential role in TL research. Understanding the composition of charge carriers’ trapping states is also important. The trapped electrons release energy when heated because they move back to their normal, lower-energy positions. By comprehensively analyzing the TL glow curve, one can learn regarding the trap states and recombination centers [11]. Nowadays, TL materials are widely studied as an effective tool for various applications in the fields of material characterization, archaeological and geological dating, radiation dosimetry, biological applications, age determination, geology or solid-state defect structure analysis, personnel and environmental monitoring etc., being done. Therefore, we suggest that the sintered Dy3+ doped Ca2MgSi2O7 phosphor is a preferable long-persistent phosphor and novel TL material because rare earth dysprosium [Dy3+] ions mainly act as trap centers. In our present investigation, the TL intensity is highly dependent on the concentration of dopants (Dy3+) ions. The maximum intensity of Dy3+ ions was 4 mol% and TL intensity optimum for 15 min UV exposure radiation time and then TL intensity decreases with further UV exposure.

In this article, we have described the synthesis-characterization and thermoluminescence characteristics of prepared the calcium magnesium silicate phosphor (Ca2MgSi2O7:Dy3+) by combustion synthesis utilizing urea (NH2CONH2) as fuel and boric acid (H3BO3) used as flux. Equipped phosphors were characterized and investigated by using X-ray diffractometer (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX) analysis and Thermoluminescence (TL) analysis in order to structural, morphological, elemental composition, and thermal properties of synthesized powder samples. The aim of this paper is to present the kinetic parameters of the main glow peak (385.21 K) of Ca2MgSi2O7:Dy3+, which have important aspects in the general description of physical characteristics of TL materials, using peak shape (PS) method, namely the order of kinetics (b), symmetry factor (µg), activation energy E (in eV), the frequency factor S (in s−1).

Experimental Analysis

Combustion Synthesis

In order to meet the demands of Material Science and Engineering to create inorganic materials with the appropriate composition, structure, and property, combustion synthesis (CS) has been developed as a standard approach. To sustain a self-propagating high reaction temperature, CS employs extremely exothermic (∆H ≤ 170 kJ/mol) redox (reduction-oxidation) chemicals and combinations, as well as explosive reactions. Metal nitrates serve as the oxidant while urea serves as the fuel in the combustion process. Additionally, this method has the ability to enhance materials, save energy, and protect the environment [12]. The combustion process’ key benefits include rapid heating rates, better processing times, energy efficiency, and the capacity to yield superfine, homogenous, nanocrystalline powders from the combustion products. A vital component of the simple method without a requirement for an expensive high-temperature furnace is the implementation of the enthalpy of combustion to produce and crystallize powders at low calcination temperatures [13]. This technology can effectively replace time-consuming traditional solid-state reaction and sol-gel processing techniques [14]. Numerous refractory materials, such as borides, nitrides, oxides, silicides, intermetallic, and ceramics, have been prepared using this technique.

Powder Sample Preparation

Combustion technique (Figure 1) was successfully employed for the preparation of M2MgSi2O7: Dy3+ (M=Ca) nanophosphor. The starting materials used for the preparation were of Analar grade with high- purity (i.e. 99.99%) and include calcium nitrate [Ca (NO3)2.6H2O], magnesium nitrate [Mg (NO3)2.6H2O], dysprosium nitrate [Dy (NO3)3.5H2O], and fumed silica (SiO2.xH2O). All metal nitrates were considered as sources of oxidizers, boric acid [H3BO3] as flux, and urea [NH2-CO-NH2] was used as fuel. The stoichiometric quantities of the mixture were stirred thoroughly using a magnetic stirrer to obtain a clear solution. The resulting solution was placed in a preheated muffle furnace maintained at 600°C for 5 min. Initially, the solution was thermally dehydrated and later ignited with the liberation of large amount of gases (N2, O2, etc.). Once ignited, the combustion propagates on its own without the need of any external heat. The silicate in a foamy form was obtained finally.

FIG 1

Figure 1: Synthesization of Ca2MgSi2O7: Dy3+ nanometer powder using combustion synthesis technique

After the completion of the process, the product was grinded well using agate mortar pastel to convert into a fine powder form. Further, the sample was post-annealed at 900°C for 2 h under an air atmosphere. In order to obtain white powder, the sample was then despondent cooled to room temperature. The resulting sample was put back together in an airtight bottle for additional characterization investigations such XRD, FESEM, EDX, and TL analysis. Assuming total combustion of the redox mixture for the synthesis of Ca2MgSi2O7 could be written as:

Ca (NO3)2.6H2O + Mg (NO3)2.6H2O + SiO2.xH2O + NH2CONH2 + H3BO3 → Ca2MgSi2O7 + H2O (↑) + CO2 (↑) + N2 (↑)                   (1)

Ca (NO3)2.6H2O + Mg (NO3)2.6H2O + SiO2.xH2O + Dy (NO3)3.5H2O + NH2CONH2 + H3BO3 → Ca2 MgSi2O7: Dy3+ + H2O (↑) + CO2 (↑) + N2 (↑)                                           (2)

Powder Sample Characterization

Phase structure and composition of the synthesized samples remained categorized by X-ray diffraction arrangement using Bruker D8 advance X-ray diffractometer with Cu-Kα radiation having wavelength 1.5405 Å at 40 kV, and 40 mA. The XRD data were measured over a scattering angle range of 10° to 80°. The surface morphology and EDX analysis performed with the help of FESEM (ZEISS EVO Series EVO 18 microscope) fitted with EDX spectra. Thermoluminescence (TL) glow curves of the UV-irradiated (254 nm) samples were plotted between emitted TL intensity and the corresponding temperature using routine TL set-up Nucleonix TLD reader (1009I) with constant heating rate 5°Cs-1.

Fuel and Oxidizers

Fuel and oxidizers must be utilized during the combustion synthesis process. All metal nitrates are employed as oxidizers, together with boric acid (H3BO3) as a flux and urea (NH2CONH2) as a fuel for combustion. The stoichiometric proportions of all metal nitrates and fuel are calculated using the propellant’s chemistry. With the calculation of oxidizer to fuel ratio, the elements were assigned formal valences as follows: Ca=+2, Mg=+2, Dy=+3, Si=+4, B=+3, C=+4, H=+1, O=-2, and N=0 [15].

Oxidizer and Fuel Ratio

Determining the oxidant to fuel ratio is the most important phase since it is the deciding factor that affects the characteristics of the nanomaterials that will be created. The oxidizer to fuel ratio is termed as “Ψ”, which is defined as following relation [16].

3

This ratio is very crucial in determining parameters such as reaction temperature and numerous characteristics of nanosized materials such as electrochemical, crystallinity, phase purity and morphology. Additionally, it has been also observed that the particle size of nanomaterial is influenced by the oxidant-fuel ratio. Hence, the oxygen/fuel ratio at which the heat generated by combustion is maximum is 1 [17].

Effect of Fluxes

Some unique fluxes, including Li2CO3 (lithium carbonate), NH4F (ammonium fluoride), NH4Cl (ammonium chloride), BaF2 (barium fluoride), YF3 (Yttrium Fluoride), AlF3 (aluminum fluoride), H3BO3 (boric acid) [18], KCl (potassium chloride), LiF (lithium fluoride), CaCl2 (calcium chloride) [19] etc. are additionally included with the initial precursors to enhance the creation of crystal structures and the properties of the materials, speed up the reaction, and decrease the reaction temperature. The morphological properties of silicate materials are influenced by flux, which additionally enhances the luminous efficiency of powders. The potential benefits and rate of the reaction are influenced by the reactants’ structural characteristics and the reaction circumstances. Any nano- and micro-phosphors’ crystal structure development depends significantly on fluxes. Any formation moves along more quickly because to these fluxes. The final outcome is the synthesis of phosphors with actual chemical structures [20].

Results and Discussion

Powder X-Ray Diffraction Analysis (XRD)

An efficient, necessary, analytical, and nondestructive method for material characterization is powder X-ray diffraction analysis [21]. Diffraction is an X-ray-based technique that provides information on a unit cell’s chemical composition, phase structure, and crystallinity, as well as its microstructure, crystallinity, and stress analysis. It also provides data on its percentage phase composition, inter-planar spacing, and lattice parameters. Figure 1 shows the crystal phase of the phosphor. Comparison of the recorded XRD patterns with the standard JCPDS card number #79-2425 showed good agreement [22]. Akermanite-type structure describes the crystalline structures of synthesized phosphor, which is a member of the tetragonal crystal system with the cell parameters a=b=7.8071 Å, c=4.9821 Å; and α=90°, β=90°, γ=90°, as well as space group is P¯421m (113 space number and D32d space group) and point group is -42 m. Ca2MgSi2O7 crystal structure has a cell volume of 303.663 Å3 and a molar density of 2.944 gm/cm3 [7,23]. The XRD pattern (Figure 2) shows that the sample is single phased, which is consistent with JCPDS file no. 79-2425.

FIG 2

Figure 2: XRD patterns of host & Dy3+ activated Ca2MgSi2O7 phosphor

Estimation of Crystallite Size (D)

The XRD measurement displays a slight shift towards the larger angle in contrast to the standard reference data. From the XRD diffraction peaks, the crystallite size was determined with the help of the Debye-Scherrer empirical formula [24,25].

Debye-Scherrer numerical expression as follows:

4

where k is the Scherrer constant, D is the crystallite size for the (hkl) plane, 𝜆 is the wavelength of the incident X-ray radiation [Cu-Kα (1.5405 Å)], β is the full width at half maximum (FWHM) in radiations, and 𝜃 is the corresponding angle of Bragg diffraction. Based on the Debye-Scherrer’s formula, the average particle size obtained from the XRD measurement is ~27 nm, which displays in nano form.

Analysis of Surface Morphology (FESEM) Micrographs

The combustion-synthesized phosphor’s morphology at a 2-micron scale can be seen in the FESEM micrograph (Figure 3), which suggests that the synthesized crystal is in nano form. The particles’ highly agglomerated crystallite shape gives them a frothy appearance. The precursor particles had a spherical shape and were microscopic in size. It also shows aggregated grains, which might be a result of the powder’s extended stay within a combustion furnace. Throughout the combustion reaction process, the particles cluster and get larger. In present case, we have determined the mean value of particle size by Image J software about 20.492 nm.

FIG 3

Figure 3: FESEM morphological Image of Dy3+ activated Ca2MgSi2O7 Phosphor with 20.00 K X magnification

Despite the fact that a sample containing stoichiometric proportions of redox mixture boils, goes through dehydration, and then decomposes, creating combustible gases which involves oxides of N2, H2O, and nascent oxygen when heated fast to 600°C. The doped phosphor lattice is able to develop in the ideal environment, which forms when the volatile combustible gases ignite, burn with a flame, and ignite. In addition, this procedure makes it possible to uniformly (homogeneously) dope rare-earth impurity ions in one step. We also anticipate that the particle surface shape may have an impact on the thermal characteristics of these phosphor materials.

Figure 4 shows the electron Image of the synthesized Ca2MgSi2O7: Dy3+ phosphor. It is clearly evident from the picture that the dysprosium ions are well deep trapped in the host crystal lattice sites. That is, they are indicating deeper traps. Dy3+ ions served as hole traps (Dy3+ + hole → Dy4+). Between the lower energy state (ground) and higher energy state (excited) state, Dy3+ ions serve as deep hole trap levels. Dy3+ ions may trap holes or electrons or just to create/modify defects as a result of charge compensation. The deeper traps are highly responsible for the persistent luminescence.

FIG 4

Figure 4: Electron image of synthesized Ca2MgSi2O7: Dy3+ phosphor

Analysis of Energy Dispersive X-ray (EDX) Spectroscopy

Using EDX spectra, the chemical constituents of the powder sample has been determined. Identification and measurement of the elemental composition of sample areas as small as a few nanometers are conventional procedures [26]. In EDX spectra, the presence of Ca, Mg, Si, O and Dy intense peak are present which preliminary indicates the formation of Ca2MgSi2O7: Dy3+ phosphor in Figure 5.

FIG 5

Figure 5: EDX Spectrum of Dy3+ activated Ca2MgSi2O7 phosphor

As well as the existence of dysprosium is clear in their corresponding EDX spectra. Their appeared no other emission apart from calcium (Ca), magnesium (Mg), silicon (Si), oxygen (O), and dysprosium (Dy) in Ca2MgSi2O7: Dy3+ EDX spectra of the phosphor. The elements present in the Weight% and Atomic% also determined which is represented in Table 1.

Table 1: Chemical composition of synthesized Ca2MgSi2O7: Dy3+ phosphor

Sr.

Element

Weight%

Atomic%

1. O K

54.98

71.64

2. Mg K

6.57

5.63

3. Si K

13.98

10.38

4. Ca K

23.50

12.22

5. Dy L

0.97

0.12

6. Totals

100.00

100.00

Thermoluminescence (TL) Analysis

TL Spectra

When some of the energy needed to irradiate a material is used to move electrons to traps, a phenomenon referred to as thermoluminescence (TL). This energy, which was trapped as trapped electrons, is released when the material’s temperature rises, turning the luminescence that results into TL emission [27]. The thermo luminescence dosimetry (TLD) of ionizing radiation, thermo luminescence dosimetry (TLD) for dating applications, and also provides insights on the trap levels are all extensively employed features of the TL technique [28]. The basic goal of TL experiments is to acquire data from an experimental glow curve, or from a series of experimental glow curves, and to analyze that data in order to determine values for all of the parameters with regard to the relevant luminescence mechanisms.The single and strong TL glow curve of UV-irradiated Dy3+ (4 mol%) activated Ca2MgSi2O7 with constant heating rate (5°C/sec) at different UV radiation times (i.e. 5 min, 10 min, 15 min, 25 min, 25 min) is shown in Figure 6. Since the population of trapped electrons in a metastable state reaches a maximum value at a specific time, the TL intensity in this case increases with increasing irradiation time up to 15 min, then decreases with time. From the TL glow curve of Ca2MgSi2O7:Dy3+ it was observed that single broad fitted peak are centered at 112.21°C. The corresponding depth of the trap at 112.21°C should be deeper (high temperature). Deeper traps are highly helpful for increasing the long persistent duration and afterglow process [7]. Therefore, TL data reveal the presence of single trapping levels in Ca2MgSi2O7:Dy3+ phosphor.

FIG 6

Figure 6: TL glow curve of synthesized Ca2MgSi2O7:Dy3+ phosphor

Concentration Effect of Dy3+ ions

It is obvious that the TL intensity rises with rising Dy3+ concentration, reaches a maximum value at 4 mol%, and then falls with increasing Dy3+ ion concentration. The distance between the activators ions decreases as the activator concentration rises. The ions get involved more frequently, and energy is transferred. On the other hand, the energy that the ions store decreases as the activator concentration rises [7,26]. Consequently, there is an optimum concentration of the activator ions. As is seen from figure the favorable concentration of Dy3+ in Ca2MgSi2O7 nanophosphor is about 4 mole % (relative to Ca2+). The ionic radii of Ca2+, Mg2+, Si4+ and Dy3+ are 1.12 Å, 0.58 Å, 0.26 Å, and 0.97 Å, respectively [29]. When Dy3+ ions doped into Ca2MgSi2O7 host lattice, they may prefer to occupy the Ca2+ crystallographic site rather than Dy3+ site, because the radius of the Dy3+ is very closer to that of the Ca2+ lattice site [30]. A positive centre (hole) is formed when a trivalent metallic ion (such as Dy3+) substitutes a divalent metallic ion in a host lattice. So, Dy3+ ions hardly incorporate into tetrahedral [MgO4] and [SiO4] and only incorporate into [CaO8] anions complexes in host lattice [31]. The traps are released when the phosphor is heated, and the intensity of the thermoluminescence is raised by radiative recombination at the Dy3+ ions.

Peak Shape Method

The most significant glow curve peak’s kinetic parameters are found using the peak shape approach (Figure 7), also referred to as Chen’s empirical method [32]. The kinetic/trapping parameters such as the trap depth or activation energy (E), the order of the kinetics (b), and the frequency factor (s) have a significant impact on the TL characteristics. The area under the curve, the heating rate, the form of the glow curve, and other analytical techniques have all been developed to get TL parameters. The next sections provide a brief overview of the peak shape approach and the findings it produced for the current investigation.

FIG 7

Figure 7: An illustration of a typical thermoluminescent light curve utilizing the peak shape approach

Calculation of Kinetic/Trapping Parameters

[a] Order of kinetics (b)

Recombination of de-trapped charge carriers with their counterparts is referred to as the order of kinetics (b), and the order of kinetics depends on the TL peak shape approach. The TL glow peak of the Ca2MgSi2O7:Dy3+ phosphor TL glow curves was calculated using Chen’s empirical formula.

The geometrical factor μg was calculated as:

5

Here, Tm is the temperature corresponding of high peak intensity, whereas T1 and T2 is the ascending and descending part of peak correspond to the full-width at half maxima (FWHM). The TL glow peak divided between first and second order of kinetics of geometric factor defined, first order kinetics (μg)=0.39-0.42, (μg)=0.49-0.52 is the second order kinetics and (μg)=0.43-0.48 is the mixed order of kinetics [33].

The calculated symmetry factor (g) for the single peak was 0.47-0.51, which is close to the value for the second-order kinetics. This demonstrates that the single band’s peaks are of second order. The outcome shows that, in compared to the first-order example, the chance of retrapping carriers is higher after the carriers from the traps corresponding to the single bands were freed [34].

[b] Activation energy (E)

We used the following equation to estimate the depth of the traps, (E). It is calculated by the general formula, which is valid for any kinetics. It is given by,

6

For general order kinetics cα and bα (α=τ, δ, ω) are calculated by following expression,

6.123

[c] Frequency factor (S)

After being exposed to ionizing radiation, the frequency factor is a probability that indicates the escape of electrons from the traps. After determining the kinetics order (b) and activation energy (E), the frequency factor (s) has been determined from the following equation and the values of b and E were substituted.

7

Here, β is heating rate, k is Boltzmann constant, and b is the order of the kinetics, which is 2 in this case. The TL glow curves were recorded by TLD reader (Nucleonix Model 1009I)) with a linear heating rate of 5°C s−1 [35].

Table 2 shows the effects of various UV exposure times, such as 5, 10, 15, 20, and 25 minutes, on the Ca2MgSi2O7:Dy3+ phosphor and several TL kinetic parameters, such as trap energy, symmetry factor, and frequency factor.

Table 2: Values of different Kinetic parameters of the main TL glow peak curves of Ca2MgSi2O7:Dy3+ phosphor calculated from using peak shape method.

UV Radiation Time

(oC)

(oC)

(oC)

E (eV)

Frequency Factor

5 min

86.43

112.21

139.36

25.78

27.15

52.93

0.51

0.72

1.2 × 107

10 min

87.33

112.21

136.10

24.88

23.89

48.77

0.49

0.77

2.87 × 107

15 min

87.33

112.21

136.10

24.88

23.89

48.77

0.49

0.77

2.87 × 107

20 min

85.69

112.21

139.36

26.52

27.15

53.67

0.51

0.71

1.2 × 107

25 min

85.69

112.21

136.10

26.52

23.89

50.41

0.47

0.66

1.1 × 107

This method was applied to the cleaned main peak determined by means of trap energy (E), frequency factor (s) and symmetry factor (μg) were calculated using Eqs. (5) and (6). Symmetry factor (μg), average trap energy and frequency factor were found between in the range of 0.47-0.51, 0.66-0.77 eV and 1.1 × 107 to 2.87 × 107 s−1, respectively. Thus, in our case, we obtained the maximum thermo-luminescence [TL] in 15 min UV exposures time. In our case, symmetry factor (μg) is lies between 0.47-0.51, which signs that it is a case of second order kinetics, responsible for deeper trap depth. According to Sakai’s and Mashangva report, he is also reported that a trap depth between 0.65-0.75 eV is very appropriate for long afterglow properties [36,37].

It is obvious that the dysprosium ion, because of its inherent nature, is more to responsible for the hole trap level. That is, the dysprosium ion’s inherent properties enable it to produce a hole trap level as soon as it reaches the host crystal lattice. In a host lattice site, these hole trap levels are trapped extremely deeply. The material has long-lasting properties as a result of these deeper traps.

Conclusion

Tetragonal samples of Ca2 MgSi2O7 with 4 mol% dopant concentration of Dy3+ ions have been successfully synthesized by combustion synthesis technique method at 600°C, which appears to be the most feasible method for their production. For better understanding its spectroscopic and luminescent characteristics, several characterization approaches were investigated. Amorphous structure and nanoscale particle size were determined using XRD and FESEM analyses. The crystallite particle size has been calculated as 27 nm and 20.492 nm. The size of the crystallites has been achieved in the nano order and nano range with considerably greater uniformity. The surface morphology of the particles is shown by the FESEM data to have a flake-like structure, a uniform, homogenous, superfine crystal structure, and to have aggregated firmly. The EDX spectra confirmed the presence of Ca, Mg, Si, O and Dy elements in Ca2 MgSi2O7:Dy3+ phosphor. The TL glow curves are centered at 112.21°C for 15 min UV exposure time, which displays optimum UV exposure time. TL study shows that the optimum Dy3+ concentration was found for 4 mol%. The probability of recapturing released charge carriers before recombination is supported by the second order kinetics. The long after glow process is being enhanced considerably by Dy3+ ions. The activation energy of Ca2 MgSi2O7:Dy3+ was found to be 0.66-0.77 eV. On the basis of the value of the activation energy, we have suggested that the Combustion-synthesized Ca2MgSi2O7:Eu2+, Dy3+ phosphor is an excellent thermoluminescent material and a more efficient long persistent material. It may highly applicable for TL dosimetry and long persistent applications.

Future Scope of This Work

The advancement of energy-efficient transmission, storage, and generating technologies using nanomaterials has significantly enhanced the effectiveness of both conventional and renewable energy sources. The thermoluminescence properties of nanomaterials have highly applicable in archeological dating, forensic science, geology, medical dosimetry, environmental radiation, oncology radiation, biological science, radiation physics, medicine, neutron-dosimetry, UV radiation monitoring, high-level photon dosimetry radiation. Radiation therapy or radio-therapy have used in a cancer disease treatment and kill cancer cells. As-synthesized Ca2MgSi2O7: Dy3+ phosphor is an excellent thermoluminescent material and a more efficient long persistent material.

It is highly applicable in TL radiation dosimetry applications for personnel and environmental monitoring. The luminescent features of biomaterials have prospective applications in different areas such as DNA transplantation of tumor in the field of biological science, signal processing or image recognition in the field of computer science and information technology, drug delivery in the field of pharmaceutical science, and in the field of nutrition therapy, chemotherapy, as well as in the field of tissue engineering and bone-tissue engineering.

Acknowledgement

We gratefully acknowledge the kind support for the facility of XRD, FESEM, and EDX analysis Dept. of Metallurgical Engineering, NIT Raipur (C.G.). Authors are also thankful to Dept of physics, Pt. Ravishankar Shukla University, Raipur (C.G.) for providing us the facility of thermoluminescence (TL) analysis. We are also heartily grateful to Dept. of physics, Dr. Radha Bai, Govt. Navin Girls College Mathpara Raipur (C.G.), providing the facility of muffle furnace and other essential research instruments

Competing Interests

Authors have declared that no competing interests exist in this present research investigation.

Authors Contribution

Both authors contributed to the completion of this work. Author Dr. Shashank Sharma undertakes the manuscript designed and conducted the entire experiments and characterization studies, collected and analyzed the research data, and prepared the entire manuscript draft as well as supervised the results-discussion. Similarly, author Dr. Sanjay Kumar Dubey has properly checked the spelling mistake, punctuation, grammatical error, conceptualization, writing, review, editing and helped in sample preparation. Both authors read and approved the final manuscript.

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Synthesis of Nano-Gold Particles for Multi-functional Finishing of Cotton Fabrics

DOI: 10.31038/NAMS.2023633

Abstract

Gold nanoparticles (AuNPs) were synthesized in situ on cotton, one of the most popular cellulose materials, to achieve functionalization. The localized surface plasmon resonance of the AuNPs imparted the cotton fabric with colors, showing good colorfastness to washing and rubbing. Characterization of the surface morphology and chemical composition of the modified cotton fabric confirmed synthesis and coating of the AuNPs on cotton fibers. The relationship between the morphology of the AuNPs and the optical properties of the cotton fabric was analyzed. Acid condition enabled in situ synthesis of AuNPs on cotton. Cotton with AuNPs exhibited significant catalytic activity for reduction of 4-nitrophenol by sodium borohydride, and could be reused in this reaction. Treatment with AuNPs substantially improved the ultraviolet (UV)-blocking ability of the fabric and resulted in cotton with remarkable antibacterial activity. Traditional reactive dyes were applied to the cotton with AuNPs to enhance its color features. The catalytic properties of the AuNPs on the fabric were not influenced by dyeing with traditional dyes. AuNP-treated cotton fabric used as a flexible active substrate showed improved Raman signals of dyes on the fabric.

