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Research Article – Cancer Stud Ther J

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Tobacco Smoking, the Meeting Point of Health Issuesof the 21st Century

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DOI: 10.31038/CST.2024941

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024934

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Short Review – Cancer Stud Ther J

DOI: 10.31038/CST.2024933

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024932

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024931

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Research Article – Cancer Stud Ther J

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Commentary – Cancer Stud Ther J

DOI: 10.31038/CST.2024923

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Research Article – Cancer Stud Ther J

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High XPO1 Expression can Stratify Gastric Cancer Patients with Poor Clinical Outcome

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024921

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Berkeley, Anti-Semitism, and AI-Suggested Remedies: Current Thinking and a Future Opportunity

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024913

Three AI-synthesized Mind-sets of Patients Talking to Their Surgeon about a Prospective Operation for Different Types of Diagnosed Cancer

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024912

Programming of Transcription (POMC) and HPA Responses to Stress

Robert Dubnik

Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2024911

Plasticity of Pancreatic Acinar Cells-Lesson from Hpa2- KO Mice

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DOI: 10.31038/CST.2023834

Prostate Cancer Prediction and Detection Using Hybrid CNN-Deep Learning Techniques

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2023833

RGCC Promotes Adipocyte Thermogenesis by Modulating Pgc1α Expression

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Review Article – Cancer Stud Ther J

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Review Article – Cancer Stud Ther J

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Research Article – Cancer Stud Ther J

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Ambivalent and Conjectural-Synovial Sarcoma

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Editorial – Cancer Stud Ther J

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Review Article – Cancer Stud Ther J

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Continuation of Temozolomide Chemotherapy in a Glioblastoma Patient After Resolution of COVID-19 Infection

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Case Report – Cancer Stud Ther J

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Research Article – Cancer Stud Ther J

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Reporting and Journalistic Ethics as an Ecological Issue in Contemporary Times

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Research Article – Cancer Stud Ther J

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Role of Alpha Fetoprotein in Hepatocellular Carcinoma

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Short Commentary – Cancer Stud Ther J

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Audit on Incidences of Oxaliplatin Induced Hypersensitivity Reactions during Infusion in Day Care Oncology at a Tertiary Care Hospital, Karachi, Pakistan

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Review Article – Cancer Stud Ther J

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Review Article – Cancer Stud Ther J

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Learning US Assisted Neuraxial Technique during a Pandemic: Case Report

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Review Article – Cancer Stud Ther J

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Research Article – Cancer Stud Ther J

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Review Article – Cancer Stud Ther J

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Opinion Article – Cancer Stud Ther J

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Research Article – Cancer Stud Ther J

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Research Report – Cancer Stud Ther J

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Research Report – Cancer Stud Ther J

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Huge Retroperitoneal Mass: Ginecologic-Type Leiomyoma

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Case Report – Cancer Stud Ther J

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Psychological Responses of Patients Receiving a Diagnosis of Adenocarcinoma

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Case Report – Cancer Stud Ther J

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Review Article – Cancer Stud Ther J

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A Comment on Nuclear Safety and Radiation Protection from a Historian of Science

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Short Commentary – Cancer Stud Ther J

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Effects of a Symbiotic on the Quality of Life of Elderly Patients with Breast Cancer: a Randomized Controlled Pilot Trial

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Research Article – Cancer Stud Ther J

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Incidence and Factors of Prolonged Postoperative Ileus in Gastric Cancer Surgery

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Research Article – Cancer Stud Ther J

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The Prognostic Value of Lymphocyte-to-Monocyte Ratio and Nutritional Index for Ovarian Cancer Patients with Normal CA125 Level

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Research Article – Cancer Stud Ther J

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Marking with a Dye to Visualize the Limits of Resection in Breast Conserving Surgery

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Research Article – Cancer Stud Ther J

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Smaller and Small: Strategies to Iterate to Knowledge about the Granular Aspects of Donations

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Research Article – Cancer Stud Ther J

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Current Utility of Chimeric Antigen Receptor T-Cell Therapy in Non-Small Cell Lung Cancer

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2020542

Dosimetric Comparison and Clinical Toxicity in Cervical Cancer Patients Treated with Intensity- Modulated and Three-Dimensional Conformal Radiotherapy: Real-World Data

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Research Article – Cancer Stud Ther J

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CAR-T Neurotoxicity Causing Severe Brain Oedema and Tonsillar Herniation in a Young Child with Relapse ALL – A Case Report

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Case Report – Cancer Stud Ther J

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Recurrent Gallbladder Cancer Presenting as Ovarian Neoplasm: A Case Report

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Case Report – Cancer Stud Ther J