Keywords

Gold nanoparticles, Cotton, Coloration, Catalysis, Surface-enhanced Raman Scattering, Antibacterial

Introduction

Modification of cellulose fibers, in particular cotton products, using functional nanomaterials has attracted extensive attention, with the aim of imparting properties such as antibacterial, flame retardancy, and hydrophobic properties [1-7]. Many strategies have been developed to obtain such combinations of fabric and nanoparticles, including plasma treatment, electrostatic assembly, chelation by active groups, and in situ synthesis [8-12]. Anisotropic silver nanoparticles (AgNPs) have been assembled on cotton fabric via electrostatic interaction between nanoparticles and cotton fibers, endowing the textile with bright colors due to their unique optical property, i.e., localized surface plasmon resonance (LSPR) [13]. Cotton fabric with AgNPs was also modified, followed by treatment with fluorinated decyl polyhedral oligomeric silsesquioxane (FPOSS), to fabricate colored fabric with durable antibacterial and self-healing superhydrophobic properties. AgNPs have been combined with cotton under the binding effect of branched poly(ethylenimine) (PEI) [13]. Poly-butylacrylategrafted carbon nanotubes has been applied to cotton fabric using a common dipping–drying–curing finishing procedure [14]. The modified cotton showed various functions, such as enhanced mechanical properties and extraordinary flame retardancy. Core–shell-structured silica dioxide@zinc oxide (SiO2@ZnO) nanoparticles have been prepared and adhered to cotton fabric with the assistance of (3-Aminopropyl)triethoxysilane (APTES) or vinyltriethoxysilane (VTES) [15], resulting in textiles with antibacterial activity, UVprotection properties, and high durability. Titanium dioxide (TiO2) nanoparticles have also been used for functionalization of cotton to obtain fabric with selfcleaning and UV-blocking properties [16,17]. Among functional nanoparticles, gold nanoparticles (AuNPs) have received considerable attention from researchers, owing to their promising optical, electronic, magnetic, catalytic, and biomedical applications [18,19]. As the most stable metal nanoparticles, AuNPs can be prepared using straightforward routes and are resistant to oxidation, facilitating diverse applications. AuNPs present significant catalytic activity in various reaction systems. They exhibit unique optoelectronic features and possess excellent biocompatibility with appropriate ligands as well as high surface-to-volume ratio. The properties of AuNPs including the LSPR optical effect can be readily tuned by controlling their size, shape, and surroundings. Moreover, AuNPs have been widely used as effective active substrate materials for surface-enhanced Raman scattering (SERS) analysis. The Raman signals of molecules adsorbed on AuNPs can be extremely enhanced. Modification of textile materials with AuNPs can transfer some of these important properties to the resulting textile products. Cotton is the most widely used natural fibrous material for textile and clothing production. Modification of cotton is driven by growing consumer demand for enhanced functions of conventional textile products. In situ synthesis of nanoparticles on fabric/fibers is a simple and effective route to achieve functional modification of textile materials; For example, A hydrophobic hierarchical structure has been fabricated on cotton fabric by in situ growth of silica nanoparticles [20,21]. AgNPshas been synthesized in situ on cotton fabric by adjusting the pH value at room temperature. The as-synthesized AgNPs imparted vivid colors and strong antibacterial properties to the treated fabric. TiO2 nanoparticles have been synthesized with anatase structure using ultrasonic irradiation at low temperature and loaded them onto cotton fabric [22]. The TiO2-loaded cotton fabric exhibited UV-protection and self-cleaning features. ZnO nanoparticles have been synthesized in situ in the cellulosic pores of cotton fabric by reacting zinc nitrate and sodium hydroxide to obtain fabric with antibacterial and UV-protection properties [23]. In the previous research, AuNPs were synthesized in situ on silk fabric by heat treatment [24]. This silk fabric treated with AuNPs showed not only vivid colors but also enhanced Raman signals for use as an active SERS substrate for detection of trace analytes [25]. These results inspired us to develop cotton functionalized with AuNPs by in situ synthesis. In this study, cotton fabric was modified by AuNPs synthesized in situ through heat treatment. The optical properties of the resulting colorful fabric treated with AuNPs were analyzed based on color strength (K/S) curves and ultraviolet–visible (UV–Vis) diffuse reflectance absorption spectroscopy. The surface morphology of the cotton fabric before and after modification with AuNPs was investigated by scanning electron microscopy (SEM). The influence of pH on the in situ synthesis of the AuNPs was investigated. The catalytic activity and antibacterial features of the AuNP-treated cotton fabric were evaluated. Complex coloration of cotton fabric using both AuNPs and traditional dyes was also explored. Furthermore, cotton fabric with AuNPs was used as a flexible active substrate to enhance the Raman signals of dyes on the fabric.

Technical Details

The following chemicals were used
Tetrachloroauric(III) acid trihydrate, acetic acid, sodium hydroxide, 4-nitrophenol, and sodium borohydride, Cellulose powder, CI Reactive Red 3 and CI Reactive Red 195
The textile material used was Knitted cotton fabric
The instruments used for measurement are as follows
SEM
Plasma atomic emission spectrometer
Raman microscope system
Color i7 spectrophotometer
Liquor to fabric ratio was 50: 1
The following have been followed
Colorfastness to washing
Colorfastness to rubbing
Catalytic activity
Antibacterial testing against Gram negative bacterium (Figure 1)

FIG 1

Figure 1: Modification of cellulose fibers

Preparation and Characterization of Gold Nano-particles

Figure 2 shows a photograph of the treated cotton fabric samples. The cotton fabric treated in 0.025 mM HAuCl4 solution (Cot-Au-1) was light red, implying presence of AuNPs on the cotton fibers. The color of the cotton fabric with AuNPs changed from light red to red to dark red as the initial concentration of HAuCl4 was increased from 0.025 mM to 0.125 mM. Based on ICP-AES, the gold content of the cotton fabric with AuNPs was measured to be 0.386, 0.725, 0.921, 1.638, and 1.849 mg g-1 for Cot-Au-1, Cot-Au-2, Cot-Au-3, Cot-Au-4, and Cot-Au-5, respectively.

FIG 2

Figure 2: Treated cotton fabrics

The gold content of the samples increased as the concentration of HAuCl4 was increased. K/S curves were obtained to analyze the color changes. The peak of the K/ S curves for the treated cotton fabric remained unchanged, being located at 540 nm, with increasing gold content. However, the maximum value of the treated cotton fabric increased as the gold content was increased, consistent with its deepening color. UV– Vis diffuse reflectance absorption spectra of cotton fabric treated with AuNPs were measured. As shown in Figure 1c, a single absorption band located at 534 nm appeared in the UV–Vis absorption spectrum of CotAu-1, assigned to the characteristic LSPR mode of AuNPs. The LSPR band of cotton fabric treated with AuNPs red-shifted from 534 nm to 547 nm as the initial concentration of HAuCl4 was increased from 0.025 mM to 0.125 mM, along with an increase in the absorption band intensity. These changes in the color and LSPR property of the AuNP-treated cotton fabric may be related to the gold content, and the morphology and density of AuNPs on the cotton. SEM was employed to observe the surface morphology of the treated cotton fabric (Figure 3).

FIG 3

Figure 3: SEM images of a Cot-Au-1, b Cot-Au-2, c Cot-Au-3, d Cot-Au-4, and e Cot-Au-5

A number of nanoparticles were seen over the surface of fibers (Figure 2), demonstrating that AuNPs were synthesized in situ on the cotton. The size of the AuNPs on cotton was measured to be 8.7 ± 1.2, 8.6 ± 1.3, 14.1 ± 3.0, 17.4 ± 3.0, and 20.5 ± 3.8 nm for Cot-Au-1 to CotAu-5, respectively. Although the sizes for Cot-Au-1 and Cot-Au-2 were similar, Cot-Au-2 with higher LSPR intensity had higher density of AuNPs on fiber surfaces in comparison with Cot-Au-1. The size of AuNPs increased as the gold content of the samples increased as the Au ion concentration was changed from 0.05 mM to 0.125 mM. It was found that nearly all the nanoparticles on the cotton fibers were spherical for low gold content (Cot-Au-1, Cot-Au-2, and CotAu-3), whereas a few anisotropic AuNPs, such as triangular nanoplates, appeared when the gold content was increased to high level (Cot-Au-4 and Cot-Au-5). The anisotropy of the AuNPs led to the red-shift of the LSPR band observed in the UV– Vis diffuse reflectance absorption spectra of the AuNPtreated cotton fabric. As seen from the SEM images, the density of AuNPs reduced when the Au ion concentration was changed from 0.075 to 0.10 and 0.125 mM, due to generation of larger and anisotropic AuNPs. All these effects on the morphology (shape and size) and density of the AuNPs on cotton led to the changes in the LSPR property of the different samples. XPS was used to analyze the cotton fabric treated with AuNPs. XPS peaks assigned to O 1s and C 1s as the normal components of cellulose were seen in the XPS spectrum of Pri-Cot fabric. XPS peaks ascribed to Au element appeared in the XPS spectra after the cotton fabric was treated. The XPS spectrum for Cot-Au-4 displayed two principal bands at 82.2 and 85.8 eV, attributed to binding energies of 4f7/2 and 4f5/2 of metallic Au, respectively [26]. These XPS results indicate that AuNPs were successfully synthesized on the cotton fabric.

Influence of pH Value

We investigated the influence of the pH value on the in situ synthesis of AuNPs on the cotton fabric. The original pH value of the HAuCl4 aqueous solutions at 0.025–0.125 mM was around 4. The pH value of the reaction systems was adjusted by addition of acetic acid or NaOH aqueous solutions. The K/S curves and UV–Vis diffuse reflectance absorption spectra of cotton fabric treated has been obtained with 0.10 mM HAuCl4 solution at different pH values (3–6). As can be seen, the cotton fabric treated at pH 3 showed the highest K/S value of 1.71 among the different cotton samples. The K/S value of the AuNP-treated cotton fabric decreased as the pH value of the reaction system was increased. The maximum K/S decreased to 0.28 when the pH value was increased to 6. Vivid cotton fabric was obtained when using 0.10 mM HAuCl4 in the pH range of 3–6, although the cotton fabric changed slightly in color after heat treatment in HAuCl4 solution (0.10 mM) at pH 7 or above, implying that nearly no AuNPs were produced. The UV–Vis diffuse reflectance absorption bands of the cotton fabric treated with AuNPs at different pH values were centeredaround 540 nm. The intensity of the absorption bands decreased with increase in the pH value, consistent with the change trend of the K/S values. It can be inferred that acid condition facilitated in situ synthesis of AuNPs on cotton fabric, similar to the case of in situ preparation of AuNPs on ramie fibers [27]. It is well documented in literature that the pH value of the reaction system plays a vital role in formation of AuNPs through reduction of HAuCl4 [28-33]. Au ion complexes with chloride and/or hydroxide as ligands were suggested to be AuCl4 – (pH 3.3), AuCl3(OH)- (pH 6.2), AuCl2(OH)2 – (pH 7.1), AuCl(OH)3 – (pH 8.1), and Au(OH)4 – (pH 12.9) ions, corresponding to different ranges of pH [34,35]. The reduction potential of Au ion complexes depends remarkably on the pH value, with decreased reactivity as the pH is increased, in the order AuCl4 -[AuCl3(OH)-[AuCl2(OH)2 -[AuCl(OH)3 – [Au(OH)4 -. In the present study, AuNPs were synthesized in presence of cotton under acid condition, whereas Au ions were not reduced to form AuNPs in neutral or basic solution. The present results are consistent with previous analyses of the influence of pH on the formation of AuNPs. Mechanism of in situ synthesis of AuNPs It is well known that cellulose is the dominant component of cotton, consisting of long chains of Dglucose units [36]. In situ synthesis of AuNPs on cotton fabric in this study could result from reduction of Au ions by cellulose. Pure cellulose powder has been employed to reduce Au ions according to the same experimental procedure with cotton fabric. As shown in Figure S3, purplish red and grayish purple cellulose powders were produced after heat treatment in HAuCl4 solution, implying synthesis of AuNPs by cellulose. This result indicates that the reducing effect of cellulose in cotton led to in situ formation of AuNPs. Cellulose materials have been reported to act as reducing agents to synthesize AuNPs and AgNPs, owing to their abundant hydroxyl groups [37,38]. It is suggested that hydroxyl groups of cellulose play a pivotal role in the in situ formation of metal nanoparticles. The primary hydroxyl groups with higher reactivity in cellulose could be oxidized by Au ions during in situ synthesis of AuNPs. The reducing ends of cellulose in cotton could also contribute to reduction of Au ions to form AuNPs [39]. As proposed in previous research, oxygen-containing groups on the surface of cotton, including carboxylate and hydroxyl groups, can serve as active sites that might combine with AuNPs through complexing or electrostatic interaction [40]. Zeta potential measurements in our previous work indicated that cotton powder carries negative charge. It is suggested that a complexing or electrostatic interaction could lead to effective combination of synthesized AuNPs with cotton fabric in the present study. Cotton acted as a reducing agent and a stabilizing agent to prepare AuNPs on the fiber surface. Assessment of colorfastness is one of the important parameters to assess the properties and performance of textile products. The colorfastness to washing of the cotton fabric treated with AuNPs was tested by washing in presence of ECE reference detergent at 50oC for 45 min in each washing cycle. The DE values of the treated fabric before and after washing have been determined. After the first washing cycle, the DE values were measured to be 0.7 and 2.6 for Cot-Au-4 and Cot Au-5, respectively, revealing that color fading occurred for the cotton fabric treated with AuNPs during washing. However, the DE of the treated fabric increased slightly after the third washing cycle. These results demonstrate that the cotton fabric colored with AuNPs exhibited reasonably good colorfastness to washing. In addition, the colorfastness to rubbing of the treated cotton fabric was tested. The gray scale rating for the DE values of Cot-Au-2, Cot-Au-4, and Cot-Au-5 under dry and wet rubbing conditions was assessed. The dry rubbing colorfastness was rated as 5, 4–5, and 4–5 for Cot-Au-2, Cot-Au-4, and Cot-Au-5, respectively. The rating of the wet colorfastness of Cot-Au-2, Cot-Au-4, and Cot-Au-5 was estimated to be 4–5, 4, and 4, respectively. These results show that the cotton fabric treated with AuNPs exhibited good colorfastness to dry or wet rubbing. Investigation of catalytic activity AuNPs have been widely used as catalysts for various reactions [41-43]. In the present research, AuNPs were bound to cotton fibers after in situ synthesis. As the cotton fabric acts as a support for the nanoparticles (Scheme 1), they can be readily separated from the reaction system, enabling reuse of the catalyst. Reduction of 4-NP has been commonly used as a model catalytic reaction to evaluate the catalytic activity of metal nanoparticles [44]. The catalytic activity of the cotton fabric treated with AuNPs was assessed by monitoring the UV–Vis absorption spectra of aqueous solution during reduction of 4-NP using NaBH4. The color of the 4-NP solution changed from light yellow to green–yellow after addition of NaBH4. Nitro compounds are inert to NaBH4 in absence of catalyst, whereas metal nanoparticles can act as an electronic relay agent for electron transfer from NaBH4 to nitro compounds to accelerate the reduction reaction [45]. A new UV–Vis absorption peak for 4-NP solution appeared at 400 nm after NaBH4 was added, due to formation of 4-nitrophenolate ions. The evolution of the UV–Vis absorption spectra of 4-NP solution after mixture with NaBH4 in presence of pristine cotton fabric was recorded. The intensity of the absorption peak at 400 nm for 4-NP decreased only slightly, revealing that pristine cotton fabric showed no catalytic activity. Time-resolved UV–Vis absorption spectra of 4-NP solution with NaBH4 in presence of AuNP-treated cotton fabric have been obtained (Cot-Au-1 to Cot-Au-5). The absorption peak at 400 nm of 4-NP solution decreased distinctly in intensity after addition of NaBH4 in presence of all the fabric samples treated with AuNPs. Meanwhile, a new absorption peak arose at 300 nm due to the reduction process of 4-NP, implying formation of 4-AP [46,47]. The intensity of the absorption peak at 400 nm was plotted as a function of time to determine the reduction rate of 4-NP. The rapid intensity decrease of the peak at 400 nm indicates that the cotton fabric treated with AuNPs exhibited notable catalytic activity. It was found that the reduction system with Cot-Au-4 exhibited the highest reaction rate among the AuNPtreated cotton fabric samples. Reduction of 4-NP is generally considered to be a pseudo-first-order kinetic reaction on account of excess NaBH4 [48,49]. Plots of ln(At/A0) versus time have been obtained, where At and A0 denote the absorption intensity at 400 nm at time t and the initial stage, respectively. The linear correlation between ln(At/A0) and time confirms this pseudo-first-order hypothesis. The apparent rate constant (Kapp) of the catalytic reaction can be estimated from the linear slope of ln(At/A0) versus time. The Kapp value of the reduction reaction was found to be 1.89 9 10-2, 1.76 9 10-2, 2.29 9 10-2, 4.32 9 10-2, and 2.55 9 10-2 min-1 with Cot-Au-1, Cot-Au-2, CotAu-3, Cot-Au-4, and Cot-Au-5, respectively. The Kapp values obtained in this study are comparable to related literature results for AuNPs [50,51]. Comparing these Kapp values for the AuNP cotton fabric samples, CotAu-4 with the largest Kapp value showed the highest catalytic activity, although the gold content of CotAu-4 was lower than that of Cot-Au-5. The catalytic properties of the treated cotton fabric depend on the AuNPs on the surface of cotton fibers. It is believed that the catalytic activity is related to the shape, size, and density of AuNPs on the fabric. To evaluate the reusability of the catalyst, treated cotton fabric (CotAu-4) was separated from the reaction system and reused in repeated reduction reactions of 4-NP. The peak intensity at 400 nm versus reaction time for each complete conversion is plotted in Figure 6h. The treated fabric still exhibited strong catalytic activity even after seven cycles, indicating that the treated cotton fabric exhibited durable catalytic effect. UV-protection and antibacterial properties Treatment with AuNPs endowed the cotton fabric with additional functions. The UV transmittance and UV protection factor (UPF) values of the different fabric samples have been determined. Coating with AuNPs reduced the average transmittance values of the cotton fabric. Transmittance values in both the UVA (315–400 nm) and UVB (280–315 nm) regions showed a decreasing trend with increasing gold content on the cotton fabric. The UPF value of pristine cotton fabric was measured to be 65.1, while in situ synthesis of AuNPs on the cotton fabric increased the UPF value to 109.3, suggesting that the AuNPs improved the UV-blocking ability of the cotton fabric. The antibacterial properties of AuNPs have attracted great interest, and various potential antibacterial applications have been explored [52-54]. The antibacterial activity of cotton fabric treated with AuNPs was evaluated against Gram-negative bacterium E. Coli. The bacteria on the pristine cotton fabric and treated cotton fabric have been studied (CotAu-4). A full lawn of bacteria was seen on the plates corresponding to the pristine cotton fabric, whereas no bacteria colonies were found on the agar medium of the AuNP-treated cotton fabric, revealing that presence of AuNPs on the fabric inhibited growth of bacteria. These results demonstrate that the cotton fabric with AuNPs possessed significant antibacterial activity. Dyeing of AuNP-treated cotton fabric with traditional dyes to improve the color range and saturation of the fabric, traditional dyes including R3 and R195 were used to dye the AuNP-treated cotton fabric. Dyeing with traditional dyes imparted deeper color to the cotton fabric than that achieved based on the LSPR optical effect of the AuNPs. The K/S values of the cotton fabric observably increased after dyeing with R3 and R195. Due to the light color of AuNPs at low gold content (0.386 mg g-1), the K/ S curves of Cot-R3 were almost the same as for CotAu-R3-1. The K/S curves of Cot-R195 and Cot-Au-R195-1 were also the same. However, coating with more AuNPs gave rise to higher K/S values for the cotton fabric colored with AuNPs and traditional dyes (R3 and R195). The AuNPs and dyes played a combined role in the color of the cotton fabric, even though the traditional dyes dominated the optical properties of the colored cotton fabric. Coloration using traditional dyes did not influence the catalytic properties of the cotton fabric with AuNPs. The UV–Vis adsorption spectra of 4-NP solution with Cot-R195 changed very little after addition of NaBH4, demonstrating no evident catalytic activity of Cot-R195, consistent with the case of PriCot. The intensity of the UV–Vis absorption band at 400 nm of 4-NP solution in presence of Cot-Au-R195-4 decreased sharply after NaBH4 addition, revealing that the cotton fabric after complex coloration with AuNPs and traditional dyes retained strong catalytic activity. Moreover, the cotton fabric with AuNPs and R195 could be reused in the catalytic reaction, showing significant catalytic activity after seven cycles. These results attest that the catalytic properties of AuNPs on cotton fabric are retained after coloration with traditional dyes. SERS enhancement by AuNP-treated cotton fabric AuNPs have been widely used as active substrates for enhancing Raman signals due to their LSPR effect. Raman scattering spectra were obtained to investigate the SERS enhancement effect of the AuNP-treated cotton fabric. No distinct bands were seen in the Raman scattering spectrum of pristine cotton fabric. However, visible bands were found in the Raman scattering spectra after AuNPs were coated on the cotton fabric. Evident vibrational bands were seen at 1604, 1378, 1121, 1096, 519, 457, 435, 380, and 257 cm-1 in the Raman scattering spectra of the AuNP-treated cotton fabric, being characteristic Raman bands of cotton fibers [55,56]. Some of these bands are assigned to vibrations of b-1,4-glycosidic ring linkages between D-glucose units in cellulose. It was found that CotAu-5 exhibited the strongest Raman signal of cellulose among the AuNP-treated cotton fabric samples, which may be due to the optimal morphology and corresponding LSPR effect of the nanoparticles. Noble-metal nanoparticles on textiles can enhance the Raman signals of dyes used for coloration of fibers, leading to promising applications of SERS in the field of identification of cultural heritage, forensic analysis, and textile dyeing [57-61]. In the present study, we investigated the SERS enhancement of R3 on the AuNP-treated cotton fabric. The cotton fabric dyed with R3 without AuNPs showed unclear Raman bands from cellulose units and dye on the fabric. However, enhanced Raman bands were obtained from R3-dyed cotton fabric treated with AuNPs. The R3-dyed cotton fabric with higher gold content (Cot-Au-R3-4 and Cot-Au-R3-5) showed unambiguous enhanced Raman bands. The Raman scattering spectrum of pure R3 powder has been determined. Compared with the normal Raman scattering spectrum of R3, the SERS bands from Cot-Au-R3-4 and Cot-Au-R3-5 at 284, 385, 478, 1000, 1032, 1123, 1274, 1473, and 1589 cm-1 can be ascribed to R3 dye on the AuNP-treated cotton fabric, although tiny wavenumber shifts occurred due to interactions of the dye and cotton fibers as well as AuNPs. The AuNPs on the fabric enhanced the Raman signal of the dye on the fibers, facilitating nondestructive analysis of dyes on textiles and providing insights into the dyeing mechanism of fibers.

Conclusions

Cotton fabric was functionalized by AuNPs synthesized in situ by a heating method. The fabric was colored by the AuNPs by virtue of their LSPR optical effect. The intensity of the LSPR band of AuNPtreated fabric increased with increasing gold content in the cotton samples. The treated fabric showed good colorfastness to washing and rubbing. SEM and XPS investigations confirmed the synthesis and combination of AuNPs on cotton. The mechanism for in situ synthesis of AuNPs on cotton was investigated. The fabric with AuNPs exhibited notable catalytic activity, as shown by monitoring reduction of 4-NP to 4-AP. The cotton fabric with AuNPs showed improved UVprotection and excellent antibacterial properties. Traditional dyes were combined with the AuNP-treated cotton, revealing improved color properties. The fabric with such complex coloration still exhibited prominent catalytic activity. Cotton fabric with AuNPs can also act as a SERS substrate for analysis of dyes on the fabric.

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On the Modelling of Heat Conduction in Crystals via Higher-grade Terms

DOI: 10.31038/NAMS.2023632

Abstract

The paper investigates models expressed by equations with higher-grade spatial derivatives which are devised for describing transport phenomena in nanosystems. Particular attention is addressed to the Guyer-Krumhansl equation as a prototype of equations with higher-grade terms. First the thermodynamic consistency of the equation is investigated and conclusions are found for appropriate properties of the coefficients. Next a rather new approach is developed in that evolution equations are not given from the outset but are determined by applying a representation formula that makes the consequences of the second law directly operative. In this approach the free energy, the entropy flux, and the entropy production are considered as constitutive functions that eventually generate the desired evolution equation. Some equations derived in this way prove to be highly non-linear. The approach though leads also to simple models such as the one expressedby the well-known Maxwell-Cattaneo equation.

Keywords

Heat conduction in nanosystems, Higher-grade derivatives, Non-local equations, Guyer-Krumhansl equation

Introduction

In nanoscale systems the heat carrier mean free path may result comparable with the geometric dimensions. While equilibrium properties are well established within statistical mechanics [1], the order of dimensions explains why the literature shows a deep attention to heat transport equations of non-local character at the macroscopic level (see, e.g. [2-4]). Among the approaches involved in the derivation of macroscopic equations it is worth mentioning the recourse to the Boltzmann equation [5], phonon hydrodynamics models [6] or arguments within non-equilibrium thermodynamics [7]. The thermal properties of crystals at low temperatures is often modelled by the Guyer-Krumhansl equations for heat conduction [8]. For definiteness, in the uncoupled harmonic limit the equation for the heat flux reads

1

where the superposed dot is the time derivative and ∇ is the gradient operator. Within continuum physics, eq. (1) can be viewed as a rate equation for q where q˙ depends linearly on q itself, a source field r and the second-grade gradients ∇∇q. Owing to the derivation within the kinetic theory and the associated approximations, it is natural to inquire about the thermodynamic consistency within continuum physics. Further, we may look for generalizations suggested by the continuum context. For instance, we may view λ, ν, ζ as constants but even more generally as temperature dependent parameters. Thermodynamically the analysis of (1) is of interest within the so called rational thermodynamics [9] also because so far investigations have been mainly performed through other approaches (see, e.g., [10]). Further, we observe that, in general, the thermodynamic restrictions involve inner products and leave the transverse (orthogonal) parts of vectors or tensors fully undetermined. The application of an appropriate representation formula allows us to look for the general structure of thermodynamically-consistent constitutive equations.This paper has a twofold purpose. First, to examine the validity of the thermodynamic consistency of rate equations like (1) with temperature dependent coefficients. Secondly, to apply the representation formula for the rate q˙ so that a generalization is given of eq.(1) and higher-grade terms, compatible with thermodynamics, are determined.

Representation Formula

The body under consideration occupies the region Ω  in the three- dimensional space. Given an origin O, with any point of the body is associated a vector position x. We denote by ∇ = ∂x  the gradient operator. For any vector, say f , we define the norm |f | by |f | = (f · f )1/2. The symbol Skw denotes the set of skew-symmetric tensors.

Let w, f be two vectors. Letting 2 abve  we have

2 above

If w is subject to

w · f = g                                                   (2)

then

then kinda

If the transverse part w is undetermined then we can represent it in the form

thenkinda

where u is an arbitrary vector. Hence, in view of (2) we can represent w in the form

3

A number of applications of this representation formula, and of the analogous one for tensors, are developed in refs [11,12].

Thermodynamic Consistency of the Rate Equation

Let ε be the internal energy density,  per unit mass, and ρ the mass density. The assumption that the body is rigid makes ρa constant. The balance of energy can be written in the form

4

where q is the heat flux, r is the energy supply, and the superposed dot denotes the time derivative.

Let θ be the absolute temperature and η the entropy density. The balance of entropy is expressed by

4 kinda

where k is the extra-entropy flux and is the entropy production. Substitution of ρr – ∇.q from the balance of energy (4) and using the free energy

5

be the set of variables. We then assume   η , k, ϒ , q˙ are continuous functions of r and    continuously differentiable. Indeed we first let  q˙ be given by (1) and allow λ, ν,  ζ   depend on the temperature θ. Compute ψ and substitute in (5) to obtain

6

To avoid lengthy calculations we observe that replacing q˙ through (1) leads to

6 kinda

as far as the dependence on ∇∇θ and ∇∇∇θ is concerned. The arbitrariness  and symmetry of ∇∇θ and ∇∇∇θ imply before inthat , in that

123

and the like for before thought . Though not necessary we put

weput after

Thus it follows follows after . Moreover the arbitrariness of of after and and after implies

implies after

Hence eq. (6) simplifies to

which pina

which is a restriction on the functions and before and λ, ν, ζ For definiteness we let

789

and 9 after is  constant.  Hence hence after which is consistent with the condition condition after Incidentally, in stationary and uniform conditions conditions after, eq. (1) reduces to the Fourier form

form after

In light of the results (9) we infer

infer after

thus showing that the heat conductivity conductvity after is required to be positive. In addition, the entropy production is

and then

Since since after is the specific heat, we guarantee the condition by before by letting letting after

In summary, we have considered the rate equation for q, as given from the outset in the form (1), and have determined conditions for the thermodynamic admissibility. Instead, we now start with the Clausius-Duhem inequality (5) and look for possibly more general thermodynamically-consistent rate equations for q.

Generalized Rate Equations

Rate equations are now derived by appealing to the Clausius-Duhem inequality (5) and the representation formula (3). We continue to let let after be the set of variables and assume assume after Hence eq. (6) reads

F 1

Since  ψ, k, and ϒ are independent of and after  then the arbitrariness of implies again the classical relation

f 2

For definiteness we keep assuming

F 3

Hence it follows that

10

We then apply the representation formula (3) with the identifications

10 down

Hence the general representation of q˙ is

11

where u is an arbitrary vector-valued function of let after

Models with k = 0

If k = 0 then (11) simplifies to

12

If also u = 0 then we can write

12 (1)

In one-dimensional settings (x-direction) we have

12 (2)

More interestingly, let 12 let after Equation (12) becomes

12 (3)

The particular case 3p 1 results in

3p 2

that is the Maxwell-Cattaneo equation [13,14] with relaxation time 3p 3 and heat conductivity 3p 4

Models with K ≠ O

First we let u = 0 and observe that, by (11), 3p 5 in a non-linear form.

By analogy with eq. (1) we assume

3p 6

where 3p 7 is the second-order tensor with components 3p 8. Hence eq. (11) can be written in the form

3p 9

Notice that

AFTER notice 1

where the prime 0 means differentiation with respect to temperature.

Hence we obtain

after notice 2

If, rather, we let if 1 be constants then then after results in the addition of a term proportional to to after but also a term term after in the expression of q˙ . This shows the qualitative role of u in the formulation of constitutive equations. As an aside, observe that the flux flux after is given in [15]; here the whole value of k is established by (9) subject to the constancy of sigma

Conclusions

Models of nanosystems within continuum physics are often established by using highergrade spatial derivatives so as to account for the mean free path of particles comparable with the geometric dimensions. This paper addresses attention to the Guyer-Krumhansl equation (1) as a prototype of equations with higher-grade terms. Owing to the kinetic derivation of (1) it is natural to contrast the equation with the basic requirements of continuum physics. Here this is performed in relation to the thermodynamic consistency namely the compatibility with the second law via the Clausius-Duhem inequality. Definite conclusions are shown to follow if attention is confined to appropriate coefficients last constant along with the requirements (9)).

Next a rather new approach is developed in that evolution equations are determined by applying a representation formula that makes the consequences of the second law directly operative. In this approach we consider the free energy, the entropy flux, and the entropy production as constitutive functions that eventually generate the desired evolution equation. Some equations derived in this way prove to be highly non-linear.

It seems then that this way is profitable in establishing involved higher-grade equations within continuum physics. The approach though leads also to simple models such as the one expressed by the well-known Maxwell-Cattaneo equation.

Acknowledgments

The research leading to this work has been developed under the auspices of INDAM-GNFM.

References

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Collecting Evidence and Testimonies of Severe Human Rights Violations – The Importance of the Mind

DOI: 10.31038/AWHC.2023621

Abstract

Especially since the recent atrocities in Ukraine and Iran, but also in Syria and China, the close interaction between psychological recovery of survivors, and efforts to investigate and prosecute severe human rights violations has become an issue of concern. Investigations and the collection of evidence, especially witness statements, are conducted by national and international authorities, including international courts, but also by NGOs and journalists. While preservation of evidence, that should be guided by the relevant UN/WMA standard, the “Istanbul Protocol” and witness statements, are an important and necessary part of such investigations, the protection of already psychologically distressed or even traumatized victims against suffering and traumatizing interviews or re-traumatization has become a concern in international, such as EU, standards, and is also mentioned in the Istanbul Protocol as reference standard, but without giving sufficient concrete guidance. Mental health is an important part in this process, as outlined in this article. An interdisciplinary working group of the World Psychiatric Association Scientific Section on Psychological Consequences of Persecution and Torture has developed and tested a new standard protocol that is recommended to be used when interviewing survivors of extreme human rights violations to address this concerns, especially in the context of the important global efforts to involve direct and indirect victims such as family members in collecting evidence as important first step in identifying, documenting, investigating and prosecuting such crimes.

Keywords

Human rights, Torture, Genocide, War, Therapeutic justice, Psychology, Victims

 

Human rights violations, and especially those usual described as “extreme violations” such as torture, war crimes, or genocidal actions, are not only destructive to societies, but also have been demonstrated to have severe, often lifelong impact on the mental health of individuals and communities, including transgenerational trauma transmission [1] and epigenetic sequels [2-4]. They must be seen as the probably at present most severe challenges to public mental health [5,6]. New and usually interdisciplinary strategies and interventions targeting not only individuals but communities and societies at large, might have to be developed and implemented, usually in the context of the general mental health and psychosocial services (MHPSS) approach [7,8] recommended by the UN and WHO. In spite of the development of a number of international legal and humanitarian treaty systems and instruments in humanitarian and human rights law, and of monitoring institutions such as the office of the UN High Commissioner for Human Rights, of International Criminal courts, and of offices of the UN special rapporteurs on subjects like torture, on the rights of women and children, and on genocide, the impunity of perpetrators is still a major challenge so far not sufficiently addressed in an effective way in national or international courts, except in a few exceptional cases. This means not only that the risk of future violations by the same or other perpetrators or countries must be expected to increase, but also that the suffering of victims will continue or even increase [9,10]. New strategies like the application of the legal principle of Universal Jurisdiction [11], that permits countries to prosecute, arrest and put on trial perpetrators of such extreme violations like torture or other crimes under international law, have been implemented in countries such as Germany, Austria, and France, yielding first results and conviction of some perpetrators. This must be seen as an important tool in the unfortunately common situation, that an efficient investigation and fair legal process is not possible in the country of origin of the victims who are escaping to safer third countries such as EU countries or the United States. Evidence is a strong element necessary in this process [12].

One of the key areas identified in this context, is that of an interdisciplinary approach in the collection of evidence and in the psychological support off survivors and witnesses, who must be expected to suffer by re confrontation with highly traumatic memories during witness statements, medical examination [13], and during the court hearings.

Medical evidence, including especially also psychological evidence, can play an important role in this context, and international standards such as the Minnesota protocol [14] and the recently updated Istanbul protocol (Manual on Effective Investigation and Documentation of Torture and Other Cruel, Inhuman or Degrading Treatment or Punishment) [15,16] have been developed and are supported by the United Nations and other international bodies and organisations to ensure proper procedures in examining victims and survivors. The Istanbul protocol also underlines the importance of protecting survivors during examination and during and after the witnessing and investigation process against undue distress and secondary victimisation or re-traumatization by the necessary legal interventions. In a similar way, standards by the European Union (mostly framework directives influencing the legal process in all EU countries), such as the reception guidelines for refugees or the “minimum standards on the rights, support and protection of victims of crime”, have initiated a paradigm shift to underline the importance of such psychological support and protection against secondary trauma in the necessary legal procedures besides legal recommendations.

The EU … states in article 9 of the “crime victims” directive that:

“victims of crime should be protected from secondary and repeat victimisation, from intimidation and from retaliation, should receive appropriate support to facilitate their recovery and should be provided with sufficient access to justice”.

In this context, a number of projects have demonstrated, that giving testimony about human rights violations in an adequate setting can be as or even more important than established medical treatment models or that giving testimony can improve their impact. A probably first example was the “testimony therapy” approach developed in Latin America [17,18] when a legal fight against impunity was impossible during total social control by local dictatorships. Creating a testimony or witness statement against perpetrators of torture by survivors became a key element of this special form of psychotherapy and has inspired also other new treatment approaches [19]. This is an insight that is also used on the level of communities and societies as part of a transitional justice process, for example in so-called truth and reconciliation commissions in South Africa or Rwanda [20-23], though results appear to be not always satisfactory. The discussion compares here the concepts of “restorative” vs. “punitive” justice, but in any case, impunity of perpetrators must be seen as a major challenge to survivors’ psychological health and wellbeing in whatever setting [9]. The EU Network for investigation and prosecution of genocide, crimes against humanity and war crimes (The Genocide Network), Eurojust and the Office of the Prosecutor of the International Criminal Court published on 21 September 2023 guidelines for civil society organisations, which seek to collect and preserve information to contribute to investigations and prosecutions at national level or before the ICC on “Documenting international crimes and human rights violations for accountability purposes”.

A necessary conclusion in this context is, that giving witness statements and evidence for example in proper medical examination and court testimony can be an important part of recovery and healing for survivors and witnesses [21], in addition to supporting the legal process.

Unfortunately, neither the before mentioned standard examination protocols, nor the support of survivors of extreme violence are sufficiently covered by most medical curricula.

The interdisciplinary team of the World Psychiatric Association Scientific Section on Psychological Consequences of Persecution and Torture have therefore developed a training programme and protocol to improve the psychological aspects of evidence collection and to protect witnesses and survivors during the legal process or investigation.

The protocol was applied, tested, and modified as part of a project supported by the UN Voluntary Fund for the Victims of Torture, with survivors of human rights violations from Syria and to Ukraine, in collaboration with legal NGOs active in this process and with the WPA section since 2018.

We developed a protocol focusing on the specific steps of the medical accompaniment and required psycho-social support in the context of collecting evidence and testimonies of international crimes and severe human rights violations based on our work experiences and research. In the following part of this article, we want to present this protocol for discussion and dissemination in the international medical and legal communities, considering especially the possible use in the recently started process of universal jurisdiction, International Criminal courts and the collection of evidence for example in Syria and the Ukraine. The protocol also underlines and is referring to the afore- mentioned Istanbul protocol of the United Nations and the World Medical Association, [15,16,24] and is to be seen as supporting, and not replacing this important standard, focusing on the psychological and mental health aspects of examination, witnessing and witness support.

This last aspect is important, but often neglected in forensic settings in the interaction with survivors and witnesses, who can be seen also as indirect victims, probably due to the historical focus of the forensic sciences either on the bodies, or in forensic mental health on evaluation of perpetrators, or on the evaluation of competence.

We see a psychological and/or psychiatric examination as an integral and important part of the above legal process, keeping in mind that this has to consider the stigma against mental health and the possible distress by survivors during re confrontation with traumatic memories, as also culture specific issues such as cultural idioms of distress, that can be part of the evidence [25-27]. We have summarized the key points on the importance of mental health assessment in Table 1.

Table 1: Summary: Relevance of mental health in the examination of witnesses of crimes

tab 1

Guideline and Protocol

The WPA section therefore recommends the following steps:

(Note: For the following process, we recommend an interdisciplinary approach, and installation of a well experienced and trained team)

  1. Preparation of the case. All evidence available should be collected, and translated by lawyers, and for medical findings by the medical team (Medteam). The Medteam will analyse medical data to identify issues as mentioned in attachment I (note: here: Table 1) and familiarize team members with history and experience of the survivor/witness, in order to better prepare for testimony and examination and avoid repetition of details in the examination, to consult with experts knowledgeable of the situation and of transcultural issues, to identify experts or translators to be added to the process. The team leaders will offer legal and psychological training of the legal and medical team, including in the Istanbul Protocol.
  2. Preparatory contact with witness, to present the team, build trust and confidence and the approach in the protocol, identify further issues as in table/attachment, agree on procedures with client, reduce stigma anxiety, provide support to locate and bring medical and other documentation, answer questions in regard to treatment and legal framework
  3. Conduct “Welcome” meeting with support team on arrival for court hearing, psychological preparation and further rapport and trust building, if necessary or adequate in the process, medical or diagnostic interventions.
  4. Offer support during hearings by legal, medical and psychological team members, and if necessary, organize immediate crisis intervention and medical treatment, including interventions to reduce distress. If required they will also provide advice or specific expertise to the court.
  5. Debriefing and measures for stress reduction and relieve immediately after testimony will be offered
  6. Follow up support including psychosocial support (following the Interagency Standing Committee (IASC) mental health and psychosocial services (MHPSS) model [28,29], provision or organization of medical support, and of further expertise as required by court, team or survivor/witness, including contact with local specialized service institutions.

Summary

Providing for mental health aspects in interacting with witnesses of human rights violations is important not only for supporting evidence collection and aiding investigation and prosecution by lawyers, but also addresses the necessary protection of often psychologically severely traumatized, vulnerable and suffering survivors and witnesses. The guideline/protocol offers concrete advice in protecting witnesses during necessary interviews and examinations, as outlined by the UN Istanbul Protocol. This approach has become even more important in the context of present wide spread violations of international humanitarian and human rights laws in Ukraine, Syria and other countries.

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Developer Goals for e-Commerce Startups: Applying AI-enhanced Mind Genomics to Thinking about Everyday Issues

DOI: 10.31038/PSYJ.2023553

Abstract

Mind Genomics explored responses for an e-commerce website, focusing on a website with ‘deep knowledge’ of the user’s preferences. To understand the application of Mind Genomics in a real-world setting, the timing of the setup and the fielding were limited to a total of 120 minutes. The data were collected in Spring, 2019. Four years later, newly developed AI analysis further interpreted the results. The initial analysis in 2019 deconstructed the ratings assigned by the respondents to vignettes, combinations of messages, describing the website. The respondents used an anchored 5-point scale, with the anchors ‘buy’ and ‘not buy’, respectively. The deconstruction by OLS regression revealed the contribution of each element to the ‘buy’ rating. Clustering the 46 respondents using the 16 coefficients uncovered three Mind-Sets: MS1-Help the client grow, MS2-Client Consulting, and MS3-Generate Leads. Four years later AI was applied to each group in the population, using six standard AI queries applied to all positive elements which were deemed to be strong drivers of ‘buy.’ This paper shows the possibility of rapid and insightful learning on new topics. Learning is promoted through experimental design coupled with human validation, and AI interpretation.

Introduction

The computer, the Internet, the Internet of Things, and the focus on real-time optimization continue to empower our modern age. You can’t go a single day without encountering a constant stream of ads and requests to buy. These advertisements often feature items that have already been purchased or viewed, as well as items left in a shopping cart. They are based on microsecond analyses of the shopping behavior of consumers. The analytic abilities are now so powerful that big data looks antiquated when compared to the small data generated constantly.

This paper explores what could be considered an important issue, the need to improve the flow of information between the customer and the online retailer. Online retailers function best with a large amount of data about their customers.

For roughly a decade, brands and retailers have been promoting their strategies for being “consumer centric” This means that they want to put the customer at the heart of all the work they do. In effect, this puts the consumer into the driver’s seat, with consumers ‘telling the brands’ what brand experience to create for them. When it comes to analyzing consumer behavior and preferences, retail analysts are tasked with interpreting data from consumers – such as sales figures, consumer trends and satisfaction ratings to develop insights for managing the retail enterprise profitably.

Retailers, the brands they carry, and internet service providers are increasingly criticized by privacy advocates and regulators for using data collected from consumers to develop detailed profiles on each one to tailor the commercial experience and to precisely target their messages. In response, most data collectors now offer opt-out methods to limit the data collection, its uses, and sharing with third parties, but doing so is not obvious. There is a widespread growing belief or, at the very least, a loudly expressed recognition, that data created by an individual belongs to them and should be controlled by them, similar to the requirements set forth in the EU’s 2018 General Data Protection Regulation [1].

Our world is inundated with data. As the speed and volume of data increase, our ability to form scientific questions, track trends, or subject the rapid pace of life to scientific inquiry is lost. Amidst massive amounts of data and massive optimization opportunities, it becomes increasingly hard to ‘think slow’.

We are accustomed to the slow, majestic, ingrained, now entrenched system of hypothetico-deductive reasoning [2]. It is a basic concept that scientists, or even individuals, can ‘advance,’ when they form a hypothesis and test it rigorously, trying to falsify the hypothesis. As technology speeds up the production of data and its acquisition, it is also necessary to accelerate knowledge and thought. In the harder sciences like biology and chemistry it may take exceptional creativity to produce knowledge, but in the human-centered sciences this may not be a major problem. With the advancements in computer technology, some paradigm shifts may already be possible [3].

Recurring Issues in the World of More Knowledgeable Websites

With the increasing excitement and, occasionally, almost manic positive responses about websites ‘knowing people’ comes the issue of privacy at the most obvious, but more deeply the morality of machines which have been programmed to learn about people The topic of this paper is the desire of respondents for websites (viz., provider technology) to ‘know them’, or perhaps the opposite, the fear that the machine may know too much, and the consequent loss of privacy. Some of this issue is one’s own desire for privacy, but some of it is the ‘morality’ of machine knowledge about facts relevant to individuals, and the implications of the wide availability of such knowledge. The issue is not ‘all or not’ either, for with knowledge by websites of people comes the smoother operation of interactions, the reduction of annoying, and occasionally harmful friction.

Mind Genomics: The Promise and Vision for the Future

Mind Genomics is a new, emerging science which traces back to three disciplines [4-8]. These are:

  1. Experimental psychology which searches for the causes of human behavior. The specific area of experimental psychology giving rise to Mind Genomics is psychophysics, the discipline which searches for lawful patterns in between what is presented and what we perceive For Mind Genomics that relation is between the words describing a situation and the judgment we say we would make.
  2. Statistics, The respondent reads combinations of elements, messages, describing this ordinary situation, and rates the feeling on a scale provided by the researcher.
  3. Consumer research, which examines how consumers make decisions in everyday life, in which we live, work, succeed or fail. The goal is not to develop a new theory or to disprove an existing one, though these noble endeavors are possible. The only goal is to make sense of these patterns.

It is important now to keep in mind that the effort is more in the world of ‘hypothesis-generating’ than in the world of ‘hypothesis-testing.’ Quite often researchers really have no hypotheses to test but are constrained to do the study as if it were guided by a hypothesis. Mind Genomics does not care about that. It is simply a tool to discover patterns that may be interesting regarding how people think.

The process of Mind Genomics is a simple one, beginning with the question of what do people do about the information they receive as they are instructed to make a decision? Typically, the respondent is presented with the situation, using a simple story, even a single sentence. It is the goal to find regularities and relations within nature. Such discoveries generate the raw material for understanding how people think. When these discoveries are amalgamated from well-done experiments and when they reach critical mass, they form a coherent database, and in turn these coherent databases become the foundation of technology and science.

This study forms part of a new initiative in Mind Genomics which aims to massively accelerate the acquisition of information and insights for everyday life, including topics such as subjective feelings toward e-retailing, including ‘smart websites.’Another motivation is to show, through a research program integrating artificial intelligence and systematized human testing, if the two can be used to reveal aspects of everyday life or even weak signals about changing attitudes.

This study was done in 2019 before the massive expansion of AI into the world of everyday consumer research analytics. The original study was done without any focus on what AI could add to the research effort, but rather focused on what people would want for a system in which they would give up their privacy. The actual data analysis reflects what people were thinking in 2019. The subsequent AI analysis, in turn, was done in the third week, of May 2024, with a view to what the data might mean for a business issue.

The project itself in each phase ran on an accelerated schedule. For the first part of the project, the actual research, the total time involved was less than three hours from start of the project (create the experiment) to the acquisition of analyzed data. For the second part of the project, the AI analysis of the results obtain four years before, the analysis took 30 minutes, consisting of an automated AI-driven reanalysis of the data tables The actual study itself with people came shortly after the first experience integrating AI and Mind Genomic by hand, with AI providing the raw information first, that information transformed into the test stimuli [9]. The effort presented here moves the process in the opposite direction, with AI providing a second, deep analysis of results already obtained.

The First Part of the Project – The Creation and Execution of the Survey with the Respondents

Mind Genomics is now scripted. It follows a templated process which reduces the “angst” of doing experiments as well as the time and effort required to collect data. Experience over a half century has shown that individuals are anxious when asked to “do science.

Mind Genomics scripts are designed to make sure that researchers can present the information in the correct format. In the actual experiment, relevant messages about a subject (called “elements”) are combined into short, easily readable vignettes. A vignette consists of 2-4 messages. People then rate the combinations using a scale. Each respondent ends up rating 24 different vignettes. The vignettes are different for each respondent, but all the elements remain the same [10].

Mind Genomics’ studies have been scripted to allow them to be run on a computer, smartphone, or tablet, with results available in a very short time. The information in Table comes from the study, text taken from the actual input by the researcher, and put together in the report to document the study. The information in Table 1 is available within five minutes after the end of the study, as is the basic analysis. The AI summarization requires an extra 20-30 minutes after the end of the field work. (Table 1)

Table 1: Key information about the study provided by the Excel report.

TAB 1

The setup begins with naming the study and the instructions to provide four questions relevant to the topic of study. Researchers are asked to structure four questions in a way that they “tell a story,” and then provide four answers to each question. Figure 1 shows the template. In 2019, it took several hours to create the four questions for each question and four answers.

FIG 1

Figure 1: The templated request of four questions (left panel) and four answers as used by respondent to manually provide questions and answers.

Since Mind Genomics became available to the public more than 10 years ago as a DIY (do it yourself) technology, there have been many instances where researchers felt overwhelmed with the task of creating the elements.

It is now possible to use artificial intelligence to generate questions. The researcher only needs to write a paragraph into the Idea Coach box in the Mind Genomics template and the AI will return 30 different questions. The Idea Coach technology, which was launched in 2022, was three years after this study was conducted.

Figure 2 shows three additional set up screen shots from BimiLeap. These include the orientation page (left panel), the rating scale (middle panel), and the researcher’s file information about the rationale for the experiment as well as key words for a later search (right panel).

FIG 2

Figure 2: Three setup screen shots for BimiLeap. These are the orientation page (left panel), the rating scale (middle panel) and the file information (right panel).

The researcher can select the respondents’ source using the screen in Figure 3 following the study’s launch. This is done quickly within the BimiLeap software. Respondents are ‘sourced from’ a panel provider that specializes in online surveys. There are a number of panel providers around the world. These panel providers maintain lists of respondents with their qualifications. They are individuals who have agreed, in exchange for a reward from the supplier, to take part in similar studies. The researcher does not need to know about the agreement. The panel provider only needs to find the right respondent.

FIG 3

Figure 3: Sources of respondents selected by the researcher at the end of the project.

Mind Genomics research can include elements (questions, answers, etc.) in many different languages and alphabets. However, the instructions on how to set up the study as it is done by the researchers are only available in a limited number of languages.

The actual experiment with the subject lasted about 3 minutes. The experiment starts with a brief orientation. The respondent then answers a few self-profiling questionnaires (Figure 4, bottom panel). Finally, the BimiLeap program presents 24 different vignettes that have been systematically created. The vignettes contain 2-4 elements, at most one answer to a single question but often no answer to one or two of the questions (see Figure 4, top panel).. It will be this very incompleteness of the combinations which allows the analysis by OLS (ordinary least-squares), and the estimate of absolute values for the coefficients.

FIG 4

Figure 4: Sample four-element vignette (top), and self-profiling classification (bottom).

The experimental design allows for the analysis of each individual’s ratings, respondent by respondent, as well as analysis of groups comprised of any set of 46 respondents who participate in this study. The vignettes have been set up in a way that each person evaluates 24 unique vignettes. This design structure allows the researcher to explore different aspects of a problem without having to select which combination of elements gives the best chance for discovery.

Database Structure, Analysis, and Reports – Total Panel

It is easy to analyze the data because the experiment design has been preselected in a way that all the 24 combinations of different sets are isomorphs. The vignettes are different, but the mathematical structure is identical. The researcher will have a powerful analytical tool that allows them to explore a large part of the “design space” (the combinations). More respondents, and therefore more people, means that more design space will be covered.