DOI: 10.31038/CST.2020533

Convalescent Plasma Therapy for COVID-19

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2020532

Management of Cancer Patients Undergoing Radiation Therapy during the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: A Review of the Literature

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Review Article – Cancer Stud Ther J

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Towards COVID-19 Prophylaxis: An AIDS Preclinical Research Perspective

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Perspective – Cancer Stud Ther J

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COVID-19 and Oncological Health Workers: Psychological Reactions and Interventions

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Review Article – Cancer Stud Ther J

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ACBD3, Its Cellular Interactors, and Its Role in Breast Cancer

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2020523

Practice and Reflection on the Ethical Review on Covid-19 Pandemic

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2020522

Trials of Low Dose Cytostatic Drugs in Severe Covid-19 Should Be Considered

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Editorial letter – Cancer Stud Ther J

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Gastrointestinal Clear Cell Sarcoma Tumour of the Caecum: Case Report and Review Literature

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Case Report – Cancer Stud Ther J

DOI: 10.31038/CST.2020514

Heparan Sulfate-Modifying Enzymes: Intriguing Players in Cancer Progression

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Short Commentary – Cancer Stud Ther J

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The Anger Felt by Cancer Patients. It Could Be An Unexpected Obstacle To The Treatment Path?

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Research Article – Cancer Stud Ther J

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The Addition of Valproic Acid to Concurrent Radiation Therapy and Temozolomide Improves Patient Outcome: A Correlative Analysis of RTOG 0525, SEER and A Phase II NCI Trial

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Research Article – Cancer Stud Ther J

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A Perspective: Regulation of Ku70 Cytosolic Function

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Perspective – Cancer Stud Ther J

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Disseminated Tumor Cells in Bone Marrow In gastric Cancer Patients with Obesity

Bubnovskaya L, Ganusevich I, Merentsev S and Osinsky D

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019452

Hedyotis diffusa and Indigo naturalis lack of clinical evidences for the anti-leukemia efficacy but possess gastrointestinal, hepatic, and kidney toxicity (白花蛇舌草和青黛缺乏抗白血病的临床证据且有胃肠道和肝肾毒性)

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Research Article – Cancer Stud Ther J

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CD44 cleavage product CD44-intracellular domain regulates gene transcription and tumorigenesis

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Mini Review – Cancer Stud Ther J

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New Directions in Cancer Therapy – Peptide Targeting Therapy

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Mini Review – Cancer Stud Ther J

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Renal Mucinous Tubular and Spindle Cell Carcinoma: A Report of Two Cases and Literature Review

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Case Report – Cancer Stud Ther J

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Metastatic Prostate Cancer to the Renal Pelvis and Proximal Ureter: A Case Report and Review of the Literature

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Case Report – Cancer Stud Ther J

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Nucleolin: a prognostic marker in cancer?

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Commentary – Cancer Stud Ther J

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Open Space Knowledge and Data and Their Influence on Natural Products Based Self-Medication Trends

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Mini Review – Cancer Stud Ther J

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Patient-oriented Biobanking for Cancer Research

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Commentary – Cancer Stud Ther J

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Quantitative Imaging Features of Habitats in Soft Tissue Sarcomas are Associated with Treatment Response: A Pilot Study

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Research Article – Cancer Stud Ther J

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Ribosomal S6 Kinase 2 Promotes Survival of Triple- Negative Breast Cancer Cells to Apoptotic Stimuli

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019432

At Doctor Level

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Letter to The Editor – Cancer Stud Ther J

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Diagnosis of CLABSI from Blood and Needleless Connector Cultures in Patients with Acute Leukemia: a Prospective Cohort Study

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Research Article – Cancer Stud Ther J

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Immune Cytokines for Cancer Therapy

Payal Grover, Juliana J Cui, Yibai Wang, and Hongtao Zhang

Research Article – Cancer Stud Ther J

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PD-1 Inhibitors: To Go or To Stop? ; Review Articles

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019423

Usability Testing of the Online Stress Management Intervention (STREAM) for Cancer Patients: Results and Implementations

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019422

MN Virus

Raja Tounsi

Short Communication – Cancer Stud Ther J

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Health Threats Awareness – Responses to Warning Messages about Cancer and Smartphone Usage

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019415

The Positive Effect of Skd Plus Iot and Hbo2t In The Treatment Of Cancer [Introducing Sorush Cancer Treatment Protocol (Sctp)]

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019414

Skin Cancers in Albinos at Surgical Oncology Unit of Donka National Hospital (Conakry)

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2019413

Development of Synthetic Cell Differentiation Agent Formulations for the Prevention and Therapy of Cancer via Targeting of Cancer Stem Cells

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Research Article – Cancer Stud Ther J

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Might Actinomycin be Used to Cure All Cancer?