A simple database makes it possible to perform the analysis. The database is divided into 24 rows, each of which corresponds with one of the vignettes that a respondent has tested. The database for the study contains 1104 rows, or 46×24, of data. Each respondent contributes 24 rows to the database, one row for each of the 24 vignettes evaluated by that respondent. The Columns are allocated for bookkeeping (row number, how the respondent profiles herself or himself), a column for the order of rating of the 24 vignettes (1-24), then 16 columns to show absence or presence (value 0 or 1) of an element, and finally the assigned rating and the response time. The response time is the number of seconds between the appearance of a vignette and the answer.

The program then creates two binary variables: TOP (ratings 5, 4 transformed into 100) and BOT (ratings 1, 2 and 4 transformed into 100). BimiLeap adds a vanishingly small number of random numbers for each BOT or TOP value to create needed This prophylactic measure ensures the required variability, even if the respondent rates all the vignettes as either 5 or 4 (all transformed TOP become 100) or 1 or 2 (all transformed BOT become 100).

Table 2 shows the parameters of the equation, expressed as: TOP = k0 + k1A1 + k2A2 .. k16D4 . This equation can be estimated accurately because the OLS regression does not have any correlation issues between variables. The coefficients emerging from the OLS are absolute values, so a 5 has half of the value as a 10 It is crucial to understand this necessary property, which allows Mind Genomics to create a science. The researcher can quickly grasp the dynamics in the data revealed by the experiment when the coefficients show the real magnitude of the effects.

Table 2: Elements for the Total Panel which drive TOP (Sounds interesting). Only elements with coefficients > 1 are shown.

TAB 2

As a side note, this vision of absolute coefficients is often counter-intuitive to ‘experts’ who believe that the respondent needs all the information from the different questions to make a decision. Admirable as that point of view is, which ends up presenting complete vignettes to each respondent, the results data is almost impossible to understand, because the absolute coefficients have no meaning. It is only differences which have meaning. There is no possibility of databasing the results unless the entire study is replicated. Only then do the coefficients have meaning.

Table 2 shows the results from the Total Panel, of 46 respondents, each rating a unique set of 24 vignettes. The Table shows us places for the 16 coefficients, along with the additive constant.

This constant indicates the likelihood of respondents saying ‘buy’ in the absence of any element in the vignette. The vignettes are all designed with a minimum of two and maximum four elements. The additive constant can be thought of as a statistical correction factor. On the other hand, we can use this as a base, or a tendency for respondents to respond “buy”. This will help us gain this insight. Table 2 indicates that 45% of the responses will be 5 or 5, when they know what the system is, even when there are no specific elements to qualify the product. We could have measured this change over the years if we had done the same type of experiment.

In the interests of revealing patterns, the convention in this paper and others is to show only positive coefficients of value 2 or higher. Coefficients of 1, 0 and negative are of no interest. The low coefficients indicate that an element’s presence in a vignette “doesn’t add”. This does not necessarily mean the element detracts or is insignificant.

Eight out of 16 elements have coefficients greater than 1. All the rest generate coefficients that are 0 or negative. . However, only one element is really successful, “create amazing ads” with a coefficient of 6. Subgroups are likely to be hiding strong performers, as we shall soon see.

We now move to the AI interpretation of these results from the total panel. AI analysis should only be viewed as a set of tentative observations by a heuristic. AI can provide a quick answer before taking the time to analyze the entire dataset. The BimiLeap report has been upgraded to provide AI responses to the following six queries, using the coefficients for the key subgroup being summarized.

The following are the six queries.

Interested in

Create a label for this segment:

Describe this segment:

Describe the attractiveness of this segment as a target audience:

Explain why this segment might not be attractive as a target audience

Which messages will interest this segment

These queries primarily consider moderate or high performing elements with coefficients greater than +5. The elements with coefficients below 4 are considered, but not relied upon.

The AI summarization of the data, based on the six queries appears in Table 3.

Table 3: AI first scan and interpretation of the strong performing elements for the Total Panel.

TAB 3

Results from Self-profiling Questionnaire

The BimiLeap program instructed respondents to put themselves into one of four groups, based upon how they feel about an outside website having deep knowledge of oneself. Table 4 shows the pattern of coefficients generated by the two polar opposite groups, the first very excited and positive about the situation, the second bothered. As one might expect, the additive constants are higher for the positive group, and much lower for the negative group. Furthermore, there are more strong-performing elements in the positive group. Table 4 shows the coefficients of the elements. Table 5 shows the AI analysis of the patterns.

Table 4: Elements which drive TOP (Buy) for the two key segments emerging from the self-profiling question: How important is it that the website know my mind to give me offers?

TAB 4(1)

TAB 4(2)

TAB 4(3)

Table 5: Elements which drive TOP (Buy) for the three Mind-Sets, emerging from k-means clustering of all the element coefficients from the 46 respondents.

TAB 5

Dividing Respondents According to Mind-Sets Using the Coefficients

The final analysis of the data will be focused on creating Mind-Sets. These are groups of respondents that have been created by using the K-means Clustering Program based upon the similarity of the patterns made by their coefficients. We use the 16 coefficients whether they are positive or negative for clustering. The additive constant is not used in clustering [11].

BimiLeap. It generates two Mind-Sets at first, then three Mind-Sets. The Mind-Sets encompass all respondents. A person belongs to only one mind-set for the two mind-set solution, and again to only one mind-set for the three mind-set solution. The clustering results in meaningful groups that can be interpreted, despite the fact that the process is mechanical and mathematical.

Table 6 lists the elements that make up the successful performance of the Three-Mind-Solution. In order to save space, the two-mind solution is not included. The AI results are shown in Table 7, emerging after applying the six AI queries to the Mind-Sets.

Table 6: AI interpretation of the strong performing elements) by AI for the three-Mind-Set solution.

TAB 6(1)

TAB 6(2)

TAB 6(3)

Table 7: The IDT, Index of Diverged Thought, showing the performance of the elements, and thus the strength of the thinking behind the specific Mind Genomics study.

TAB 7

Understanding Performance Using an Index Number (IDT, Index of Divergent Thought)

Researchers in many fields ask the same question: “How did we perform?” With Mind Genomics and AI still at an early stage, but available worldwide at the touch of a button, it becomes a matter of whether the research produced anything valuable. It is important to note that the notion of “value” does not refer to personal worth of data for the researcher or to reproducibility of science. Instead, for Mind Genomics we ask whether or not the study produced any high-performing elements. When we find strong elements, there’s a link between the element and rating questions. In these studies, the researchers are looking for this link. In those elements, the issue at hand can be better understood.

We present IDT Index of Divergent Thought as part of our effort to “systematize” the use of Mind Genomics, in an era of simple-to-use AI-powered techniques. IDT’s objective is to determine the effect of elements. IDT produces a simple, indexed result. This is shown in Table 8. When we divide the study into six groups, each sum of positive coefficients for that group is weighted by the relative number of respondents for that group. The six groups are Total, Mind-Sets 1 & 2 for the 2-Mind-Set solution, and Mind Sets 1, 2, & 3 for the 3-Mind-Set solution. The IDT is the weighted sum of positive coefficients. The weight is the ratio between the respondents per group and the total of 138.

The IDT by itself is simply an index number about how well the elements performed. With continuing use of the IDT as a metric, it may become possible to measure the degree to which a person grows in the ability to think creatively. One could imagine charting the IDT value for a person or group of people as they are challenged to think through various problems. The IDT gives us a way of measuring the ‘strength’ of alternative efforts to deal with the same issue, with different issues, after teaching interventions, and so forth. The alternatives may be the same researcher over time, the performance of studies done by individuals vs. those done by collaborating groups, and so forth. The IDT is objective, a simple index quickly calculated as part of the report to the researcher.

Discussion and Conclusions

The Mind Genomics method has been used to investigate the decision-making process for the world of the ‘everyday.’ Rather than focusing on topics of deep significance and with a long history of investigation, the researcher using Mind Genomics investigates simpler problems, such as what does a person want from a website which ‘knows’ the user. It is within that world view that the current study was done.

What emerges from Mind Genomics is far more than a simple snapshot of human decision making at the level of the concrete issue. One can sense from the use of commonplace features as elements that behind these everyday statements lay an entire universe of motivations, a universe that might totally disappear or at least lose its vitality if the statement were couched in the general, rather than in the specific. It is the richness in the meaning of everyday experience which provides deep learning. In other words, Mind Genomics provides emotion-rich, philosophically rich metaphors that ordinary, academic language cannot.

Armed with that point of view the paper no longer talks only about websites which know the person. Rather, the paper talks to the issue of emotional responses to different ways of weighting information to decide. different ways of responding to recommendations from a ‘machine’ and the concern with the nature and trustworthiness of machines which know the person. The issues lose a bit in the translation when they are stated in the form of generalities, but create immediate, palpable internal sensations when they are described by daily, identifiable events, viz., by realistic metaphors.

Beyond the actual data from the Mind Genomics exercise, however, lies the second layer of AI analysis. The AI process was told to look at the elements in general, especially those with coefficients of +6 or higher, along with the additive constant, and summarize the results through six queries. The objective of the exercise was to publicly present the data, and then the AI interpretation of the data, untouched by human hands. No attempt was made to structure the output of the AI, this effort being among the first to attempt a machine-level summarization. It is likely that we will see significant advances in ‘insights and languages, as the ever-evolving AI amplifies the structured outputs of Mind Genomics experiments.

References

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Russia’s Domestic and International Politics: No Explanation Possible without the Cognitive- Developmental Approach

DOI: 10.31038/PSYJ.2023552

Abstract

Russia’s war on Ukraine is not a failure by accident but reflects mentality and stance of the Kremlin and greater parts of the Russian people. Russia’s domestic policy is characterized by autocracy and his international politics follows imperial dreams, prosecuted by most brutal methods. Obviously, the political consciousness of the Russians has not progressed to the rates and standards that shape mind and behavior both of politicians and electorate in the most advanced nations of our time. It is argued that political sciences must consider research conducted by the cognitive-developmental approach to understand divergent political cultures more thoroughly. Contemporary nations operate on differently developed stages of mind and cognition with far-reaching effects on moral reasoning, social understanding, and humanitarian standards. There is evidence that a weaker development of the fourth stage of human cognition, the stage of formal operations, accounts to backwardness concerning the process of civilization. This seems to be the main cause to the existence of the chasm between the “Russian World” and the “Free World”.

Keywords

Developmental stages, Civilization process, Political consciousness, International politics, Democracy, Autocracy, Moral values, Humanism

Introduction

Since February 2022, social scientists, politicians, journalists, and the public have been more and more realizing that the differences between Russia on the one side and Western nations on the other side concerning culture, politics, and mentality are much greater than previously assumed. Even a few weeks before the war, only a small number of the 2.000 experts visiting the Munich Security Conference expected Russia was to attack Ukraine, while the majority assumed Russia would only try to blackmail the West and Ukraine for receiving some guarantees and concessions. Many Western observers previously believed that the Russian Federation would share common norms and standards concerning international treaties, territorial integrity, warfare, and humanism at least to that rate to be hindered from starting a brutal war against a nation to whom it had maintained a lot of connections in terms of language, culture, and family ties. Though many experts and observers still continued in preserving their naïve illusions even during the whole year 2022, some others recognized that the war might evidence the huge cultural gulf between Russia and the West, a cultural chasm which has existed for generations and centuries but was overlooked for long. The war threw a new light on how to understand Russia, its society, culture, politics, and people, both the past and the contemporary Russia.

In fact, the tremendous differences are manifest concerning domestic and international politics, economy and judiciary, culture and mass media, family life and morals. They seem to touch every aspect of life, refuting the assumption that the use of modern media, rise of higher education, international contacts, and participation in globalization might prompt and unify the standards of politics and morals on a worldwide scale, at least with reference to the comparison between Russia and the West. It is obvious now that Russia has not shared the advancements in political culture, morals, and humanism to that rate the Western nations, including for example Japan and South Korea, have accomplished over the past generations. Russia has not successfully progressed to heights which are identifiable in the most advanced nations of our time.

Many experts may agree on the existence of this cultural chasm as outlined in the previous sentences [1,2]. However, the cultural gap may be much deeper than most critics of contemporary Russia even believe. I am going to maintain that the cultural gap is describable in terms of developmental stages as they are known and worked out by professional developmental psychology. This kind of research and theory is almost unknown among most political scientists, historians, sociologists, journalists, and politicians. Even the harshest critics of Russia, seeing it as backbencher concerning modernization and progress, understanding it as Stalinist or partially even as medieval, usually have no idea of possibility and necessity to apply developmental psychology to scrutinize Russia specifically and cultural differences between nations generally.

In several essays, E. Fein and A. Wagner have described Russian politics in terms of psychological stage theory, using theories of adult development [3,4]. Adult development describes stage developments unfolding and discernible among adults within a given society or between adults of different societies. This approach illuminates the backwardness of contemporary Russia in a fresh and astonishing way, dwarfing the common political science studies related to Russia by showing their limited precision and their insufficient or almost missing explanatory power.

This article goes beyond that as it erases the boundaries between developmental psychology and adult development theories. Theories of adult development actually do not bridge the gap to child development; it remains unclear how adult development follows those stages children go through. More precisely, theories of adult development sometimes describe about ten stages, maintaining there are some adults in modern societies operating on stages two or three of ten possible ones [5,6]. Then they have the problem to connect these assumptions with the fact that there are prior stages to consider, those provided for children and teenagers. When modern adults might stay on stage three of ten possible ones, where did they stay when they were six or 14 years of age?

Therefore, my own approach solely bases on the most common stage theory known in developmental psychology, on the theory of stage development according to Jean Piaget. It describes four main stages, covering the development from neonate over child and adolescent to adult phases [7]. My approach, called structural-genetic theory programme, is developed as a general theory of history, and expounds the history of human development from archaic to modern societies, including the history of culture, politics, law, religion, sciences, philosophy, arts, and morals (XXX).

Archaic or ancient humans share with modern children stage two and sometimes stage three but do not develop stage four, which is a stage that only adolescents and adults of modern societies are able to develop. The evolution of stage four – the stage of formal operations – originated late in history, usually in Europe during the 17th and 18th centuries, and did not reach the average people before the 20th century. Stage four has evolved stepwise from generation to generation over the past centuries. Stage four has continually grown within the most advanced nations of today, while developing and threshold countries are somewhat behind concerning that development. While the most advanced nations of today stay comparably highest on formal operations, people of threshold countries are more or less somewhat behind, while people living in traditional regions within the developing nations often do not attain the fourth stage at all. These uneven stage developments across world society account for uneven developments of politics, morals, and humanism (XXX).

The structural-genetic theory programme refers for example autocracy, missing human rights, corruption and criminality, maltreatment of women and children, brutal punishment laws, and superstition to lack or weak development of the fourth stage, while a strong development of that stage reversely accounts for democracy, protection of civil rights, humanism, rationality and enlightenment (XXX). Therefore, it is claimed that the comparably cultural backwardness of current Russia must be explained in terms of developmental psychology, that is, it is rooted in comparably weaker developments of the fourth stage in the minds of people.

On the whole, Piagetian stage theory delivers a sharper and deeper foundation to the phenomena mentioned than adult development theories, with foundations that are much more precisely and more consistently based. There is no gap between child and adult development, but adult development is continuously connected to child development. Sciences need only one stage theory, not two of them.

Civilization Theory and Piagetian Psychology

There has been a forerunner of the structural-genetic theory programme. The civilization theory of Norbert Elias [8] shares many assumptions, including the description according to that humankind went through psychogenetic stages from childhood to adulthood. Elias compares ancient or medieval adults to children, seeing adults of modern societies as the only ones to have surmounted children’s stages. He describes medieval humans as people characterized by narrowness of mind, inability to overlook complex relations, cognitive egocentrism, low thresholds of shame and embarrassment, low forms of conscience, strong and wild passions especially concerning sexuality and aggression. According to Elias they have a strong Id and a weak Super-Ego, allowing the I to follow his drives and passions. Modern adults have overcome the child’s psyche and are therefore more civilized. The history of civilization, the transition from medieval to modern times, roots in this psychogenetic development of humankind. Elias recognized that non-European nations have been following this path during the 20th century. According to that theory, Russians can be categorized as backbenchers concerning the civilization process.

Piagetian theory and Piagetian Cross-Cultural Psychology can evidence that what Elias had already described, thereby using better data and theoretical models than Elias had had available. All humans all over the world develop the sensorimotor and the preoperational stages likewise, but then divergences between ethnicities appear. The preoperational stage is the modal stage of archaic or premodern adults, the stage that explains archaic mind, behavior, and culture mainly. Some of them develop also the concrete operational stage, mainly partially and mostly bound to certain issues and tasks. They never develop the formal operational stage, the fourth and final stage [9-14].

The preoperational stage matches to children between their second and their tenth year roughly, and the concrete operational stage covers developments between the sixth and the 12th year of age. The formal operational stage stepwise unfolds between the 12th and the 25th year of age. That implies that archaic or premodern humans usually stay on stages of children between their third and their tenth year, most often between their fourth and their seventh year. Archaic humans may differ in life experience and knowledge from preschool children, but not regarding their psychological stage structures. More, every single phenomenon developmental psychology found to describe children, empirical research also discovered as main feature of archaic adults. The commonalities regarding stage structures are encompassing and complete, leaving no room for any differences whichever. Modern adults, however, distribute on developmental ages between 10 and 25. While some modern adults stay on substage A of formal operations (10-15 years of age), others exhibit substage B (from 15 years onwards) (XXX).

Children and archaic adults share the same patterns concerning numbers, logic, physics, social affairs, political understanding, morals, religious phenomena, and worldview, right across the whole range of mind, consciousness, and world understanding. Both groups likewise believe in ghosts and sorcerers, magic and oracles, and share animistic understandings of nature and movements. Both groups hold on a law-and-order justice and discern laws as holy and unchangeable things. Both groups have religious feelings towards natural phenomena and view the cosmos as some kind of God by itself. Both groups have the same attitudes towards myths and fairy tales and apply the same categories of causality, chance, and probability. Both groups support autocracy and deny democracy. The commonalities include even small details such as the understanding of shadows or the ignorance of syllogisms.

Against this background is it possible to reconstruct the history of culture, sciences, philosophy, religion, politics, law, morals, and arts in terms of developmental stages [15-18]. The preoperational stage carries and defines the historically early stages of these branches of culture, no matter where and when in world history, and the higher stages carry their trajectories through later times. The modern structures of these branches mentioned are mainly nothing else than manifestations of the formal operational stage. On the whole, modern, industrial society simply is a manifestation of the fourth stage. As stage theory is the deepest description of the psychogenesis of humankind, as the structural-genetic theory programme delivers the most fundamental description of the history of the branches because it directly refers this description to the core structures of the four stages respectively (XXX).

Developmental Psychology and Political Studies

Stage Theory and Political Behavior in World Politics

Psychological stages have widely shaped the evolution of political institutions and political thought [19,20]. They do not only account for the existence of autocracy or democracy but also for the rate of brutality and criminality concerning political behavior, or for the values and moral standards shaping political conduct. Politicians governing developing nations have been tending more to brutal and criminal behavior than politicians ruling the most advanced nations of our time. Not political institutions and legal frameworks account for that difference, as most political studies suggest or imply. Psychological stages cause these differences as they cause both institutions and mentality of people. Nations operating on lower stages have no problems in accepting violent rulers, they are loyal to dictators and tolerate their insane methods. Only nations on higher stages rebuke both autocracy and violent and absurd methods of politicians. Political sciences, however, don’t know about the necessity to apply developmental psychology to the study of political phenomena. I have yet published some book chapters and some articles to outline the link between political sciences and stage theory.

For example, the former president of the Philippines, Rodrigo Duterte, won elections for presidency due to his official statements he, as mayor of Davao, had killed drug-users and dealers by his own gun on regular controls he had done through his city with his motorbike. He won the election campaign because the nation wanted to have a strong man capable to solve problems by most brutal methods. Then staying in power, hundreds of private persons and police officers alike received 300 USD for every assassination of both addicts and dealers. More than 10.000 persons were killed anywhere in the streets or in their homes, without any supervision or judicial procedures. More, the Philippines had no special drug problem though, at least less than many other nations (XXX). It is apparent that such phenomena could never happen in the most advanced nations of today, and even not in advanced developing nations such as Brazil or Argentina.

Prince Johnson murdered Liberia’s president Samuel Doe in September 1990 and made a detailed two-hours-film of the slow and brutal torture and killing of Doe. The video became the biggest attraction in Liberia and was widely cast in West Africa over years. It did not endanger Johnson’s presidency but ran in bars and shops from morning to night, entertaining the appetite and appealing the taste of some nations at best (XXX). Again, such things could never happen in Brazil or Argentina. It is impossible to imagine Angela Merkel sitting on a motorbike hunting addicts with her own gun or even Donald Trump casting videos showing a torture of “sleepy Joe”.

Even people with most limited knowledge of developmental psychology should immediately grasp that only stage theory can explain these great differences in political behavior. There are huge differences with this regard between contemporary nations whether political sciences and journalism can address or envisage this or not. These pieces of information are the best precondition to understand the necessity to apply stage theory to political studies, to the ignorance of our intellectual and political elite, and – to Russia.

Stage Theory as Explanatory Model to the Evolution of Democracy

Developmental psychology does not only explain daily political behavior and political mentality. It explains also whether a nation prefers autocracy or democracy. The structural-genetic theory programme has outlined that not social structures or power constellations account for autocracy/democracy but stage developments concerning a nation’s political consciousness (XXX). Jean Piaget delivered the decisive data to develop this new theory of political systems. He evidenced that children by their tenth year roughly see rules and laws as unchangeable and holy, made by God or the elderly. They think people are not allowed to make rules and to govern society on their own, by applying democratic customs and procedures. Teenagers, however, surmount this idea of divine and autocratic government, and establish ideas and customs of democratic leadership. Accordingly, stage theory accounts for the existence both of autocracy and democracy [21]. Subsequent research has repeatedly confirmed Piaget’s early study. Teenagers have a better understanding of liberty rights, tolerance of dissident opinions, and democratic procedures, while children focus on the privileges of rulers and hold on strict principles of obedience [22-30].

Not before 2013 did an encompassing study with about 100 pages exist to evidence that humankind went through exactly the same stages of political systems and ideas as those outlined by developmental psychology, as those found among children. It is now sufficiently and coherently worked out that stage theory is able explaining the rise of democracy (XXX). The gradual rise of formal operations during the time 1750 to 1950 is the main cause to the continuous rise of liberty rights, rule of law, and democracy, first in the West, later on in other regions of the world. The era of Enlightenment worked out the ideas of liberalism, while the era of revolution at the end of the 18th century and the era of modernization during the following centuries put the liberal ideas into praxis and created the institutions of democracy. The emergence of the stage of formal operations has carried the whole process of civilization manifest in political systems, political consciousness, moral standards in political behavior, and political values. The decline of violence, corruption, mafia connections, and warfare mentality is consequence of psychogenetic advancements. This late description or discovery is insofar astonishing as Piaget himself in his early study launched a lot of remarks that there are parallels to history, while for example decades later Radding also made some formulations related, being by no means the only author with this regard. However, it was the structural-genetic theory programme to develop the new theory consistently and fundamentally (XXX).

The Political System in Russia

Russia transformed from monarchy to communist dictatorship in 1917. Democracy existed in Russia only during the last decade of the last century, while since 1999 with Putin in power Russia slowly turned into autocracy again, holding democratic institutions only as a mere façade. Already in the year 2000, the new government overtook greater parts of mass media in order to control public opinion in favor of the Kremlin. By 2008, the Kremlin is said to control 90% of mass media. The new government put former KGB agents into central positions of state and administration with clear intention that the secret service should dominate the whole state and society. In fact, with Putin the former KGB overtook the power in Russia and removed both the new democratic elites and the Jelzin “family” from influential positions. By 2006, 78% of the Russian state elite had a background with the “services”. From the scratch on these people aimed at abolishment of liberalism, democracy, and rule of law. Liberty rights were contained and there was nobody anymore to enjoy legal protection against prosecution or attacks by agents or officials. The division of jurisprudence, legislation, and government slowly dissolved [31].

The new power elite overtook the economic empires made by the Oligarchs of the 1990s and thousands of enterprises, thus dominating whole branches, media, energy, building, finances, etc. They forced former entrepreneurs to resign and to hand over their property, or just killed them, when they refused to give in. It was just brutal force that made the grand robbery feasible. Or, they used justice and police to accuse any businessmen to get their property into their hands. Especially the accusation of not having paid taxes offered a good pretext for expropriation.

It was common that true Mafia organizations killed entrepreneurs, overtook their property, and shared their conquest with either local state officials or even with the Kremlin. Or, that state officials overtook enterprises, thereby using the help of Mafiosi. Coalitions with Kremlin, administration, police, and Mafia became widespread. Robbery, basing on such coalitions, did not only concern enterprises but entailed also private houses or appartements. Violence decided over business success and ownerships referring to enterprises and houses.

The Kremlin dominates at the top of the corrupt system. When gangsters or service agents want see their robbery secured or even guaranteed, then they must share with the Kremlin. The Kremlin receives this way its shares from all parts of economy throughout the country. Secret services or the Kremlin now control 70% of Russia’s Gross Domestic Product. Russia is practically a feudal state where the Kremlin approves ownerships in exchange of shares or contributions. Thereby it is possible that in case of missing loyalty or missing shares, the Kremlin expropriates owners to overtake the property by its own, or by consigning it to other persons or groups. The Kremlin allows or withdraws ownerships from any conglomerates, enterprises, or businessmen for whichever reasons. It is maintained that there does not take place any transfer of capital over 50 Mio. USD in Russia without the personal permission of Putin himself. Therefore, he could accumulate more than 200 Billon USD for his own fortune and build his own “Versailles” close to Sochi.

The slow transformation from democracy to autocracy accelerated since the invasion of February the 24th. Since that time every trace of opposition has vanished, and strict loyalty and obedience is requested from any citizen in the state. The question arises why did the Russian people accepted that transformation? Why did they allow gangsters to overtake office and economy? Why did they endure their slavery and loss of rights? According to the new theory of political systems presented above the ultimate cause to the existence of autocracy is the weak development of the adolescent stage of formal operations. Dictators can only rule when greater parts of a nation support them, accept them and are loyal to them. Without support and wish of the people dictators cannot keep their power and rulership. The existence of autocracies depends on the political consciousness of greater parts of the nation. In fact, psychological stages account for dictatorship.

Without knowledge of the structural-genetic theory programme, authors studying Russia have recognized that the majority of Russians already in the beginning of Putin’s rulership were in favor of autocracy and saw it as the best method to rule the country, to recover both economy and Russia’s greatness in world politics. Russians disrespected democracy and liberty rights as Western propaganda and as accountable to the chaos of the 1990s. The Russian people have elected Putin and his party time and again during the past two decades, especially people living in the countryside and in the provinces. State propaganda has its share but educated people fully staying on the fourth stage would neither swallow this propaganda nor back the whole system generally. “A majority of people deliberately accepted the new system that cemented the way of government prevailing in Russia since the time of the czars.” The deep connection between political consciousness of people on the one hand and the actual political system on the other hand completely matches to expectations of the psychological stage theory mentioned above. The structural-genetic theory programme claims to be able to explain the primitive and uncivilized political system of Russia.

Theories of Adult Development and the Political System of Russia

Elke Fein and Anastasija Wagner belong to those having applied theories of psychological development to the study of Russian society. They use, as mentioned above, theories of adult development to understanding contemporary Russia. They apply among others the stage theory of social forms and political behavior outlined and devised by Stephen Chilton [32]. The lowest stage 1 (“punishment and obedience”), expressed by physical compulsion, threats, seizure by force, and extortion, is manifest in pecking orders, slavery, and prisons. The second stage (“individual instrumental purpose and exchange”), expressed by barter, trading, bribery, deterrence by revenge, prebend, curses, exhibits in feudal systems, patronage systems, and hostages. The third stage (“mutual interpersonal expectations, relationships and conformity”), expressed by friendship and romantic love, is to find in client systems, social patronage, and corporatism. The stage four (“social system and conscience maintenance”), basing on mutual support of moral system, manifests in modern army, bureaucracy, tyranny of majority rule, and absolutism. Stage five (“prior rights and social contract or utility”) includes mutual respect, rational debate, fair competition, and scientific testing, and materializes in democracies and preservation of civil rights and liberties. Finally, stage 6 (“universal ethical principles”) bases on mutual care and undistorted communicative action and is still Utopia.

According to Fein, the Russian society after 1990 by today displays a mixture of stage 2 and stage 3, basing on patron-client-relations, clientelism, barter, or “blat”. Therefore, democracy and rule of law, tolerance and civil rights could not function in Russia because the political consciousness of people has been too weakly developed. Institutions can function only on that level of developmental complexity people have attained in their mind. “Unless the institution’s structure is preserved by people at the appropriate stage, the institution will regress to less developed forms.” The Russian political elite and electorate could not adopt the democratic institutions and practices introduced by B. Jelzin and thus the new formal institutions came to be devaluated in favor of clientelism, patronage, and brutal violence.

Thus, there is no great gulf between the political system of the USSR and that of contemporary Russia, at least measured by some criteria. The Soviet regime was ruled by “truth” and “dogma”. It was an ideological dictatorship, basing on clientelism and patronage, thus exhibiting the levels 2 and 3 according to Chilton. Stalinism was created by the Georgian clan culture.

The political consciousness of the Russians did not advance and remained blockaded on earlier stages, those stages that already prevailed in the USSR, and could not compete with the advancements taking place in the West especially between 1970 and today. “Modern and postmodern values and logics have neither become the dominant structures of public reasoning nor of political action on a larger scale. Sustainable post-conventional action logics, for example, would also include post-materialist and other post-conventional values, such as critical self-reflection, putting higher weight on good relationships and inner growth as compared to material goods, increasing feelings of empathy, tolerance, and respect for other cultures, social and political minorities and even the rights and dignity of political opponents.”

Fein also resorts to the stage theory of Susanne Cook-Greuter. Stage 0 (pro-social) is followed by stage 1 (symbiotic) and stage 2 (impulsive). Stage 2/3 (self-protective) bases on minimal self-description and characterizes many Russians including Putin. Stage 3 (conformist/rule-oriented) is followed by stage 3/4 (self-conscious) and stage 4 (conscientious), then by stage 5 (autonomous) and stage 6 (unitary). I do not comment Cook-Greuter’s stage theory here. Fein earmarks an early stage such as 2/3 as modal stage of many Russians, and this shows at least that Fein sees the Russians as tremendously backward in terms of personality development and political consciousness. Self-protective persons (stage 2/3) “see the world only from the perspective of their own needs and wants. They are as yet incapable of insight into themselves or others in a psychological sense. This is why they are generally wary of others’ intentions and assume the worst. Everything to them is a war of wills, and life a zero-sum game. Their ‘I win, you lose’ mentality inevitably causes friction and hurt feelings wherever they go, especially with others at more conventional stages. In turn, others experience self-protective people often as manipulative and exploitative, because in their perspective, the only way one can get what one wants is by controlling others and protecting oneself.” According to that research, self-protective individuals do not feel responsible for failure they cause, because they do not understand the connection between action and consequences. “Others are to blame, never oneself.”

Wagner and Fein researched the behavior of Putin by using several data bases, especially by analyzing his speeches, articles written about him, and other sources. The data were coded and interpreted by the stage theory of Cook-Greuter. They found Putin’s mind and behavior matching to stage 2 with 24% of his actions and statements, to stage 2/3 with 46%, to stage 3 with 25%, and to stage 3/4 with 5% of them. Thus Putin’s personality is dominated by the self-protective stage. “This structure does not show empathy with others, and often does not view them as equal others with legitimate, potentially differing perspectives on things. Instead, it perceives all outside actors and events through an egocentric, somewhat narcissist lens, primarily asking: ‘how does it affect me?’ and ‘what’s in it for me?’… And due to a lack of more differentiated coping strategies, they consequently try to control, hunt or eliminate them by all means. If there are no enemies, they invent or create them.” Fein shows that this attitude characterizes both the treatment of other nations and the own past. Russian foreign politics sees the ambitions and problems of other nations in an astonishing way only through own lenses. For example, Russia cannot recognize that the Eastern European nations’ hurry for membership to NATO or other alliances originated in its own conduct against these nations. Russia caused the problems but is incapable to connect its own mistakes with the unpleasant results and therefore always blames others.

The same attitude is identifiable concerning the interpretation of the own past. Russia addressed his own past seriously only during the Jelzin era, with “Memorial” that researched the crimes of the Stalin era, and with historians to scrutinize Stalin’s responsibility for the outburst of war [33]. Afterwards, with the beginning of the Putin era, the open and critical confrontation with the own past radically declined and was finally abolished. Stalin, the USSR, Russia’s role in the war, and the whole past was glorified and whitewashed, any form of criticism of the own past was prosecuted and criminalized. “I claim that self-protective logics of reasoning and action have come to function as a strategy to avoid a more differentiated confrontation with the after-effects of these dislocations and with the Soviet past in general, at least during the past ten years.” Higher psychological stages, being able to self-reflexive operations, do not whitewash own mistakes and ignore them but would accept them as facts. “Even psychological lay people would probably agree that self-reflexive efforts to confront past crimes and traumas constitute a more complex, more differentiated and thus more developed way of dealing with a criminal and traumatizing past than trying to whitewash, repress, or relativize it, for example by setting it off against the ‘positive sides of history’ or by denying or avoiding questions of responsibility.”

Since Putin took office as president, Russia’s rating on Transparency International’s Corruption Scale has dropped from rank 82 in 2000 to rank 136 in 2014 (www.transparency.org). While in Western societies, during the past centuries, models of cognition and social conduct have developed from concrete, interpersonal logics to more abstract and formal logics, Russian society preserved the concrete-personal relations as dominant form of society, thus continuing traditional relations such as patronage, clientelism, and corruption. Corruption belongs to everyday practices in traditional society and is seen as problem only when society attains the mode of preserving abstract rules and impersonal functionalities.

Premodern peoples usually stay on moral stages 1 or 2, only small percentages of a premodern population reach stage 3 [34]. These three stages manifest moral reasoning bound to concrete personal relationships only. They ignore any moral considerations referring to society, abstract rules, or general principles. Only stage 4 refers to abstract bodies such as state and society, that is, principles and institutions outside the range of personal interrelationships. Therefore, the problem of corruption can only be recognized on stage 4. This stage 4 was nonexistent in imperial Russia and seems to be missing or only very weakly developed in contemporary Russia. Corruption can only be defeated when people attain the stage 4 at modal stage, otherwise persons see no problem in preferring those who pay most or to whom they are personally connected. Corruption is visible as problem only when rule-oriented cultures of reasoning (at least stage 4) and their respective action logics emerge.

“Historians have described society in late tsarist Russia as a society of physical presence or as a gift giving society, in which the efficiency of power depended on the quality and stability of personal networks. The latter, in turn, were built and stabilized through practices of exchanging material and immaterial goods against loyalty, personal service, or obedience. Patron-client relationships were universal, unquestioned phenomena structuring the whole society, including its social, economic, and political institutions. At the same time, typical elements of modern statehood, such as impersonal institutions, the rule of law, and professional work ethics based on personal skills, formal qualifications, and specialized knowledge were nonexistent.”

Clerks were not appointed due to their qualifications but due to their personal relationships to patrons. Offices were distributed as reward for loyal behavior to the aristocrat, ultimately to the Czar. There was no spirit of lawfulness and strict obedience to rules, as Weber had described as prerequisite of modern bureaucracy. Higher education and professional education were missing in 19th century Russia. While Germany had already a three-stage school system and two state examinations as condition to join state service, Russia introduced compulsory school education not before 1917 and demanded from clerks only the knowledge of reading and writing but not any specific skills. “Most officers served exclusively because of the honor or of earning a certain rang or medal, without really taking an interest in the files or in the essence of the matter. They signaled anything that came to them by the chambers” [35].

Though higher qualifications and abstract rules played a higher role during the Soviet regime, it is quite obvious, that patron-client relations, clan structures, and blat-relations (personal networks to receive goods and to circumvent formal procedures) have dominated the Soviet society throughout the last century. “The Russian mentality is oriented toward personalizing one’s contacts… In Russia, formalities never meant more than personal relations. It is a country which is governed by mores rather than laws” [36].

This stage of consciousness has continued in Russia by today. Concrete personal relations and moral stages below stage 4 still shape contemporary Russian mentality. “Many observers therefore continue to think of corruption and the direct exchange of services based on relations of mutual trust as the true organizational principle of Russian society.” Russia is a patrimonial and neo-feudal state. Most archaic social relations continue, including clan structures, Mafia structures, and secret service networks to undermine market economy, rule of law and democracy. “In this sense, it is not accurate to say that impersonal systems in today’s Russia are ‘defect’. Rather, they have never fully developed in the first place due to a lack of sufficiently complex reasoning structures able to sustain them as a dominant culture… So even though a general developmental progress of cognition and culture can be analyzed here, post-Communist Russia still does not meet the modernity standards set by Weber. This is due to a missing systematic-stage political culture, which neither the Soviet nor the post-Soviet Russian government was interested in fostering. This also explains the difficulty of modern type (systematic-level) democratic institutions to take root in Russia.”

Social Affairs and Morals in Contemporary Russia

When Russians have developed the fourth stage of formal operations in a weaker way than people of the most advanced nations have done, as the previous analysis evidences, then Russian society is expected to manifest lower stages of personality development, social norms, and morals throughout. I want to document this by some short descriptions of the role of violence in society, the role of street fights, the impact of domestic violence, the situation in prisons, alcoholism, and the treatment of handicapped persons. These different phenomena emerge from a lower stage of personality development and moral consciousness than most advanced nations have reached during the past generations. Using the terms of N. Elias, it is quite apparent that Russian society is less civilized than some other nations are nowadays.

The enormous readiness of Russian people to exert cruel violence currently manifests in its war on Ukraine. While some politicians such as Gerhart Baum adamantly deny any difference between Russian aggressiveness and those of other nations in wartimes, not only the American Institute for the Study of War but also other observers maintain the special aggressiveness and cruelty of the Russian army not only today but also in former times [37]. Butscha und Irpin reflect the normal way of Russian warfare. “What happens in Ukraine over the last three months is an orgy of epic, unbounded violence. Mass executions and bestial torture, assassinations of civilians, just so, just for boredom, for fun, with rapes and murders of parents before their children’s eyes and conversely, with violence against women and girls between 8 and 80 years of age.” [38] Jeffrey Hawn maintained that the Russian army, quite different to Western armies, has not developed an institutional culture to minimize losses among civilians; there simply are no protective mechanisms against unjustified violence in place. Main targets of the Russian attacks are apartment blocks where thousands of normal people live. Destruction of whole cities, as already practiced in Syria, to take civilians all means to survive, is the normal Russian way of warfare. Waiting for the winter to destroy power stations and heating facilities to hope for the death of thousands of civilians in their cold homes, this is a normal strategy in the eyes of Russian military. “Russia has presented to the whole world its senseless Russian anger, its sinister barbarism, his criminal mentality, cruelty, violence and its contempt of human dignity and human life, both that of Ukrainians and its own soldiers.”

Deadly and bloody gladiator fights in arenas before thousands of spectators belonged to the most influential entertainment opportunities of ancient times (XXX). This culture of violence has vanished due to risen psychological stages shaping morals and emotions. Residual forms of that may exist in current box fights, while in Russia harder forms of entertainment fighting have survived, combats that would be impossible to stage in Western Europe. The custom is called Strelka championship (mixed-martial-arts combats) conducted right across Russia. Everybody in the streets is allowed to participate at the combats, without any preparation and exercise. The organizer asks bystanders to enter the ring and to join, giving them joke names and money when they win. Those, who fight bravely and in an entertaining way, can become famous across the country. The fighters are simply amateurs that fight each other without any rules [39].

This culture of violence penetrates the personal and family relations likewise. Russian statistics document 50.000 crimes in 2015, where violence in private homes was involved. 36.000 of them refer to violence used against women. According to UN statistics, 14.000 women in Russia are annually killed by their relatives, especially by their husbands. 40% of all crimes, that entailed use of violence, took place in private homes and family. Especially 2/3 of heavy body injuries and premediated assassinations are committed inside the own family. 600.000 women are annually beaten in Russia. Since March 2017, a new law passed the Duma to remove all those attacks, which do not cause remaining body damages, from penalty consequences. Those persons, who cause only moderate injuries, are not prosecuted by law, but must pay for regulatory offences only [40]. Though the US population has more than double the size, only 1.800 women are killed in the USA. The ratio with this regard between the USA and Russia thus amounts almost 1:20, albeit the USA exhibits much more violence than European nations do. For example, 122 women were killed in Germany in 2018.

Domestic violence is frequently accompanied by alcohol. According to Russian police, 80% to 95% of culprits commit domestic violence under alcohol abuse. Every fifth Russian dies from alcohol abuse, according to WHO statistics. Alcohol causes more than 50% of deaths in the age groups between 15 and 54 years of age, with reference to men 59% and to women 33%. Alcohol intoxications, liver cirrhosis, injuries and homicides under alcohol impact belong to the special causes leading to death [41]. Alcohol abuse is typical for many developing nations and was also a great problem in Europe generations ago but has decreased over time in consequence of education and greater consciousness. In Africa, alcohol abuse has played a great part till yesterday or even today, greater parts of whole village populations were drunken on an almost daily basis. It can be maintained that there does exist a link between the civilization process and alcohol consumption.

Russia manifests his brutal behavior against human beings also in his detainment policy. 480.000 people were imprisoned in Russia in March 2021. Only the United States have higher rates of imprisonment than Russia has. The chance to get imprisoned is great as judicial courts convict most of the defendants: If persons are charged, they have still little chance to get rid of accusations and of conviction to go to jail. While European nations at the average pay for every prisoner 68,30 € per day, Russia has the lowest costs with 2,40 € per prisoner per day.

The Russian detainment system does not aim for resocialization of personality but for its breaking. Withdrawal from sleeping, total ban of speaking, torture, beating, raping, and electro shocks belong to common practices. Or some prisoners must stay in frost or in uncomfortable body positions over hours. The cells are overcrowded, and the staff exerts his power without much control [42,43].

Similar tendencies are to find in the treatment of handicapped persons. Nearly 10% of people living in Russia suffer from handicaps, though these 14 million people are hardly seen in public. It is widely avoided to hint at their mere existence, as handicaps are not subject of official discussion. Since Soviet times, most people shares negative attitudes against handicapped persons, they are seen as people with low worth. Parts of people wanted them even to be eliminated. Though Western NGOs did a lot to improve the situation of handicapped persons in Russia, public transportation, offices, and the whole public space do not consider the needs of handicapped persons. Elevators, ramps, sound signals, and braille are widely missing to relieve their mobility [44,45].

Usually, handicapped persons are removed from their families and brought to shelters for disabled. In Soviet times, families were not even allowed to rise their disabled children on their own. However, still nowadays it is usage that they spend their lives in shelters and not in their families. Time and again, they were tied to their beds, beaten, locked in their rooms, and completely socially ignored. Handicapped persons are usually excluded from education and job market. “There aren’t any institutions to employ mentally handicapped persons in a responsible way. When these persons have finished their school, then they have nothing to expect from the employment system.”

War on Ukraine

Some weeks after the occupation of Crimea, I prognosticated Russia’s try of total conquest of Ukraine in future. I wrote that the only possibility to rescue Ukraine from that fate would be the deployment of sufficient Western troops in the country (XXX). Ukraine had no hostile feelings against Russia by 2013. Ukraine’s commitment to democracy and rule of law, and his wish to join European Union, caused Russia’s readiness to undermine Ukraine’s policy by brutal force [46-50]. Instead of continuing friendly relations with Ukraine, Russia decided to subdue Ukraine by war. The result was a unified and patriotic Ukraine that will hate Russia probably for generations. Outcomes of that policy are a hostile Ukraine, decisive resistance of democratic nations around the world, Russia’s decline of power and influence in many parts of the world, decline of its GDP for many years, problems of preserving power in Russia, thousands of casualties in Ukraine and Russia, devastation of Ukraine’s infrastructure, industry, and towns, and uncountable damages and injuries.

Only a tremendous weakness of formal operations, consciousness, rationality, and overview, including a to that matching far-reaching lack of information and knowledge, can cause such failures. Only people staying on lower stages of formal operations are inclined to disrespect the rights of other nations, to believe that they themselves have the right to decide over that what other nations should do and whether they have the right to exist as independent nations or not, to start wars to conquer a foreign nation and to subdue its population, and to sacrifice thousands of people for such criminal targets. Only uncivilized and criminal persons lead wars for imperial dreams, for the enlargement of territory, and for restauration of former influences, causing losses not seen in Europe for many decades. Only persons staying on lower stages of the civilization process disrespect a couple of international treaties, international law, and humanitarian standards. It is incredible that there are persons that are inclined to devastate a so-called brother nation, thereby even maintaining the non-existence of any difference between Russians and Ukrainians.

Observers rightly estimated that the war on Ukraine is not only “Putin’s war”. Greater parts of the Russian people support imperial dreams concerning the restauration of the Russian Empire with Ukraine as an indispensable part. These people accept that Russia has the right to decide over its influence sphere and over Ukraine’s policy. They support wars when they lead to victory and to an increase in power. Even the consideration of state propaganda cannot divert from the fact that only weakness of formal operations – weakness of political consciousness and morals – can explain such uncivilized stance.

Conclusions

It is apparent that the wrong policy of the West, that is, the missing containment of Russia and the lacking prevention of Russia’s invasion, has originated in illusions concerning the civilization level of Russian society. Due to the missing education in Elias’ civilization theory and the structural-genetic theory programme, Western politicians and journalists simply overlooked the backwardness of Russian society generally and Russian policy specifically. They simply assumed that Russians politicians would share the political consciousness, the moral stages, the humanitarian standards, and the values that are deeply rooted in the minds of politicians and people living in the most advanced nations of today. They could not even imagine the abysses that separate the “Russian World” from the “Free World”. The prevalent ideology of Cultural Relativism penetrating the minds of the educated elite in the West has caused these illusions mentioned.

Of course, there are percentages of people in Russia who strictly object to the course of the Kremlin and to the backward stance of Russia. Those Russians, who fight against the Kremlin policy, express the better part of Russia and have deserved greatest respect. Mikhail Kasjanov, Alexei Navalny, Irina Scherbakowa and Marina Owsjannikowa belong to the large group of Russians that represent the best Russia has to offer. They align with those Ukrainians such as Ihor Terechow, Dmytro Kuleba, Wolodimir Selenski and Sergij Osachuk, who define higher standards of European politics.

Declarations

Funding and/or Conflicts of Interests/Competing Interests

The article was written without any funds. There are no conflicts of interest to report. The article aligns with the binding ethical standards.

Compliance with Ethical Standards

Disclosure of potential conflicts of interest: There are no conflicts to report. Research involving human participants and/or animals: The study does not base on experimental procedures conducted with humans or animals. Informed consent: There are no other persons whose interests might be infringed, or no ethical standards to be violated.

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Subjective Responses to Retail Analytics: Applying AI + Mind Genomics to Thinking about Everyday Issues

DOI: 10.31038/PSYJ.2023551

Abstract

Through the use of Mind Genomics coupled with AI (artificial intelligence), the researchers explored responses to an almost totally new topic, retail analytics, specifically what might be the applications in the business environment. AI generated four questions about the use of retail analytics, and subsequently four answers (elements) to each question. These AI-generated answers were combined into unique sets of 24 vignettes, one set for each of 50 respondents. The ratings of the respondents in terms of ‘interests me’ were then deconstructed into the contribution of each element to the rating. The deconstruction by regression analysis was done for total panel, for two viewpoints about what a company would do with the data (better prices; better service), and three mind-sets or ways of thinking about the topic (MS1 – Focus on price/profitability; MS2 – Focus on innovation/operations; MS3 – Focus on outside world behavior, MS 3). The paper concludes with AI analysis and summarization of the strong performing elements for each identified group, using the same six queries for summarization. The paper demonstrates the potential for rapid, insightful learning for new topics, a learning promoted by AI and by human ‘validation’ of the ideas generated.

Introduction

This paper presents an exploration into what might be considered a specialized topic, subjective responses to retail analytics.

“Retail analytics involves using software to collect and analyze data from physical, online, and catalog outlets to provide retailers with insights into customer behavior and shopping trends. It can also be used to inform and improve decisions about pricing, inventory, marketing, merchandising, and store operations by applying predictive algorithms.” [1]

As this definition shows, retail analytics involves extensive data collection, complex analysis and presentation so that executives can make decisions for the benefit of their retail operations. For the analytics, there is the analyzed. Today’s marketing savvy consumers know that data is collected from them, and they expect the data to be used for their benefit, viz. personalized services and an improved shopping experience [2]. It’s an implicit contract.

For years now, retailers and most brands, promote their goal to be “consumer-centric,” i.e., putting the consumer at the center of everything a retailer or brand does, in effect placing the consumer in the driver’s seat, a position allowing them to tell brands how to shape brand experiences for them. Oddly, when it comes to retail analytics, the conversations are about executives interpreting consumer data – sales, trends, satisfaction levels to name three, but we could not find examples where the views of consumers about the use of – and how to use – retail analytics, which is derived from their data, to improve their shopping experiences. This gap provided the novel opportunity to contribute new knowledge by turning the research of subjective responses to retail analytics on its head – to explicate the bottom-up perspectives of consumers to executives, leaders who may then become even more consumer-centric in ways that benefit their operations and improve their customers’ experiences.

Our modern age continues to grow in technological capabilities, empowered as it is by the computer, by the Internet, by the so-called Internet of Things, and by the hyperfocus on optimizing in real time. One can scarcely go through a day without being exposed to ceaseless streams of advertisements and calls to take a buying action. Often, the advertisements are for items already purchased, for items recently viewed or for items abandoned in an e-commerce shopping cart, such advertisements and calls to act emerging from rapid, micro-second analysis of people’s shopping behaviors. Indeed, the analytic capabilities are so strong that the previous fad for gaining substantial insight, big data, looks almost antiquated in terms of the ability to deal with small, immediate, personalized data, generated nonstop.

It is no wonder that the world is awash in data. Our ability to formulate scientific questions, to track trends, to subject this rapid life to the slow majesty of scientific inquiry seems to vanish as the speeds and volumes of data feeds increase to an accelerating beat. It is difficult, indeed, to, ‘think slowly’ while in in the throes of massive data, massive opportunities to optimize.

We are accustomed to the slow, majestic, ingrained, now entrenched system of hypothetico-deductive reasoning [3]. The basic idea is that science, or perhaps even people personally, ‘advance’ by forming a hypothesis about something, and rigorously testing that hypothesis, attempting to falsify Whatever is not falsified begins to have the ring of truth to it. At the same time as technology is speeding up data production and acquisition, there is a need to speed up knowledge acquisition and thinking. It may require exceptional innovation to create knowledge in the hard sciences, such as biology and chemistry, but to create valuable knowledge in the softer human-centered sciences may be less of a problem. Indeed, with the advances already made in computers some of the paradigm changes may be within today’s grasp.