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Letter to the Editor – Cancer Stud Ther J

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On the Threshold: What Concerns Healthy People about the Prospect of Cancer?

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018345

Increasing Vigilance by Second Observer during Colonoscopy Improves Adenoma Detection Rate

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018344

A Parallel Computation Approach to Detailed 3D Modelling of the Complete Oxygen Distribution in Large Tumours

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018343

Single versus Double Chest Tube Drainage after Thoracotomy for Cancer

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018342

Dichloroacetate (DCA) as an Oncology Chemotherapeutic Agent – What’s all the Hype and is it Warranted?

Sherry A Bradford and Akbar Khan

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018341

Results from application of scripted based, algorithmic approach to multi-target SRS planning, evaluation and characterization of volume dependent metrics

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018335

Liver Honeycomb Sign

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Case Report – Cancer Stud Ther J

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The impact of P-glycoprotein and Midkine on Paclitaxel / Cisplatin Chemoresistance in Ovarian Cancer

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018333

Tamoxifen, Uterine Corpus Cancer and Breast Cancer

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018332

Diagnostic Value of Cytotoxic Natural Killer Subpopulations in Malignant Pleural Effusions

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018331

Integrin Inhibition in the Tumor Microenvironment – more complex than expected

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Review Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018323

Assessing the Radiation Doses Received by Patients Undergoing Mammography Imaging at Mulago National Referral and Teaching Hospital

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018322

The Akt signaling pathway in skin cancer cell lines treated with RRM-MV, a short peptide analogue of the MT5 protein of myxoma virus

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018321

Osteosarcoma of Eighth Rib: A Case Report

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Case Report – Cancer Stud Ther J

DOI: 10.31038/CST.2018313

Cushing’s Disease (Micro-Adenoma) Associated with Sudden Blindness in a Dog

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Case Report – Cancer Stud Ther J

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Reduced Burden of Chemotherapy Side-Effects in Patients Receiving Inositol Hexakisphosphate Alone or In Association with Myo-Inositol

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2018311

Response to Induction Therapy Confers a Significant Survival Benefit in Patients with Resected T4 Non-Small Cell Lung Cancer

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017283

Conflict of Clinical and Public Health Viewpoint in Colorectal Screening

Döbrössy L

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017282

Potential Molecular and Cellular Mechanisms Underlying the Anti-Inflammatory and Anti-Tumor Properties of Probiotics: Our Experience

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Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017281

Useful Anti-Cancer Agents of Natural Product Origin

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Research Article – Cancer Stud Ther J

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A Novel Approach to Ameliorate and Provide a Protective Role in Neurodegenerative Diseases by a Novel Peptide, TFP5/TP5, Derived from Cdk5 Activator p35

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Short Communication – Cancer Stud Ther J

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Androgen Deprivation Therapy and Cardiovascular Risk

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Research Article – Cancer Stud Ther J

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Sexuality in Patient with Breast Cancer Hospitalized in Professional Nursing Vision

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Research Article – Cancer Stud Ther J

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An advanced biospecimen biobanking monitoring system in the development and implementation of chondrocyte and cartilage tissue banking informatics tools for intra and inter-bioinstitutional translational autologous advanced cell therapy, cryopreservation and medicine research

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Research Article – Cancer Stud Ther J

Subject-specific prediction using nonlinear population modeling: application to Monte Carlo simulations will change the way we treat patients with Matrix-induced autologous chondrocyte implantation (MACI) in the knee

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Research Article – Cancer Stud Ther J

CartiCaroGenea®-AM: A Mesenchymal stem cells derived chondropoietic Autologous Cartilagenous Treatment for patients with cartilage defects validated of a dose warping algorithm using clinically realistic scenarios

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Human developmental chondrogenesis as a basis for engineering Chondrocytes-Specific Expression of RANKL/OPG Osteoprotegerin Modulates Osteoclast Formation in Metaphyseal Bone utilizing the NetworkPainter: A dynamic in silico flow cytometry reconstructive approach based on an intracellular pathway animation in Cytobank

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CARTILOREGENEATM®-AU: An autologous chondrocyte-induced mesenchymal stem cell living cell transplant for the treatment of the cartilage defects on translating cartilopoeitic protein networks as evolutionary benchmarks of cartilo-protein interactions for the evaluation of stem dosimetric dosage clustering algorithms

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico Computational re-modeling of the mechanical cartilage modulation in the growth plate by sustained ex vivo effected high frequency electric field on quantum imaging enhancement of chondrogenesis in PGLA scaffolds loaded chondrocytes. A TNF accelerated driven Death of Mandibular Condyle via interleukin-1β/nerve growth factor signaling