Mind Genomics, the Promise of AI, and a Vision of the Future

The study is part of the new effort in Mind Genomics to accelerate the acquisition of knowledge and insight for the world of the everyday, and for topics involving human feelings about situations and activities that we often overlook because of their sheer invisibility, such as our present topic of subjective feelings towards retail analytics. There is another motivation as well, the desire to demonstrate through an ongoing research program, whether the combination of artificial intelligence with systematized testing among humans can reveal new aspects of daily life, and even point to weak signals of attitudes which are evolving.

The underlying science, Mind Genomics, is an emerging discipline with rooms in a number of areas, including experimental psychology to search for causation of behavior, statistics which allow researchers to work with combinations of independent variables in the way which often occurs in nature, and finally consumer research which looks at how people make decisions about the world of the ‘ordinary’, the quotidian reality in which people actually live, function, thrive or fail.

The history of how Mind Genomics emerged or better ‘evolved’ has been told before, in detail. The story is simple, involving the basic question of how people respond when asked to evaluate a compound stimulus comprising a variety of features. The question is simple, and even the thinking is rudimentary. The sole focus is simply to see ‘what happens.’ The effort is simply to find patterns in nature. There is no effort to create a theory, to prove or disprove a theory, although those noble efforts can certainly occur. The worldview underneath searching for patterns in nature come from psychophysics, the branch of experimental psychology, which searches for regularities in nature, such as the perceived sweetness of different concentration of sucrose in a water solution [4], or perhaps more of interest to industrial concerns, the perceived sweetness of different combinations and concentrations of artificial, high-potency sweeteners, in beverages. The effort is to discover relations in nature, regularities. The mass of such discoveries, especially in a defined and coherent field, becomes technological know-how and even the basis of science.

The project itself was run on an accelerated timetable, the total involvement being less than three hours, although spread over two periods, the first being the set up and empirical experiment, the second being the automated analysis using artificial intelligence. These two together constituted the period of less than three hours. The writing of the paper took considerably longer, but plans are underway to make the writing as quick as the design and the field research. In that way the Mind Genomics approach can be a living instantiation of what studies are, namely decision making in real time in the real world of the everyday. It is worth noting that the first use of AI in Mind Genomics goes back four years, with the process being long because it was a handcrafted combination of AI and Mind Genomics [5].

Part 1 – The Creation of the Study, and the Execution with Respondents

Mind Genomics studies are now scripted, following a templated procedure which reduces both the effort to acquire data as well as the ‘angst’ involved in doing an experiment. A half-century of experience by author Moskowitz in the world of science has continued to reveal that anxiety reported by individuals who are not scientists in their daily lives but are asked to ‘do science’ for a specific objective.

The scripting for Mind Genomics is set up to ensure that the researcher can provide the necessary information, in the proper format. The actual experiment involves combining relevant ‘messages’ about a topic (called ‘elements’) into small, easy to read ‘vignettes’, a vignette comprising 2-4 such messages. The combinations are then evaluated by people, using a rating scale. The respondents each end up evaluating 24 different vignettes, the vignettes for one respondent different from the vignettes for another respondent, but the set of elements being the same. Each respondent rates a unique set of 24 vignettes [6].

Mind Genomics studies are now scripted so that the studies can be set up on either a computer or a smartphone, run, and results downloaded with a short period of time. Table 1 provides key information about the study, information that will be explicated. The text in Table 1 comes directly from the report, contained in an Excel workbook, which can be downloaded either immediately for partial analysis (without the artificial intelligence summarizer), or after 30 minutes for complete analysis (with the artificial intelligence summarizer).

Table 1: Key information about the study provided by the Excel report.

TAB 1

The set-up begins with the naming of the study, and then the instruction to provide four questions germane to the study topic. The researcher is prompted to structure the four questions so that they ‘tell a story.’ During more than a decade, from the time that Mind Genomics was opened to the public as a ‘software as a service,’ there has been increasing number of situations where researchers seemed to have been overwhelmed by the task of creating elements. With the advent of artificial intelligence, such as Chat GPT, it has become easy to use AI to create questions. All the researcher has to do is write down a short paragraph in the Idea Coach ‘box’ in the Mind Genomics template, and the AI returns with 30 different questions.

Figure 1 shows the request for four questions (left panel), and the four questions provided by the researcher (right panel). Table 2 shows one run of the Idea Coach, returning with the 30 questions after the AI has been prompted by a short description of the project. The actual time for this first step with the Idea Coach is approximately one 60-90 seconds after the researcher provides the Idea Coach with the small description. The researcher can select 0-4 questions. The questions selected are automatically put into the template. The researcher can then repeat the action to get other answers. The actions are independent of each other, so that each use of the Idea Coach to provide questions is independent of the previous use. In this way a person new to the topic can learn a great deal about the topic, even without selecting questions. It is the sheer number of different questions presented in a short period of time which constitutes an ‘education’ for the researcher on the very topic being studied. It is for that reason that the approach is considered ‘Socratic.’

FIG 1

Figure 1: The templated request for four questions (left panel), and the four questions provided by the Idea Coach (right panel).

Table 2: The 30 questions returned by Idea Coach after being prompted by a small paragraph about the purpose of the study.

TAB 2

The next step consists of providing four answers to each question. Once again the Idea Coach comes into play. This time the information provided to Idea Coach is in the form of a query, that query created directly from the text of the specific question. When the researcher wants to change the query, it becomes a simple task of editing the question.

Figure 2 shows the formatted screen for Idea Coach, with the left panel showing the request for four answers, and the panel showing the completed set of answers used in the study. Table 3, in turn, shows 15 answers generated from one run of the Idea Coach, with the first question. The time elapsed in about 30 seconds.

FIG 2

Figure 2: The templated request for four answers for question #1 (left panel), and the four questions provided by the Idea Coach (right panel).

Table 3: The 15 answers returned by Idea Coach after being prompted by Question #1.

TAB 3

Once the study has been launched with the appropriate respondents, done easily within the BimiLeap program, the researcher selects the source of respondents, using the screen shown in Figure 3.

FIG 3

Figure 3: Source of respondents, selected by the researcher as the last part of the project set-up.

The respondent is ‘sourced’ from a panel provider specializing in on-line surveys. Across the world there are many such panel providers. These providers have lists of respondents and qualifications, individuals who have agreed to participate in similar studies for a reward provided by the supplier. The researcher need not know the agreement. All that is necessary is for the panel provider to source the correct respondent.

The Mind Genomics study can have elements (questions and answers) from different languages, and different alphabets, although the instructions for the actual set-up as done by the research are currently available in just a few languages (e.g., English, Chinese, Arabic Hebrew.

The actual experiment with the participant lasted approximately 3-5 minutes. The experiment begins with a short orientation provided by the researcher, obtains responses to the self-profiling questions (including age and gender, not shown here), and then presents the respondent with the 24 different, systematically designed vignettes. The vignettes comprise 2-4 answers (elements), at most one answer from a question, but often no answers from a question.

The experimental design ensures that the ratings from each respondent can be analyzed separately, as well as being able to be analyzed as part of the group. The vignettes are set up so that each individual evaluates a unique set of 24 vignettes, a design structure which enables the researcher to explore many different aspects of an issue, without having to choose what combination of elements give the best chance of discovery.

It is important at this juncture to keep in mind that the effort is more in the world of ‘hypothesis-generating’ than in the world of ‘hypothesis-testing.’ Quite often researchers really have no hypotheses to test but are constrained to do the study as if it were guided by a hypothesis. Mind Genomics disposes with that, freely representing that it is a discovery tool, to identify patterns which may be of interest in the way people think about a topic. The respondent sees an introduction to the study, usually presented in shortened form so that the specific information must come from the elements selected by the researcher. Figure 4 (top panel) shows the orientation question. Figure 4 (bottom panel) shows the five-point scale used by the researcher. Some of the text is cut off from the scale description. Figure 5 (top panel) shows the additional self-profiling questions as these appear to the respondent at the start of the evaluation by the respondent. Figure 5 (bottom panel) shows a clear reproduction of a vignette, as prescribed by an underlying experimental design. To the respondent there is no ’underlying pattern’ to be discovered. Rather, the vignette itself looks like it was randomly assembled, in virtually a haphazard manner.

FIG 4

Figure 4: Respondent orientation screen in set-up program (top panel), and rating scale specifics in set up program (bottom panel).

FIG 5

Figure 5: Screen shot for the pull-down menu of self-describing questions (top pane), and example of a four-element vignette plus rating question/scale as the respondent would see it on a full screen (bottom panel).

Database Structure, Analysis, and Reports – Total Panel

Almost fifty years ago, it was possible to accelerate the acquisition of data and even the preliminary analysis of such data. One could gather data quickly, and using mark sense cards and later electronic input one could analyze the data by programs then available, usually programs which specialized in descriptive analysis. The objective for this exercise is to move dramatically beyond that simple original analysis, pushing the limits by making use of smart experimental design, clustering, and applied artificial intelligence using GPT.

The actual data analysis is straightforward, made so by the judicious use of the experimental design, pre-selected so that the different sets of 24 combinations are really isomorphs of each other. Although the actual combinations, the vignettes, all differ from each other, mathematically the structure of each set of 24 vignettes is the same. In this way the researcher is assured of having a powerful analytic tool, which explores a great deal of the ‘design space’ (the possible combinations). Clearly, more individuals, more respondents means more of the design space is covered.

The analysis is made possible by the creation of a simple to use database. Each row of the database corresponds to one of the 24 vignettes tested by a respondent. Thus, for this study, comprising as it does the responses of 50 individuals, the database contains 50×24 or 1200 rows of data. The columns themselves are divided not bookkeeping columns (row number, study name, respondent number, test order number for the respondent, via 1-24), then 16 columns devoted to showing absence of element (value 0) or presence of element (value 1), and finally, the rating assigned, and the response time. Response time is defined as the number of seconds from the appearance of the vignette to the actual response assigned.

After the data are collected, the program creates new variables, specifically a binary variable TOP (ratings 5 and 4 transformed to 100; ratings 3, 2 and 1 transformed to 0), and a second binary variable BOT (ratings 1 and 2 transformed to 100, ratings 3, 4 and 5 transformed to 0). The BimiLeap program adds a vanishingly small random number (<10-4) to each BOT and TOP value, in order to ensure variation in the values of TOP and BOT. This prophylactic action ensures that there will be the necessary variability even when the respondent rated all vignettes either 1 or 2, or 3, 4 or 5,.

The first analysis generates an equation relating the presence/absence of the 16 elements to the newly created dependent variable TOP. Table 4 shows the parameters of the equation, expressed as: TOP = k0 + k1(A1) + k2(A2) … k16(D4). . The use of an experimental design, permuted across the 50 respondents to create 1200 vignettes, ensures that the OLS regression will not encounter any problems in terms of variables correlated with each other. The coefficients have absolute value, viz., a 5 is half the value of a 10. This is important. Often it is only differences in coefficient values which are relevant, e.g., when the experimental design calls for each vignette to have exactly one element from each question. That ‘tempting’ requirement substantially weakens the results.

Table 4: Elements for the Total Panel which drive TOP (Sounds interesting).

TAB 4

With the recognition of these properties of the regression results, the researcher can quickly understand the dynamics revealed in the experiment. The results are immediate and obvious once the meaning of the coefficients is understood. The coefficients tell us the proportion of times a response to the vignette will be 5 or 4 (here … ‘sounds interesting’) when the element is put into the vignette.

Note: Other binary dependent variables can be created

BOT = rating 1,2 transformed to 100. ‘Does not sound interesting’

RATE52 = rating 5,2 transformed to 100. ‘Could deliver’

RATE 41 = rating 4, 1 transformed to 100. ‘Won’t deliver’

Table 4 shows us 17 numbers, the additive constant and 16 coefficients. Mind Genomics studies generate a large number of coefficients. We are not interested in the coefficients which are 0 or lower. These low coefficients say that the presence of the element in the vignette ‘does not add’. It does not mean that the element actually detracts, or perhaps just as likely, the element is irrelevant, leading to a rating of 3.

The additive constant tells us the proclivity of the respondents to say ‘sounds interesting’ in the absence of any elements in the vignette. By underlying design, the vignettes all comprise a minimum of two elements and a maximum of four elements. Therefore, the additive constant is simply a correction factor in statistics. ON the other hand, we can use it as a baseline, a proclivity for the respondent to say, ‘sounds interesting’. We will use it to gain that insight. Table 4 shows the additive constant to be 70, meaning that when it comes to knowing that the topic will be store analytics, 70% of the respondents will be strongly positive. Had we done this type of experiment across years ago we could have measured the change in this additive constant to get a sense of how new ideas are accepted.

Only three of the 16 elements generate coefficients of 1 or above. The remaining generate coefficients of 0 or negative. For the sake of clarity, and for the sake of allowing patterns to come through, we do not show any 0 or negative coefficients. If we discard the element with coefficient 1, quite close to 0, we are left with the finding that of our 16 best guesses using artificial intelligence, edited by a human researcher, we end up with only two strong performing elements, and indeed only modest performers at that.

Shown these results and presented with the Mind Genomics approach for the first time, the critic of artificial intelligence might aver, perhaps even strongly aver, that these results contradict the claims of AI proponents that AI can be as good or better than people. The reality is not as positive, however. When a person selects the elements alone, quite often the person does about as poorly, or perhaps slightly better.

C4: Analytics and modeling can help improve transportation management to reduce shipping costs and lead times.

D3: Data analytics can be used to monitor social media activity, helping retailers identify trending products and capitalize on buzz.

Before moving on to an analysis of subgroups and mind-sets, it is instructive to see what AI can provide in terms of a standardized interpretation of the results. The analysis by AI should be considered simply as tentative observations made by a heuristic. It will still take a person to go through the data, but in the interests of speed, one might employ the AI heuristic to get a sense of the answers before spending time with the results.

Table 5 shows the response of AI to six queries. These queries are listed below.

  1. Interested in
  2. Create a label for this segment
  3. Describe this segment
  4. Describe the attractiveness of this segment as a target audience:
  5. Explain why this segment might not be attractive as a target audience:
  6. Which messages will interest this segment?

Table 5: AI first scan and interpretation of the strong performing elements (6 and higher) for the Total Panel, on six queries.

TAB 5

The queries look only at the moderate and higher elements, viz., those with coefficients of +5 or higher. Elements with coefficients of 4 or lower are ignored. For our data in Table 4 using the Total Panel the AI uses only two of the 16 elements to write its analysis.

Results from Self-profiling Questionnaire – What will the Store Do with the New Analytics

Our second analysis parallels the first, this time focusing on how the respondent feels about what the store will do with the analytic information. The actual question and answers appear below. Out of four possible answers, most of the respondents (43 of 50) chose only two, better price and better service, respectively.

If a store knows a lot about customers, do you think the store will

1=Offer better prices

2=Satisfy the customer more

3=Help make a better world

4=Use the information to its own advantage

Two groups or segments emerge, those who feel that the store will offer better prices using the analytics data (15 of 50), and those who feel that the store with use the information to better satisfy customers (29 of 50). Both have similar additive constants (63 and 69) but respondent in radically different ways to the elements.

The data for this new analysis comparing different points of view on what will the store do with the analytics appear in Table 6 for the coefficients, and Table 7for the AI summarization. Once again all coefficients of 1 or lower are not shown. In the interests of simplicity, all elements without at least one coefficient of ‘2’ Table 6 suggests that the response of those in Segment 1 (believe the store will offer better prices) are strong and focused, whereas there are no strong performing elements for Segment 2 (believe that the operations will be better) (Table 7).

Table 6: Elements which drive TOP (Sounds interesting) for the two segments emerging from the question self-profiling question: If a store knows a lot about customers, do you think the store will…

TAB 6

Table 7: First scan and interpretation of the strong performing elements (6 and higher) by for the two segments, based on the self-profiling question of what the store will do with the results from the data analytic.

TAB 7

Results from Dividing Respondents into Mind-Sets Based Upon the Pattern of Coefficients

Our final data analysis will focus on the creation of mind-sets, groups of respondents who are put together by the k-means clustering program [7], based upon the similarity of the patterns made by their coefficients. For the clustering we use all 16 coefficients, whether positive or negative, although we only show the positive coefficients in the results. Clustering does not use the additive constant.

The clustering program is embedded in the BimiLeap program, generating at first two mind-sets, and then totally once again, three mind-sets. Each respondent is assigned to only one of the two or three mind-sets. Furthermore, the mind-sets encompass all respondents.

The objective of the clustering exercise is to discover hitherto unexpected groups of respondents based upon the patterns of their coefficients from thousands of small studies clustering based on coefficients emerges with meaningful, interpretable groups of respondents, even though the process is purely mechanical and mathematical.

Table 8 shows the positive performing elements for the three-mind-solution. The two-mind-solution is not shown in the interest of space. Table 9 once again shows the AI interpretation of the results, obtained by applying six queries to each of the three mind-sets.

Table 8: Elements which drive TOP (Sounds interesting) for the three mind-sets, emerging from k-means clustering of all the element coefficients from the 50 respondents. Only those elements with at least one coefficient of 2 or higher are shown.

TAB 8

Table 9: AI interpretation of the strong performing elements (6 and higher) by AI for the three-mind-set solution.

TAB 9

In contrast to the data from the Total Panel, and the data from the Self-Defined Segments regarding what the company will do with the segments, the division by the pattern of coefficients shows strong performing coefficients, and meaningful stories which repeat from the two-mind-set solution (data not shown in the interest of space.).

Beyond Interpretation to Understanding Performance at a Glance

A continuing issue emerging from these small-scale studies is ‘How did we do?’ The same question is asked by researchers in most areas, with the underlying issue touching on ‘did the experiment work?’ With Mind Genomics coupled with AI at the very early stages, and available world-wide at the press of a key, the issue becomes the degree to which the study generated anything of value. The notion of ‘value’ is not the personal value of the data to the researcher, nor value in terms of scientific reproducibility and validity, but rather did the effort lead to any strong performing elements. We learn that when we have strong performing elements there is a strong link between an element and the rating question. That linkage is what the researcher seeks in these studies. Knowing that some elements get high scores and other elements get low scores tells the researcher she or he can move in the direction of the high scoring elements. It is in those elements that the relevant issue can be further understood, at least in the minds of the people who are the respondents.

As part of the effort to ‘systematize’ the use of Mind Genomics in this era of easy-to-use techniques empowered by AI, we present the IDT, Index of Divergent Thought.

The objective of IDT is to measure the impact of the elements. The IDT generates a simple index, shown in Table 10. Each positive element is weighted by the relative number of respondents when we consider the entire study as six groups (Total, Mind-Sets 1 and 2 in the 2-Mind-Set solution, and Mind-Sets 1, 2 and 3 in the 3-Mind-Set Solution). Each of the six groups has a specific number of respondents, which add up to 3x the base size, or 3×50, viz. 150. The IDT is simply the weighted sum of the positive coefficients, the weight being the ratio of the number of respondents in a group versus the total number of 150. Note that the two-mind-set solution was developed, but not shown in the interest of space.

Table 10: The IDT, Index of Diverged Thought, showing the performance of the elements, and thus the strength of the thinking behind the specific Mind Genomics study.

TAB 10

The ideal use of the IDT at these early days of implementation is to determine how good was the choice of elements. The IDT for this study is 33.05, on the low side. Keeping in mind that the elements were obtained from AI, and only modestly edited, we have with the IDT a way to quantify the strength of the ideas as they are perceived by people.

Discussion and Conclusions

As emphasized above, this study was undertaken as a study of an experience, the experience being the efforts to learn about a topic new to the senior author, viz., sustainability in the world of retail analytics. The original idea for this study came from a call for papers from the newly founded journal ‘Sustainability.’ The fact that the senior author had little experience with the topic of retail analytics, and indeed scarcely, if ever, thought about the topic, made the study more interesting. As a senior scientist, with 54 years of experience after the PhD., the topic was interesting simply because it asked the question ‘what really could be learned by and contributed by a novice, albeit a novice with professional experience.’

In fact, we learned that our respondents, who are also consumers, can easily grasp the features and uses of retail analytics, and that they reveal three distinct Mind-sets towards retail analytics. Mind-set 1: Focus on price/profitability; Mind-set 2: Focus on innovation/operations; and Mind-set 3: Focus on the outside world behavior. Each of these newly discovered mind-sets educates retail executives with knowledge never known to them before, guidance from consumers about how they might leverage retail analytics for their customers’ benefit and, perhaps, unleashing innovation benefitting both the shopper and the retailer. They can break from past tradition of analyzing from on high what they think is best for their shoppers.

The actual study was easy to implement. The use of the Idea Coach made things easier, although it was not clear to whether these were the ‘right questions’ to ask. The answers were not the issue. Rather, it was the questions, leading to the realization that emphasis is research should be put on asking an appropriate, meaningful question. So many of the AI generated questions seemed real until thought through, with the question of ‘what type of answer would this question engender’

The actual process itself revealed some unexpected benefits. The key benefit might be said to be ‘sharpening’ and improving the question, until one reaches a powerful question. The reality of this single powerful question is important. We are not taught important, seminal questions to ask. And all too often, when these questions are asked, their importance is often unrecognized.

To sum up, this paper demonstrates the increasing ease with which a novice can use computer technology to learn by exploration. The templated version of Mind Genomics makes it possible for the novice to move quickly from issue to empirical results. At the front-end AI provides a Socratic way of creating questions, that create an education on the topic. At the back end, the AI allows the researcher to understand the results from a variety of perspectives, provided by the different queries.

If we were to surmise the potential of the approach, we might find its greatest use in the world of education, to teach [8]. Teaching may not be limited to students, but rather ‘teaching’ here is used in the general sense, to instruct a person about a specific topic [9,10]. The unique combination of AI at the front and back, coupled with real human responses, provides a powerful tool to explore many dimensions of being, from the simplest to the profound, rapidly, iteratively, and with the potential of opening entirely new disciplines as the information from related studies is aggregated into a coherent whole with many different facets.

References

  1. Oracle Corporation (2023) “What Is Retail Analytics? The Ultimate Guide.”
  2. Kinsey MC & Co. (2021) “The value of getting personalization right—or wrong—is multiplying.”
  3. Sprenger J (2011) Hypothetico‐deductive confirmation. Philosophy Compass, 6: 497-508.
  4. Moskowitz HR (1971) The sweetness and pleasantness of sugars. The American Journal of Psychology, 84: 387-405.
  5. Zemel R, Choudhuri SG, Gere A, Upreti H, Deitel Y, et al. (2019) Mind, Consumers, and Dairy: Applying Artificial Intelligence, Mind Genomics, and Predictive Viewpoint Typing. In Current Issues and Challenges in the Dairy Industry. Intech Open.
  6. Gofman A, Moskowitz H (2010) Isomorphic permuted experimental designs and their application in conjoint analysis. Journal of Sensory Studies 25: 127-145.
  7. Likas A, Vlassis N, Verbeek JJ (2003) The global k-means clustering algorithm. Pattern Recognition 36: 451-461.
  8. Clancey WJ, Hoffman RR (2021) Methods and standards for research on explainable artificial intelligence: lessons from intelligent tutoring systems. Applied AI Letters 2:53.
  9. Kim TW, Mejia S (2019) From artificial intelligence to artificial wisdom: what Socrates teaches us. Computer 52: 70-74.
  10. Lara F, Deckers J (2020) Artificial intelligence as a socratic assistant for moral enhancement. Neuroethics 13: 275-287.

Empowering Students in a University through Rapid Design: A Demonstration Involving the Creation of Messaging about Elderberry Wine

DOI: 10.31038/PSYJ.2023544

Abstract

54 respondents from an internet-based panel across the United States each evaluated uniquely different sets of 24 systematically varied ‘vignettes,’ (combinations of messages) about elderberry wine. The messages were created by artificial intelligence (Idea Coach), and afterwards combined into the vignettes according to an underlying experimental design which prescribed the appropriate combinations to use for subsequent regression analysis. Respondents rated each vignette using a two-dimensional rating scale, one dimension representing fit to the respondent (for me vs not for me), the second dimension representing understandability of the message. The data reveal three mind-sets. The study demonstrated the simplicity, speed, and economics of combining artificial intelligence, experimental design, and subsequent human evaluation. The output becomes a scalable bank of subjective information on a topic which is unfamiliar (elderberry wine), with this bank of information combining Socratic learning in a new topic coupled with feedback from real consumers about the information developed through artificial intelligence.

Introduction

The development of new products in the world of commerce is often costly, error-filled, and unduly long. Some of the issues may result from risk-avoidance, a phenomenon rampant in corporations, especially in slow-moving categories such as foods and beverages. When a company in electronics, for example, fails to avail itself of important technology to create new products that company is likely to suffer, often quickly, as its competitors rush to overtake it, doing so at hot speed. Not so in the world of food, even the world-of food start-ups, where the feeling is that there is not really much risk, that the competition moves slowly, and the technology is really not as valuable as the instincts and intuitions of the entrepreneur or the corporate president. The foregoing holds in classic, multi-layer multi-nationals as well as in the starts powered by the ingenue entrepreneur.

At the same time that the world of food development moves cautiously, there is an evolving world of speed, at almost any price. This world has emerged during the past decades due to the confluence of three factors, respectively the computer for processing, the internet for connection, and most recently artificial intelligence (AI) for rapid ‘thinking’ or at least rapid and seeming intelligent processing of text information in a way which seems intelligent. These three factors are making it possible to create ideas, test these ideas, and even expand them in what figuratively be an ‘eyeblink’ in the corporate timeline. What took hours, days, weeks, now can take minutes and seconds.

With the foregoing paragraphs as background, the author has begun a series of studies, small studies to be sure, on topics of daily life. The approach uses experimental design of ideas, mixtures of ideas presented to the respondent, the ratings of these mixtures revealing how each idea or message ‘drives’ the interest of the respondent. Using these tools of computer, internet, and now artificial intelligence, the author has pushed the study of ideas in the food industry down from a pedestal of scientific perfection to an act that even a grade school student can do, and even master after a moderate amount of practice [1-3].

The Mind Genomics Approach – Steps Towards Rapid Ideation

In order to demonstrate the power of new methods for product design, the author conducted a class experiment in April 2023, with students from the University of Florida in Gainesville. The approach was a DIY (do-it-yourself) approach for an advanced version of conjoint measurement, Mind Genomics. The specifics of Mind Genomics have been presented in detail in various papers published since the early days of the 21st century. The reader is encouraged to look at the different topics covered. This paper will once again present the method, and the new development enabled by popular and available methods for artificial intelligence using the popular Chat GPT [4-6].

The ingoing, perhaps heretical and counterintuitive assumption, was that one could do a study within two hours, a study beginning with little or no knowledge about a field and emerge after those two hours with deep information about a topic. The topic chosen during the active initial back and forth was ‘elderberry wine,’ a wine of Asian origin (No et. al., 1980). The students who designed study had heard of elderberry wine, but were not familiar with the wine, making the exercise a challenge and enjoyable learning experience. The choice of elderberry wine emerges after about an unmoderated, 20-second class ‘discussion’ about ‘a topic, any topic having to do with foods.’

There is a modest-sized literature about elderberry wine, but a growing one, because of due to evolving consumer interest. At the same time, elderberry has received attention by horticulturists as well in part because of the increasing recognition of its health properties [7-11].

Table 1 presents the input information about the study. The table comes from a summarized report of the study automatically generated at the completion of the field work. The table provides the study title, date, purpose of the study as the researcher defines it, keywords for later sorting, self-profiling attitude questions, the respondent orientation (kept very simple), and the rating scale. All of this information is automatically incorporated into the Excel report.

The Mind Genomics process is templated, following choreographed sets which set up the experiment, run the actual experiment, and automatically analyze the data.

Table 1: Information about the study provided by the Excel report returned to the researcher at the end of the field work.

TAB 1

Introduce to the Process and Select the Topic (Elderberry Wine)

The exercise was set up so that the students would be introduced to the Mind Genomics process through a two-minute ‘elevator pitch’. The class was told that they would choose a topic, run a study, get results, and discuss the preliminary results. The students we unprepared, but as noted above, the decision was made to study elderberry wine. It is important to note that in no way was the topic to be focused on a so-called ‘burning issue’ or ‘hole in’ literature. The topic was selected almost randomly. It was at this point that the study had been registered as ‘elderberry wine’, the class as researchers filled out some checklists on using English as the language, and agreeing to not obtain information that could identify the respondents, except with the permission of the respondents.

Create Four Questions through Idea Coach

Mind Genomics works by a Socratic method, posing questions to obtain answers, combining the answers, and having respondents evaluate the combinations. Figure 1 shows the screen requesting the four questions (left panel), and the four questions actually selected (right panel).

FIG 1

Figure 1: The request for four questions dealing with elderberry wine (left panel), the Idea Coach for generating questions through AI (middle panel) and the four questions selected from the AI suggestions (right panel).

To generate the four questions in Table 1 is generally a function of one’s familiarity with the topic, and the predilection of the research group to come to an agreement. Often the group is unfamiliar with the topic, necessitating what ends up being interminable discussion and delay as the individuals in the group grapple with the appropriate questions to ask. The issue becomes even more vexing when the parties feel that they only have ‘one chance’ to run the experiment. It is at that point, the feeling of one-chance-only, that the participants in the research program end up ‘freezing’, often with the unhappy consequence that the project falls apart.

During the past several years users have continued to request, and eventually insist that the set-up of a Mind Genomics experiment be more ‘user-friendly.’ Almost all suggestions have included something about making it easier to generate questions, and to a lesser degree, to generate answers to the questions. As an aside, it appears that instead of trusting their own intuition and thinking, many individuals prefer ideas that have somehow been ‘vetted.’ This desire to have assistance in creating questions and answers, that assistance provided by an electronic ‘third party’, led to the creation of the Idea Coach. The Idea Coach is simply a set of AI prompts, based upon the ‘squib’ written about the topic. The squib is submitted to the AI program embedded in the setup, and generates 25-30 questions. Table 2 shows 60 unique questions emerging from four passes though the Idea Coach. With 30 questions there should have been 120 questions, but only 60 were different from each other.

Table 2: 60 unique questions emerging from four runs of the Idea Coach, each run returning a set of 30 questions about elderberry wine.

TAB 2(1)

TAB 2(2)

TAB 2(3)

Create Four Answers to Each Question through Idea Coach

Idea Coach once again uses artificial intelligence to generate sets of 15 answers to each question. The researcher can select the answers of interest and edit them. Table 3 shows the answers for the first question (flavor profile) from three consecutive iterations of answers. In this case the 45 answers differ from each other. Figure 2 shows the screenshots of the final set of answers to the four questions selected.

Table 3: Three sets of answers to the first question (flavor profile)

TAB 3

 

FIG 2

Figure 2: Screen shots of the four answers to each question

The mechanism by which Idea Coach provides the questions and answers remains a trade secret of the company providing the AI system. What is important, however, is the rapid ‘learning’ by the Socratic method, question-and-answer, although here the learning might be in from parallel questions and answers, as the squib generates 25-30 questions, and the question generates 15 answers. One might happily imagine the potential of educating oneself on a topic such as elderberry, simply by two, three, four, or even five iterations of squib → 25-30 candidate questions → 15 candidate answers for each candidate question.

Create an Experimental Design Which Specifies the Combinations of Elements (Answers)

Rather than instructing the respondent to rate each of the 16 elements, one element at a time, the Mind Genomics approach presents combinations of these elements, short descriptions of the wine. Short descriptions are easier to judge because they tell a more complete story than do single elements. The respondent will evaluate a set of 24 vignettes, the aforementioned combinations.

In the experimental design element (viz., answer) appears five times in the 24 vignettes and is absent 19 times. No vignette comprises more than one element from any question. As a consequence, 20 of the 24 vignettes contain one answer from a question, whereas four vignettes of 24 are absent answers. Finally, across all 24 vignettes there are combinations comprising two answers, three answers, and finally four answers, but no vignette with only one answer. This specific design ensures that the researcher can analyze the data using standard statistical tools such as OLS (ordinary least squares) regression [12].

A unique, patented aspect of Mind Genomics is that each respondent evaluates a different set of combinations. The mathematical structure of the combination remains the same, but the specific combinations differ from one respondent to another. This difference is created by a permutation scheme described by [13]. The benefit of the permutation scheme is that the researcher need not know anything about the topic. The experiment allows the researcher to explore a great many combinations, analyze the data at the level of the individual respondent, and as a result uncover patterns that might not even have been imagined at the start of the study.

Create an Orientation and then Create the Rating Question that the Respondent Uses to Evaluate the Vignette. The Orientation is Simple: Read this Description about a New Elderberry Wine. How Do You Feel?

The rating scale actually comprises two dimensions. The first dimension is interest (Not for me vs For me). The second dimension is understandability (don’t get it versus get it). The two dimensions allow the researcher to understand the mind of the respondent more deeply, both in terms of emotion (for me / not for me) and intellect (get it / don’t get it).

Tell us what phrase best fits …after you read this.

1=Not for me … AND just don’t get it

2=Not for me … BUT I do get it

3=Can’t answer

4=For me … BUT just don’t get it

5=For me … AND… I do get it.

Create Self-profiling Questions

The Mind Genomics process enables the respondent to profile herself or himself on attitudes that would not be known from knowing who the response IS. At the start of the study the researcher can create up to eight such self-profiling questions. In addition, the Mind Genomics process automatically asks the respondent’s age and gender. The foregoing information (self-profiling as well as age and gender) are attached to the data provided by the respondent when rating the vignette. The self-profiling information will be used to create subgroups. Figure 3 shows an example of a self-profiling question. The Mind Genomics program allows the researcher to create up to eight such self-profiling questions, each with eight answers.

FIG 3

Figure 3: One of the self-profiling questions

‘Field the Study’ with Respondents

Figure 4 shows the information that the researcher provides to the Mind Genomics program. This information includes the number of respondents, how the respondents will be sourced, and whether or not the researcher wants to ‘privatize’ the respondent data. As of this writing (May 2023), the Mind Genomics platform is very low cost for the artificial intelligence (Idea Coach and summarization in the results). The researcher can either provide her or his own respondents at a low cost ($2/respondent for processing), use a third-party group ($2/respondent for processing), or use a Mind-Genomics approved supplier (Luc.id), with an approximate per respondent fee of $4-$6 for recruiting and processing. The researcher can make the data fully private for an extra $2/respondent. In this way the Mind Genomics fees can be kept very low, a boon to students who can explore a topic in depth, and actually run a small (or large study) on elements of interest, if desired.

Not shown is the set of screens which allow the researcher to specify country, age range, gender, education, income, children, and so forth for the respondent. The typical ‘field time’ to execute the experiment is about 60 minutes for 100-200 easy to find respondents.

FIG 4

Figure 4: The researcher specifies parameters about the field execution

Create the Database

Each record of the database corresponds to a vignette. The record has these columns:

Column 1 – Study name

Column 2 – Respondent identification number

Columns 3,4 – Age, Gender Columns 5-6 – Answers to the two self-profiling questions created by the researcher

Columns 8-23 – One column for each of th 16 elements. When the element is absent from the particular vignette, the cell has the value 0. When the element is present in the particular vignette the cell has the value 1. This is called ‘dummy coding’.

Column 24 – Test order of the vignette. Each respondent rated 24 vignettes, so the test order ranged from the first vignette tested (coded 01) to the last vignette tested (coded 24)

Column 25 – Rating assigned by the respondent to the vignette.

Column 26 – Response time in 100ths of a second, defined as the elapsed time between the presentation of the vignette on the screen and the time that the respondent assigned the rating.

Column 27-30 – Create four new binary variables by a re-code of the rating to a binary valuer 0 or 100 (as well as the addition of a vanishingly small random number to the newly created binary variable)

Column 27 – Create variable ‘For Me.’ Ratings 5, 4 re-coded to 100, rating 3, 2,1 re-coded to 0.

Column 28 – Create variable ‘Not for Me’. Ratings 1, 2 re-coded to 100, 3,4,5 re-coded to 0.

Column 29 – Create variable ‘Get It’. Ratings 5,2 recorded to 100, rating 4, 3, 1 re-coded to 0.

Column 30 – Create variable ‘Don’t Get It’. Ratings 4,1 re-coded to 100. Ratings 5,3,2 re-coded to 0.

The database is set up for dummy variable regression analysis, either at the level of the individual respondent or at the level of the group. The original experimental design specified 24 different combinations, with the combinations being precisely those which ensure that each element appears equally often, and that each of the 16 elements are statistically independent.

The analysis will focus only on the ‘For Me’ ratings.

Create Equations (Models) Relating the Presence/Absence of Elements to Ratings

The equations are estimated using OLS (ordinary least squares) regression. For this analysis we express the equation in the standard way, using an additive constant:

Binary Variable = k0 + k1(A1) + k2(A2) … k16(D4)

The additive constant, k0, shows the expected percent of responses to be assigned if there were no elements in the vignette. Of course, by design, all vignettes comprise a minimum of two and a maximum of four elements so that the additive constant should be considered a baseline.

Search for the Patterns

The patterns should emerge from the coefficients for the dependent variable ‘For Me’ (ratings 5 and 4 converted to 100, ratings 1,2 and 3 converted to 0). Table 4 shows the coefficients for total panel and for binary gender (male vs female). Mind Genomics returns with a great many coefficients. Table 4 and the remaining tables of coefficients (for mind-sets) show only the positive coefficients, viz, those 2 or higher.

Table 4: Performance of the elements by total and gender using R54 (For me) as the dependent variable. Only positive coefficients, 2 or higher, are shown.

TAB 4

The additive constant gives a sense of the percent of responses that would be 5 or 4 for vignettes that were empty, viz, absent elements. By design this is not possible, but the regression process can estimate this additive constant, which is typically considered to be a correction factor (Burton, 2021). Table 4 shows the additive constant to be about 46-47, suggesting that half of the time we can expect a rating of 4 or 5 for vignette or concept about elderberry wine, even when no elements to deeper detail.

Table 4 suggests that in terms of ‘interest’ (viz., For Me), a few elements perform strongly, and in fact elements that might not have been even thought of without the use of the AI-powered Idea Coach. These are ‘sensory testing’ for males, and ‘restaurant’ and ‘holographic labels’ for females. The benefit of creating elements with the assistance of AI is just this ‘out of the box’ thinking, with the researcher having the power to accept the suggestion or reject the suggestion by simple choice, and indeed to test the suggestion again in an easily run of the study with some new elements, new respondents.

Uncovering New-to-the-World Mind-Sets through Clustering

It is in the DNA of the scientific mind to look for basic causes, fundamentals of a situation. Although scientists and consumer researchers have attempted to develop profiles of archetypes, idealized profiles, these archetypes are too general, and fail to capture the granularity of everyday experience. Indeed, any attempt to divide people from the ‘top down’ is destined to fail because at the level of actual experience there are so many idiosyncratic factors that the archetypes simply do not have the ability to address [14].

The Mind Genomics approach works in the opposite direction, starting at the level of granular for a specific issue or situation, looking at the different dimensions of that granular situation, testing alternatives or expressions of each dimension, and then uncovering parallel groups of individuals or clusters for that situation. The clusters can be thought of as archetypes, not general ones, but archetypes of a specific situation, mind-sets in the language of Mind Genomics.

The statistics of Mind Genomics readily enable the researcher to discover these mind-sets, even without any ingoing knowledge. The approach simply creates individual level models of the type above shown for the total panel, or for any subgroup. Each individual generates a model, a model which is statistically valid because the 24 vignettes for each respondent had been created according to an underlying experimental design. The 24 vignettes are precisely arrayed to allow for OLS regression to be done on the data from each respondent. Each respondent produces 16 coefficients and an additive constant. Afterwards, the respondents are clustered by k-means clustering [15] first into two non-overlapping and exhaustive groups, (2-mindset solution), and then into three non-overlapping and exhaustive solutions (3-indset solution).

Clustering it follows purely mathematical criteria, e.g., minimize the sum of ‘distances’ between people in a cluster while at the same time maximize the distances between the centroids of the different clusters. It is left to the researcher to choose the number of clusters or mind-sets, and to name each cluster. Two good criteria are parsimony (fewer clusters are better), and interpretability (the clusters must tell a reasonably clear story).

For Mind Genomics studies, the measure of distance is the expression (1-Pearson Correlation). The Pearson Correlation coefficient measures the strength and nature of the linear relation between two sets of numbers, in our case the numbers coming from the 16 coefficients. The distance is small, viz., 0, when the Pearson correlation is +1 (1-1 = 0), occurring when the two sets of coefficients are parallel to each other. The distance is greatest, viz., 2 when the Pearson correlation is -1 (1 – 1 = 2), occurring when the two sets of coefficients go in precisely opposite directions.

Mind Genomics clustering usually reveals quite simple groups, the patterns often clear, ‘jumping out’ at the researcher. Table 5 shows the strong performing elements for the two and then the three mind-sets (abbreviated MS). The two mind-sets solution shows a very simple pattern, namely that which is familiar (venue for MS1 versus flavor for MS2). The three-mind-set solution is more intriguing, suggesting Label, Information, Venue, respectively. The three-mind-set solution is not perfect, since there are some strong-performing elements appealing to the mind-set slightly ‘off’ from the main interest of the mind-set.

Table 5 once again shows the ability of the OLS regression to uncover relevant coefficients, often coefficients which ‘make sense’ in their similarity to each other for a specific mind-set.

Table 5: Performance of the elements by total and both two and three mind-sets. gender using R54 (For me) as the dependent variable. Only positive coefficients, 2 or higher, are shown.

TAB 5(1)

TAB 5(2)

How Good are the Results?

Experienced researchers working in the world of inferential statistics and hypothesis testing measure their ‘performance’ by the likelihood that their hypothesis has not been falsified (Sprenger, 2011). The hypothetico deductive system of science is geared toward the creation, testing, acceptance/abandonment of hypothesis as the science moves slowly along. As famed scientist Max Planck opined ‘science advances one funeral at a time’ [16]. an experienced-based aphorism similar to the somewhat longer, more poetic but equally powerful idea from Tennyson’s Le morte d’Arthur “The old order changeth, yielding place to new, … Lest one good custom should corrupt the world “ (Sider, 2013).

With the evolution of research and its introduction into the world of education and application, the introductions often geared to ‘newbies’ (people without research experience), a common question is ‘how did we do?’. These newbies, students, others, do not have the wealth of experience, the years of data analysis, and the know-how about going to the extant ‘literature’ to compare their findings with what has been done. These newbies, aspiring researchers, need reinforcement about their work, e.g., a ‘score’ which tells them just how good their data are. In our over-measured society people use scores as an index of performance and a measure of growth.

One of the developments of Mind Genomics is the IDT, the index of divergent thought. The organizing principal underneath the IDT is that the positive coefficients, or more correctly the weighted positive coefficients, show how strongly the element ‘drives’ the rating. In other words, the IDT show how ‘on target’ the researcher has been by choosing elements to drive a dependent variable, that dependent variable here being ‘For Me.’

The IDT computations appear in Table 6. The total panel results account for 1/3 of the weight; the two mind-sets together account for 1/3 of the weight, and finally the three mind-sets together account for 1/3 of the weight. The stronger the performance of the coefficient for the total panel, the higher will be the IDT because that single high coefficient will in turn be multiplied by the value 0.33 for the total panel. In contrast, consider the value of that same high coefficient, but this time for MS 2 of 3, with 14 respondents, and a weight around 0.10. The contribution will be a lot lower. For this study the IDT is 46, reasonable. Unpublished values for the IDT in other studies have ranged from a high around to a low around 20.

Table 6: The IDT (Index of Divergent Thought)

TAB 6

Were the researcher to systematically vary aspects of the study and then measure the IDT for each aspect, the studies would move beyond informing about the world, and become a measure of the ‘impact’ of the different variables. Perhaps, most important for students is a measure of how well they understand the topic based upon the elements they select, the rating scale they use, the respondents they choose, and their experience as they iterate from one study to the next with clear human feedback. Much remains to be done.

Summarizing the Results Using Artificial Intelligence

The original objective of the study was to demonstrate the speed, power, and cost of Mind Genomics. As such, one of the goals was to see how quickly the key insights could be given to the reader in a format immediately ready for further efforts, including application or follow-on research. The first requirement was that the insight to be presented had to emerge in a robust way from the data, thus linking the insights to the actual experiment. The second requirement was that the insight had to be multifaceted, produced by clearly stated queries. The third requirement is that the insights had to be scalable, emerging from a few to many queries (many being > 10), with the insights emerging automatically. The effort stopped short of automatically creating a preliminary summarization document in the form of a ‘working paper’, but that next step is increasingly within reach. This first step to summarize the results used six queries provided to the AI program, with the instruction to look only at elements scoring +6 or higher for the subgroup.

The six summarization queries were submitted to the AI program, with the summarization done for each defined subgroup in the population, and done twice, once for the ‘TOP” (ratings 5,4 → 100), once for the ‘BOT’ (ratings 1,2→ 100). The defined subgroups were gender, age, response to the various questions in the self-defining questionnaire at the start of the study and finally to the two and the three mind-set solutions. Table 7 shows the summarization of the results for each of the three mind-sets for the TOP values (Rating 5,4, for ME).

Table 7: AI summarization of the three mind-sets

TAB 7

Discussion and Conclusions

The tradition of scientific research has become increasingly professionalized during the past centuries. What started out as the explorations of amateurs into a world hardly known has evolved into the world of science and academe that we know today., replete with societies, with journals, with the inevitable issue of who can publish what, and of course what exact constitutes publishable work. If that is not sufficient, the issues emerging involve the invisible networks of researchers who know each other and give each other help or in some unhappy cases just the opposite. And finally, there is the issue of funding research, funding publication and the need to survive the publish-or-perish world. In the words of an unnamed colleague, ‘we are all fighting for a sliver of the unpredictable funding pie.’

Within this world of discomfort and competitive behavior, the efforts of students, aspiring professionals, end up being crushed more often than not by an invisible college and rules of what makes science valid. All too often, the focus on being safe and correct ends up discouraging the researcher. Within this world, the Mind Genomics effort produces a system which expands the vision and hope of the amateur researcher, providing the potential of systematized, scientific, often even interesting exploration. It is within that spirit that this paper is presented, not so much as the convenient but hardly explored topic of elderberry wine as much as the exploration of what people just might do if given tools to empower their curiosity.

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Hyperuricemia and the Severity of Coronavirus Disease 2019 in Japan: A Retrospective Cohort Study – An Inseparable Relation with Hypertension and Chronic Kidney Disease

DOI: 10.31038/EDMJ.2023721

Abstract

Introduction: This study aimed to explore the impact of comorbid hyperuricemia on disease severity in Japanese patients with coronavirus disease 2019 (COVID-19). This retrospective cohort study included patients with COVID-19 between July 2020 and February 2021.

Methods: We divided patients into mild, moderate, and severe groups according to the degree of disease severity. Clinical and biochemical parameters on admission and comorbidities were compared between the mild and severe groups.

Results: We enrolled 146 patients in this study: 36 patients were allocated to the mild group, 96 to the moderate group, and 14 to the severe group. The male sex, age, body mass index (BMI), systolic blood pressure, pulse rate, white blood cell counts, levels of serum urea nitrogen and uric acid were significantly higher in the severe group than in the mild group (p<0.05), while lymphocyte counts and estimated glomerular filtration rate were significantly lower (p<0.05). As for comorbidities, malignant tumor, diabetes mellitus, hypertension, chronic kidney disease (CKD), hyperlipidemia, and hyperuricemia were associated with COVID-19 severity. Logistic regression analysis indicated that hyperuricemia was significantly positively associated with the severity of COVID-19 independent of age, sex, BMI, comorbidities of diabetes mellitus, and malignant tumor. However, the association between hyperuricemia and COVID-19 severity was eliminated by correction with hypertension or CKD.

Conclusion: These data suggested that comorbidities of hyperuricemia may indicate an increased risk of COVID-19 progression. Furthermore, patients with hyperuricemia comorbidities may require careful and intensive multidisciplinary treatment for hyperuricemia and hypertension and/or CKD to prevent progression of COVID-19.

Keywords

Chronic kidney disease, COVID-19, Hyperuricemia, Hypertension

Introduction

Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread worldwide, promoting the World Health Organization (WHO) to declare COVID-19 a pandemic and a public health emergency [1]. As of 29 May 2022, WHO reported over 526 million confirmed COVID-19 cases. Furthermore, over six million COVID-19-related deaths have been identified around the world [2]. The high contagiousness of SARS-CoV-2 and severity of COVID-19 are serious challenges of this infectious disease.

Several factors have previously been reported as severity risk factors of COVID-19, such as advanced age, obesity, hypertension, diabetes, smoking, malignancy, coronary heart disease, chronic liver disease, chronic obstructive pulmonary disease, and chronic kidney disease (CKD) [3-6]. Conflicting reports exists on the association between serum uric acid (UA) levels and severity of COVID-19. One study showed that hyperuricemia is an independent risk factor for COVID-19-related death [7], while another found that hypouricemia is positively associated with COVID-19 severity [8]. In addition, a U-shape phenomenon between serum UA levels and the COVID-19 severity has been reported [9]. The variability in the results of previous studies may be attributed to the fluctuation of serum UA levels at different times of measurement. Therefore, the aim of the current study was to investigate if and how comorbidity of hyperuricemia is associated with disease severity in Japanese patients with COVID-19.

Materials and Methods

Patients

This study was conducted at Tokyo Women’s Medical University Hospital, Tokyo, Japan. The institutional ethics committee approved the study protocol (approval #: 5612-R). In this retrospective cohort study, adult Japanese patients with COVID-19 admitted to Tokyo Women’s Medical University Hospital between July 2020 and February 2021 were included. The diagnosis of COVID-19 was confirmed when the result of a real-time reverse-transcriptase polymerase-chain-reaction assay for SARS-CoV-2 virus was positive. Information on clinical and biochemical parameters on admission and comorbidities were collected. The patients were divided into 3 groups based on the degree of COVID-19 severity: mild (negative computed tomography [CT] findings and saturation of percutaneous oxygen [SpO2] ≥ 94% on admission), moderate (positive CT findings or SpO2 <94% on admission), and severe (requirement of admission to the intensive care unit [ICU] or oxygen inhalation >10 L/h).

Data Collection

Data on patient characteristics, such as sex, smoking, alcohol use, and comorbidities were retrospectively collected from medical records. Clinical data were obtained on admission and laboratory data were obtained within the first 24 hours of admission. Additionally, clinical data such as body mass index (BMI), SpO2, blood pressure, and pulse rate were collected. BMI was calculated as a person’s weight in kilograms divided by the square of the height in meters. Blood cell counts, urea nitrogen (UN), alanine aminotransferase, UA, c-reactive protein (CRP), d-dimer, and creatinine were measured using standard laboratory methods at our clinical laboratory. The estimated glomerular filtration rate (eGFR) was calculated using the following equation: eGFR (mL/min/1.73 m2) = 194 × creatinine−1.094 × age−0.287 (×0.739, if female) [10]. The amount of oxygen required and admission to the ICU were retrospectively followed up during the hospitalized period from medical records.

Statistical Analyses

Data are expressed as the median with interquartile range (IQR). Baseline characteristics between the mild and severe groups were compared using the chi-squared or Fisher’s test. The correlation between UA level and the odds ratio (OR) for COVID-19 severity was investigated using Spearman’s rank correlation by calculating the OR using the following formula: OR = (true positive rate/false negative rate)/(false positive rate/true negative rate). Comorbidities were compared by logistic regression analysis between mild and severe groups and odds ratios for severity were calculated. Logistic regression analyses were subsequently applied to compare the strength of the relationship with the risk of COVID-19 severity between hyperuricemia and age, male sex, BMI, malignant tumor, diabetes mellitus, CKD, or hypertension. Patient characteristics, antiviral treatment, and outcome were compared between the patients with and without comorbidity of hyperuricemia using the Fisher’s test. Significance was defined as p<0.05. All statistical analyses were carried out using JMP pro version 15 (SAS Institute Inc., Cary, NC, USA).