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico combinatorial approach towards the design of nanofibrous scaffolds for chondrogenesis utilizing a transaxial analysis of the development of a 3D-Printed construct consisting of sox-9 igf-1 Cotransfected human chondrocytes as a hybrid living transplant for Cartilage Tissue Regeneration for the enhancement of the synthesis of cartilage matrix components collagen-II and glycosaminoglycans. A combined experimental measurement for the investigation of articular cartilage and chondrocyte response to collagen ABS/PLA scaffold loading

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico prediction of an optimum dosimetric combination of DMSO, carboxylated ε-poly-L-lysine cryoprotectant agents with minimum Thermal Conductivity Differences between the Crystalline and Vitrified States with Applications to Cryopreservation on Efficient production of live autologous cartilage derived chondrocytes vitrified with optical properties of water soluble CdSeS nanocrystals using glycerin as terminal stabilizing agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico axisymmetric multistage model of linear biphasic mesenchymal stem cell and chondrocyte protein secreted-matrix interactions for the reconstruction of the dynamic mechanical environment of a time varying magnetic field expanded chondrocyte biphasic finite elemental model in articular cartilage for the evaluation of the ability of natural and synthetic scaffolds in providing an appropriate environment for growth and sustain of the chondrogenic capacity of de-differentiated of cartilage-derived L-lactic glycolic acid (PLGA) loaded chondrocytes for and then for autologous transplantations

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Computer-Aided meta-analyses reveal Accelerated weightbearing rehabilitation and time-dependent differences between the clinical outcomes achieved by microfracture and mesenchymal stem cells induced implantation of PolyScaffolding based Matrix-induced autologous chondrocyte implantation (POMACI) for chondral defects in the patellofemoral joint after matrix-induced autologous chondrocyte implantation in the tibiofemoral joint: early clinical and radiological outcomes

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Bayesian prediction model between a biomarker and the clinical endpoint for dichotomous Improvements of outcomes after an autologous cartilage tissue implantation, compared with microfracture for treatment of distal femoral cartilage lesions

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

ArthroCartiGenea®-AR: A Mesenchymal stem cells Co-Cultured Chondrocytes Comprising Chondrogenic Autologous Treatment for patients with Osteoarthritis and large Cartilage defects on assessing the Clinical Impact of Approximations in Analytical Dose Calculations for Advanced Cell Therapy

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico designed Fusion Inhibitor consisting of five cancer filtered conserved pharmacophoric chemical fragments with Greatly Promising Pharmaco-Mimic Properties to a Rationally Engineered Wilms’ Tumor Peptide as a future computer generated hyper-molecule for the potential treatment of the acute myeloid leukemia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A predicted chemo-polypharmacophoric agent comprising (Propeptide-Fc)/MGF peptide mimicking interactive of high free binding energy properties towards Wnt7a/Fzd7 signalling Akt/mTOR anabolic growth IGF-I/PI3K/Akt -I/MAPK/ERK pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A mechanistic in silico molecular recognized approach for the ligand based generation of a dual N-formyl-Met-Leu-Phe (fMLP), and MMK-1peptide mimetic hyper-agonist fMLP targeted receptor against the PGE2 EP4 pathway chemotherapy-induced alopecia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A rational in silico drug-target flexibility complement methodology-design for the generation of a peptide-mimic novel pharmacoelement binding to the amino acid conserved sequences of the active loop of a Haemophilus influenzae porin P2

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Computer-aided rational approach for the in silico generation of a TCR Peptide Mimetic Pharmacoligand as a potential chemo-modulator in Human Autoimmune Diseases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a web server multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Rational Design and Optimisation of a Bioactive Cyclic mimetic-Peptide Pharmacophoric hyperagonist for the in silico Generation of a Down-Regulator of TNF Secretion by Investigating Drug-Target Association and Dissociation Mechanisms

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Rationally designed of Polycystin-1 and Gα12 poly-mimic pharmacophoric agents as a potential in silico generated by a chemocoring prediction assay of a synthetic multi-targeted motif-like mimetic peptide regulator for the cleavage of E-cadherin in kidney epithelial cells

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A computer simulated gp100 Peptide mimic designed pharmacophore as a Vaccine-like and Interleukin-2 in silico generated superagonist with potential clinical effect in Patients with Advanced Melanoma using an Improved Algorithm for Chemically Tractable, Semi-Automated Protein Inhibitor Design