Results

Patient Characteristics and Severity of COVID-19

Table 1 shows the characteristics of our COVID-19 patients upon admission who were classified into the mild (n=36), moderate (n=96), or severe group (n=14). Compared to those in the mild group, patients in the severe group were older, more likely to be men, had a higher BMI, systolic blood pressure, pulse rate, white blood cell counts, neutrophil counts, levels of serum UN, UA, and CRP, plasma d-dimer levels, and had lower lymphocyte counts and eGFR. Figure 1 reveals the scattergram showing the relationship between the serum UA level on admission and the OR for severe COVID-19. There was a positive linear correlation (R2=0.5285, p<0.0001).

Table 1: Characteristics of COVID-19 patients on admission

tab 1

Data are expressed as median (interquartile range), or n (%).
BMI: Body Mass Index; SpO2: Percutaneous Oxygen Saturation; sBP: Systolic Blood Pressure; dBP: Diastolic Blood Pressure; PR: Pulse Rate; bpm: Beats per Minute; WBC: White Blood Cell; LYMP: Lymphocyte; NEUT: Neutrophil; eGFR: Estimated Glomerular Filtration Rate; UN: Urea Nitrogen; ALT: Alanine Aminotransferase; UA: Uric Acid; CRP: c-Reactive Protein.
*p-value: comparing mild versus severe groups.

fig 1

Figure 1: Scattergram showing the relationship between serum uric acid level on admission and odds ratio for severe COVID-19.
R2=0.5285, p<0.0001.
COVID-19: Coronavirus Disease 2019.

Relationships between Comorbidities and Severity of COVID-19

Table 2 shows the comorbidities of the COVID-19 patients included in this study. Patients in the severe group presented a higher complication rate of diabetes mellitus, CKD, hypertension, and hyperuricemia than the mild group. There were no significant differences in the complication rate of liver disorder, heart failure, smoking, or alcohol use between the mild and severe groups.

Table 2: Comorbidities of COVID-19 patients

tab 2

Data are expressed n (%).
OR: Odds Ratio; CI: Confidence Interval.

Single correlation analyses showed that the serum UA level and comorbidity of hyperuricemia were significantly correlated with COVID-19 severity (Tables 1 and 2). Table 3 shows prevalences of comorbidities in patients with or without hyperuricemia. Prevalences of diabetes mellitus, CKD, heart failure and hypertension were significantly higher in patients with hyperuricemia than those without hyperuricemia. To determine whether the correlation between comorbidity of hyperuricemia and COVID-19 severity was independent of other factors, multiple regression analyses were conducted (Table 4). Comorbidity of hyperuricemia was significantly associated with COVID-19 severity independent of age (Model 1), male sex (Model 2), BMI (Model 3), comorbidity of malignant tumor (Model 4), and diabetes mellitus (Model 5), while the association between hyperuricemia and severity of COVID-19 was eliminated by correction with hypertension (Model 6) or CKD (Model 7). Table 5 shows relationships between COVID-19 severity and comorbidity of hyperuricemia in all patients, patients without hypertension or CKD. In all patients, the prevalence of comorbidity of hyperuricemia was significantly higher in the severe COVID-19 group than the mild COVID-19 group. However, the prevalence of comorbidity of hyperuricemia were not significantly different between the two groups when the patients were limited to those without hypertension or CKD.

Table 3: Comorbidities of COVID-19 patients with or without hyperuricemia

tab 3

Data are expressed n (%).
HU: Hiperuricemia; OR: Odds Ratio; CI: Confidence Interval.

Table 4: Comparison of the relationship between COVID-19 severity and comorbidity of hyperuricemia and other parameters.

tab 4

OR: Odds ratio; CI: Confidence interval; BMI: Body mass index

Table 5: COVID-19 severity and comorbidity of hyperuricemia in all patients, patients without hypertension or chronic kidney disease.

tab 5

HU: Hyperuricemia; CKD: Chronic Kidney Disease.
*p-value: comparing mild versus severe groups.

Relationships between the Comorbidity of Hyperuricemia and Treatment or Outcome of COVID-19

The treatment and outcome of COVID-19 was compared between patients with and without comorbidity of hyperuricemia (Table 6). Regarding treatment with antiviral agents such as favipiravir, ciclesonide, and remdesivir, treatment with favipiravir and remdesivir was significantly higher in patients with comorbidity of hyperuricemia than those without hyperuricemia. In addition, the rate of patients who had severe COVID-19 or died of COVID-19 was significantly greater in patients with comorbidity of hyperuricemia than those without hyperuricemia.

Table 6: Treatment and outcome comparisons between patients with and without comorbidity of hyperuricemia.

tab 6

Data are expressed as n (%).
HU: Hyperuricemia; COVID-19: Coronavirus Disease 2019.

Discussion

This study showed that patients with severe COVID-19 had a higher serum UA level (Table 1) and higher incidence of comorbidity of hyperuricemia (Table 2) than patients with mild COVID-19. Comorbidity of hyperuricemia was associated with the risk for severe COVID-19 independent of age, sex, BMI, comorbidity of malignant tumor, and diabetes mellitus (Table 4). However, the association between hyperuricemia and COVID-19 severity disappeared by correction with hypertension or CKD (Table 4), suggesting that as a risk factor of COVID-19 progression, comorbidity of hyperuricemia may be confounded by hypertension and/or CKD.

Hyperuricemia is more frequently observed in men and is caused by aging, obesity, alcohol and purine body intake, hypertension and reduced excretion due to kidney dysfunction [11]. These causes may overlap with known risk factors of COVID-19 severity such as male sex, advanced age, obesity, hypertension and CKD (5,6), while some reports showed that hypertension is not a risk factor for severe COVID-19 [12-14].

Previous studies have shown that hyperuricemia, hypertension, and CKD are inseparable, and that the relationship between hyperuricemia and kidney dysfunction is bidirectional [15]. The kidney eliminates 70% of the body’s daily UA production. CKD and hyperuricemia coexist because UA is excreted by the kidney and serum UA levels are negatively associated with GFR [15], while hyperuricemia is an early detection marker for renal dysfunction [16]. One possible mechanism by which hyperuricemia causes renal dysfunction may be via the formation of UA crystals in the renal tubules [17]. Hyperuricemia may also be involved in hypertension [18-21]. These strong associations among hyperuricemia, hypertension, and CKD may account for the phenomenon observed in our study where the relationship between hyperuricemia and COVID-19 severity was eliminated by correction with hypertension or CKD.

Furthermore, inflammation plays a key role in the relationship between UA and COVID-19 pneumonia. COVID-19 progresses to severe acute respiratory syndrome (ARDS) via hyperinflammation responses [22]. During ARDS, the abnormal generation of reactive oxygen species (ROS) occurs and causes organ damage [23] which may be counteracted by UA’s strong antioxidant capabilities [24]. A recent study reported a higher incidence of severe COVID-19 symptoms in individuals with low serum UA levels [8], suggesting that low serum UA levels may progress organ damage due to the reduction in ROS scavenging. High UA levels were also associated with a high incidence of severe COVID-19 [7]. Hyperuricemia is associated with systemic inflammatory markers and also higher CRP levels [25], both of which are observed in severe COVID-19 patients. Altogether, these findings suggest that both low and high serum UA levels are associated with severe COVID-19 [9]. In our study, serum UA levels were higher in the severe group upon admission compared to the mild group (Table 1); however, no U-shape association with UA and odds ratio for COVID-19 severity was observed (Figure 1).

UA levels upon admission may also be modified by dehydration and other factors. Favipiravir, an antiviral agent undergoing clinical trials for the treatment COVID-19 in Japan, is known to elevate UA levels [26]. We initially speculated that attending physicians may have hesitated to prescribe favipiravir in patients with hyperuricemia to avoid worsening both the condition and progression of COVID-19. However, this was not the case because the rate of patients treated with this agent was significantly higher in patients with comorbidity of hyperuricemia than those without comorbidity of hyperuricemia.

This study has some limitations. First, the study was conducted as a single center study and the sample size was relatively small. Second, owing to the retrospective cohort design of the study, we could not determine the causal relationship between hyperuricemia or comorbidity of hyperuricemia and COVID-19 severity; therefore, larger-scale prospective studies are needed to investigate this further.

Conclusion

Overall, we demonstrated that serum UA levels upon admission and comorbidity of hyperuricemia were associated with COVID-19 severity in Japanese patients, although the hyperuricemia comorbidity association was confounded by hypertension or CKD. These data suggest that comorbidity of hyperuricemia may indicate a risk of COVID-19 progression. Furthermore, patients with hyperuricemia comorbidity may require careful and intensive multidisciplinary treatment for hyperuricemia and hypertension and/or CKD to prevent progression of COVID-19.

Statements

Statement of Ethics

Study approval statement: This study protocol was reviewed and approved by Tokyo women’s medical university ethics committee, approval number 5612-R.

Consent to Participate Statement

Written informed consent was obtained by all the participants.

Conflict of Interest Statement

The authors have no conflicts of interest to declare.

Authorship

All authors (1) made substantial contributions to the study concept or the data analysis or interpretation; (2) drafted the manuscript or revised it critically for important intellectual content; (3) approved the final version of the manuscript to be published; and (4) agreed to be accountable for all aspects of the work.

Acknowledgment

We would like to thank the ward staff and doctors who cared for the patients enrolled in this study. We thank Editage (www.editage.com) for English language editing.

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Evaluation of the Fulfilment of the Therapeutic Objectives in Type 2 Diabetes People Attended in Primary Care Centres in Northwest Spain

DOI: 10.31038/EDMJ.2023714

Abstract

Objective: To know the degree of fulfilment of the treatment goals for DM2 patients.

Methods: Adult DM2 patients. Descriptive, observational and transversal design. Study variables: Process: % of patients with determination of BMI, abdominal perimeter, foot exploration, arterial pressure, EKG, ophthalmoscopy and HbA1c, lipid profile, microalbuminuria, glomerular filtration rate. Intermediate results: % of patients with overweight/obesity, active smokers, HbA1c value <7%, blood pressure <140/90, normal lipid profile, negative microalbuminuria. Final results: % of patients with foot ulcers, amputation, diabetic retinopathy, renal failure, coronary disease, cerebrovascular disease, peripheral arteriopathy and acute complications.

Results: The study include 1,029 DM patients 55% male, mean age 67 ± 0.8 years old. The % of patients with overweight, obesity, hypertension, dyslipemia, were 32.5%, 59.4%, 63.8%, and 64% respectively. The 94% have HbA1c determination, 47% ophthalmoscopy, while only 2.2% foot examination. The percent of patients with <HbA1c, blood pressure <140/90, normal lipid profile, and active smokers were 72.6%, 54.5%, 50% and 26% respectively. While 11.5%, 5%, 3.5%, 2.1% and 8.6% had cardiovascular disease, ictus, peripheral arteriopathy, foot ulcers and renal failure respectively.

Conclusions: The present study shows that in the primary care centers in northwestern Spain, a high percent of patients had good metabolic control and almost all the objectives of the treatment for patients with DM2 are met except the examination of the feet. Actions need to be promoted in order to meet the mentioned objective, including recording educational activities.

Keywords

Type 2 diabetes, Primary care centers, Compliance therapeutic objectives

Introduction

Type 2 diabetes mellitus (T2DM) is a chronic and progressive disease with high prevalence in the general population worldwide. In Spain, the Di@bet.es study [1] estimated the prevalence of DM at around 13.8% in the adult population, with 43.5% of cases not known. DM2 is associated with high morbidity and mortality due to associated vascular disease, both microvascular (retinopathy, nephropathy and neuropathy) and macrovascular disease (cerebral stroke, peripheral arthropathy and ischemic heart disease) [2]. Several years before the diagnosis of T2DM, there is already endothelial dysfunction, insulin-resistance and hyperinsulinemia in patients with DM2, factors that accelerate atherogenesis [3,4]. Therefore, since the main cause of mortality in patients with T2DM is cardiovascular disease, many clinicians think that T2DM is a cardiovascular disease [5]. In addition, T2DM is associated with factors that increase the risk of cardiovascular disease such as obesity, hypertension and dyslipidemia [6]. The UKPDS study showed that intensive glycemic control in people with type 2 diabetes reduced the incidence of microvascular disease, but macrovascular disease did not [7]. For all the above, patients with DM2 in addition to glycemic control require treatment of other cardiovascular risk factors. Several studies in Spain have observed a high percentage of patients with DM2 with poor glycemic control [8,9]. Previous studies have shown that the prevalence of cardiovascular risk factors is higher in long-term patients compared to newly diagnosed patients [10] and that their control was insufficient [11]. More recent studies show that this situation persists [12] or shows slight improvement [13].

The objective of this research was to know the degree of compliance with the treatment objectives of patients with DM2 treated in primary care centers in Northwestern Spain, with special emphasis on the degree of metabolic control and classic cardiovascular risk factors or comorbidities.

Subjects and Methods

The present is a cross-sectional descriptive observational study, which includes a randomized sample of patients with DM2, treated and followed by Primary Care (PC) physicians from the health area of Vigo, territory of southern Galicia, autonomous community of northwestern Spain.

The population of the Vigo Health Area, according to the Municipal Register of Inhabitants of January 1, 2017, was 608,841 inhabitants, of which 48.3% were men and 51.7% women. Of these, 511,724 were over the age of 18. In the computerized registry of the health area, Electronic Medical Record of Galicia (IANUS), there were 41,450 patients with DM2 over 18 years of age. Therefore, the target population includes the aforementioned 41,210 that met the inclusion criteria: Reside in the Vigo area, at least 12 months before the start date of the study, be over 18 years old, be type 2 diabetics receiving antidiabetic treatment. 240 were excluded from the study because they had some exclusion criteria: Patients with diabetes 2 who have not attended their nursing doctor in the last year. Immobilized or bedridden patients. Terminal patients (metastatic cancer, terminal heart failure, highly advanced COPD). Advanced dementias.

Sampling and Calculation of Sample Size

We want to estimate the prevalence of good control of diabetes mellitus and set up a cohort for monitoring micro- and macro-vascular events. With an estimated number of people with diabetes in the Vigo Area of 41,000, for an event ratio of 20%, and with an error of ±3% in the estimation and a confidence level of 95% (alpha=0.05), the necessary number of subjects to study was 672. Estimating data losses of 15% of the total, 773 patients would have to be selected. From the database of Electronic Medical History of Galicia (IANUS) a list was prepared, which included patients who included the episode or clinical problem of diabetes or who had prescribed an antidiabetic drug.

Once the list was cleaned, the sample of patients was randomly selected with replacement.

Study Variables

The study aims to obtain information on the different aspects of the follow-up and control of patients with type 2 diabetes in Primary Care:

Variables of Process

Body Mass Index (BMI) assessment in the last year. Assessment of the Abdominal Perimeter (BP) in the last year. Existence of two determinations of glycohemoglobin (Hb1Ac) in the last year. Performing an electrocardiogram (ECG) in the last year. Measurement of blood pressure in the last year. Measurement of blood pressure in the last year. Realization of a lipid profile in the last year. Determination of glomerular filtration rate and microalbuminuria in the last year. Existence of an eye fundus or ophthalmologist consultation in the last 2 years. Diabetic foot assessment in the last year. % correctly vaccinated against influenza and pneumococcus.

Intermediate Variable

Percentage of patients with obesity or overweight (BMI > 25 Kg/m2). Percentage of patients Smokers in the last year, percentages of patients with adequate HbA1c levels (HbA1c <7%), percentage of patients with controlled blood pressure in the last year (Blood Pressure ≤140/90), percentage of patients with good lipid control in the last year (LDL<100), percentage of patients with normal glomerular filtration rate (>60 mi/min) in the last year. Percentage of patients with negative microalbuminuria in the past year.

Final Outcome

Percentage of patients with foot ulcers, amputees, diabetic retinopathy, renal failure, coronary heart disease, cerebrovascular disease, peripheral artery disease, or acute complications (hospitalizations for hypoglycemia or hyperosmolar coma).

Statistical Analysis

For the analysis of the data, the statistical package SPSS v19.0 (SPSS, Chicago, IL) and the Epidat v4.2 package were used. Initially, a descriptive analysis of all the variables recorded in the study was performed. The numerical variables will be described by mean and standard deviation if they have normal or median distribution and quartile deviation if they do not. Categorical variables will be described by absolute frequency and percentage.

The numerical variables will be compared using the t-student test or the non-parametric Mann-Whitney U test. Categorical variables were compared using the chi-square test or Fisher’s exact test. Multivariate binary logistic regression analysis was performed to describe the variables associated with good diabetes control, establishing this as a dichotomous variable.

Ethical and Legal Aspects

The study was conducted according to the standards of good practice in research. During the preparation of this study, the fundamental principles of the Declaration of Helsinki and the Oviedo Convention of the Council of Europe on Human Rights and Biomedicine, as well as all existing legislation, were respected. The current legislation was complied with at all times (Law 3/2001, of March 28 -modified by Law 3/2005 of March 7-, regulating informed consent and the rights of patients and Decree 29/2009, of February 5, which regulates the use and access to electronic medical records) and no personal identification data will be included in the data collection notebook (CRD), that will be dissociated, so the analysis will be carried out in a completely anonymized way, the subjects cannot be identified, in accordance with Organic Law 15/1999, of December 13, on the Protection of Personal Data.

Results

The sample of patients studied was 1,029 people with DM2, 55% of who were males, the mean age of the patients was 67± 0.8 years, being significantly higher in women (Table 1). Thirty-two point 5% of the patients were overweight and 59.4% obese. Sixty-three point eight % of patients were hypertensives and 64 % had dyslipidemia, 26% were active smokers and 20% were former smokers (Table 1).

Table 1: Main characteristic of the sample of T2DM patients

Sample characteristics

Number of patients 1029
Men (n/%) 563/55 P<0.001
Women (n/%) 466/45
Age (years) 67 (±0.8)
Men 6.4 (±1.0) P<0.001
Women 69.0 (±1.1)
HbA1c mean (%) 6.7 (±0.1)
BMI (kg/m2) 31.5 (±0.4)
Men (kg/m2) 31.1 (±0.25) p: 0.03
Women (kg/m2) 32.0 (±0.34)
Normal weight (%) 8.1
Overweight (%) 32.5%
Obesity/BMI 30-39 (%) 54.3%
Morbid obesity/IMC ≥40 (%) 5.1%
Hypertension (%) 63.8 (±3.0)
Dyslipidaemia (%) 64.2 (±3.0)
Total cholesterol (mg/dl) 183. 0 (±2.6)
LDL-cholesterol (mg/dl) 105.4 (±2.2)
HDL-chol (mg/dl) 48,7 (±0,8)
Triglycerides (mg/dl) 151.0 (±6.3)
Smoking (%)
Non smoker 54 (±4.1)
Former smoker 20 (±2.9)
Smoker 26 (±4.2)
Ischemic heart disease (%) 11.5 (±1.9)
Stroke (%) 5.0 (±1.5)
Peripheral arterial disease (%) 3.5 (±1.3)
Heart failure (%) 5.4 (±1.6)
Renal insufficiency (%) 8,6 (±1,9)
Creatinine (mg/dl) 0.92 (±0.4)
Glomerular filtration (ml/min) 79.2 (±1.0)
Alb/Cr urine > 30 mg/gr (%) 33.8 (±2.9)
Foot ulcer (%) 2.1 (±0.7)
Cancer (%) 10.2 (±1.8)
Mental illness (%) 8.4 (±1.8)
Thyroid disease (%) 7.1 (±1.7)

Regarding the process indicators, 94% of the patients had at least 2 HbA1c determinations in their history, while 47% of the patients had undergone ophthalmological examination in the last 2 years, 40.6% had registered body weight control, while the examination of the feet was the indicator of lower compliance in only 2.2% of the patients (Figure 1).

fig 1

Figure 1: Fulfillment of the process objectives (%)

Regarding the intermediate outcome indicators, 72.6% of patients had mean HbA1c values lower than 7% (Table 2), good blood pressure control 54.5%, with 26% of the sample being active smokers, while good control of dyslipidemia was evident in about 50% of patients (Figure 2).

Table 2: Degree of glycemic control and its relationship with the number of antidiabetic drugs used

HbA1c

% of patients

Number of antidiabetic drugs

< 6.5% 57.0 (±3.0) 0.9 ± 0.7
6.6 -7% 17.9 (±2.6) 1.2 ± 0.7
7.1 – 7.5% 7.1 (±1.8) 1.6 ± 1.1
7.6 – 8% 5.4 (±1.6) 1.8 ± 0.8
>8% 12.6 (±2.4) 1.8 ± 2.6
P < 0.001

fig 2

Figure 2: Fulfillment of the intermediate objectives (%)

Most patients had their blood pressure monitored by determining clinical blood pressure (Table 3).

Table 3: Degree of blood pressure control in the whole sample of patients

%

SBP day mmHG

DBP day mmHG

SBP night mmHG

DBP night mmHG

Good daytime control %

Good night control %

ABPM 8,4 (±1,8) 138,6 (±4,1) 83,0 (±2,6) 125,7 (±4,7) 72,9 (±3,1) 52 (±10,3) 81,2 (±7,1)
SMPM 3,5 (±1,2) 139,2 (±5,7) 83,6 (±2,9) 36,7 (±15,8)
CBP 87,3 (±1,9) 135,6 (±1,1) 79,2 (±0,7) 54,5 (±3,2)

ABPM: Ambulatory blood pressure monitoring, CBP: Clinical blood pressure, DBP: Diastolic blood pressure, SBP: Systolic blood pressure, SMBP: Self-monitoring blood pressure.

Finally, with regard to the final indicators, 11.5% of our patients had ischemic heart disease, 5% stroke, 3.5% peripheral artery disease, foot ulcers in 2.1% and 8.6% renal failure (Table 1).

Another objective of the present study was to know the frequency of the different vascular risk factors. Dyslipidemia and hypertension were the most prevalent factors, 64.2% and 63.8% respectively, followed by obesity in 59% of cases and active smoking in 26.1%. 14% of patients had 3 or 4 CVR factors in addition to diabetes (Table 4).

Table 4: Presence of cardiovascular risk factors (CVRF) in the sample of T2DM patients

CVRF

%

Diabetes 100.0
Hypertension 63.8 (±3.2)
Dyslipidemia 64.2 (±2.8)
Obesity 59.0 (±3.0)
Smoking 26.1 (±3.9)
Diabetes +
1 CVRF 34.8 (±3.2)
2 CVRF 37.6 (±2.4)
3 CVRF 13.0 (±2.0)
4 CVRF 1.0 (±0.8)

Discussion

In the present observational, descriptive and cross-sectional study, a representative sample of patients with DM2 treated in the health area of northwestern Spain was obtained through the random selection of patients with DM2, these data being similar to those found in previous studies in our country [9-13]. The objectives of the study were to know the main socio-demographic and clinical characteristics of patients with type 2 diabetes mellitus (DM2), as well as to obtain information on the degree of compliance with the parameters of the treatment protocol and follow-up of patients attended in primary care centers in the health area of Vigo, with special emphasis on the degree of metabolic control and classic cardiovascular risk factors or comorbidities.

The pillars in the treatment and prevention of comorbidities in patients with T2DM are based on lifestyle changes, pharmacotherapy and education. The available evidence suggests that intensive treatment, mainly from the moment of diagnosis, is effective in preventing microangiopathic complications and cardiovascular events [14].

The variables analyzed in this study are the indicators of quality of care in diabetes mellitus recommended by the Network of Diabetes Study Groups in Primary Health Care (redGDPS) [15], based on the Declaration of Saint Vincent [16]. The comparison with previous studies carried out in our country showed greater compliance with respect to HbA1c measurements, similar results on eye fundus examination, and lower compliance with weight control, and especially with systematic examination of the feet [11,15,17-19]. As the authors of the guide of the GDPS network point out, the indicators are not a direct measure of quality, but allow to detect problems that require an in-depth analysis, in this case the reason for the low compliance of the foot scan.

Compared to the aforementioned studies [15,17-19], there was a clear improvement in glycemic control, while hypertension control was slightly lower, and control of dyslipidemia and smoking habits frankly improvable. Only 6.6% of our patients had a correct comprehensive control, which included glycemic control and the rest of CVRF. In this sense, it should be noted that 72.4% of patients had 1 or 2 associated cardiovascular risk factors and only 14% 3 or more risk factors.

The frequency of macrovascular and microvascular complications was similar to that of previous studies, with less frequent ulcerated lesions on the feet.

The frequency of dyslipidemia and hypertension was lower than that observed in two recent studies conducted in Catalonia and Cantabria health areas in Spain [20,21]. While the frequency of obesity and smoking habit was higher [11,20,21]. The results indicate some improvement, but still far from desirable for our patients. A factor that may condition the comparability of different studies is the fact that the frequency of risk factors depends on the time of evolution of diabetes [10].

The main limitation of the present research is that the study is cross-sectional and we cannot analyze the evolution of the degree of compliance with the treatment objectives in the same sample of patients, however, since the selection of patients has followed a rigorous selection process, it makes the sample representative of the patients seen in our Primary Care Centers, and the review of the history represents an audit of our work, which allows us to draw conclusions about the aspects that we must improve.

In conclusion, our study shows that in the health area of Vigo, a high percentage of patients have good metabolic control and generally meet the treatment objectives, But with regard to the continuous improvement of the quality of the care process, in the section on process indicators, specifically the annual examination of the feet, it is necessary to introduce actions that improve this parameter, as well as the registration of educational interventions and achieve a decrease in the percentage of patients with obesity and active smokers.

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