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Computational Assay to Design an Epitope-Based Mimo-Peptidic hyper agonist consisting of linked active Pharmacophoric chemo-Scaffolds comprising in silico demonstrated vaccine-like potential properties against Saint Louis Encephalitis Virus conserved binding domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico chemoproteomic prediction-scan for the generation of a tyrosinase aa95-104FMGFNCGNCK antigenic patternLFA-3/IgG fusion polypeptide IleAlaArgArgPheLeuOH (Kinetensin) mimetic pharmacophore on conserved Vitiligo post-trancripts domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CartiGenea®-AC: An autologous suspension of ex vivo expanded cartilage cells of combined medium for autologous use based on an effective method for the optimization of ACT protocols using iterative reconstruction algorithms compared with patient data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico annotated drug discovery interactive approach for the depletion of tumor-associated macrophages by a computer-aided designed canditate druggable Toll-like receptor (Pam2IDG) peptide-domain targeted by a pharmacophoric mimetic agonistic agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a web server multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Rationally in silico Identification of a immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico rational computer-aided designed of Antimicrobial Peptide-mimetic Psoriasin (S100A7) and Koebnerisin (S100A15) high binding free energy pharmacophoric hyper-scaffolds as a novel synthetic pharmaco-ligand with potential inhibitory activities for the Suppression of the Extracellular Matrix Production and Proliferation of Human Fibroblasts

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico rationally designed of a Peptide-mimic pharmacologic low mass predicted chemorecored poly-druggable-structure for the possible potentiating of the efficient delivery of gene constructs through for the internalization successes in experimental therapy of muscular dystrophies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A surface representation designed IHMVYSK peptide-mimo based chemo-ligand comprising therapeutic vaccine-like agonistic properties as a potential novel druggable synthetic regulator for future allergic and autoimmune treatment applications

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ligand based prediction of a virion-attached pharmacophore cross-reacting synthetic EQHHRRTDN/GAAIGLAWIPYFGPAA peptide mimetic ligand comprising potential therapeutic properties against Ebola virus conserved conserved EBO16 over-expressed regions

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Development of a novel class of VDAC1-peptide mimetic tubulin targeted HA14-1-based multivalent chemical inhibitor with promising anticancer activities as novel pro-apoptotic annotated agent for B-cell chronic lymphocytic leukemia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico development of a unique fragment poly-pharmacologic modulator of CXCR4 tumor-derived heat-shock GGHFGPFDY peptide mimotopic complex-96 (HSPPC-96) by highthroughput identifying hits in the hydrophobic autotaxin/lysophospholipase D pocket

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computer designed of a Safe and immunogenic pharmacophoric activator mimicking physicochemical properties of the MART-1 (26-35,27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) inadjuvantwith PF-3512676 and GM-CSF with promising clinical outcome in metastatic melanoma using a new cluster of algorithms and a Ligand-Based Virtual Screening approach through a Support Vector and Information Fusion Bayesian Machine

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Rational cross-docking interactive structure based integrating approach for the computer assisted generation of pDRS-18-plectasin peptide-mimetic pharmacophore comprising antibiotic properties with therapeutic potential from a saprophytic fungus

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Telomerase Peptide Vaccination simulated poly-chemo mimotopic pharmacological structure Combined with Temozolomide as a novel in silico promising anti-cancer drug-like agent in Stage IV Melanoma Patients generated by the BiogenetoligandorolTM based parallel web service for structural proteome-wide multi-targeted ligand-binding conserved binding pharmacophoric site comparison

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Hyper drug-target interaction analysis for the In silico free energy potency optimization for the in silico discovery of a poly-targeted binding-pocket peptide mimic annotated chemo-antagonists to HIV-II viral replication cycle associated enzymes

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico designed conserved tetrapeptide motif-mimetic pharmacostructure for the potentiating the apoptosis through IAP-binding as a promising neo-agonistic chemo-activator in cancer and the neurodegenerative disorders

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico KIF20A-derived Peptide agonistic mimicking sited and computer-aided designed poly-chemo-scaffold as an innovative drug-like molecule comprising potential clinical hyper-inhibitor properties in Patients With Advanced Pancreatic Cancer when combined with Gemcitabine

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A COMPUTER-assisted Identified Ii-Key/HER-2/ neu(776-790) Hybrid poly-mimic peptide mimotopic vaccine-like chemostructure with active pharmacophore sites as a future in silico promising novel inhibitor trans-activator in Prostate Cancer Patients generated by the BiogenetoligandorolTM and ChemMine tools

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico discovery of novel chemo-hyperstructure as a novel drug discovery dual targeting of the p53 and NF-κB pathways for the activation of the p53 tumor suppressor pathway by an engineered P44 cyclotidomimic agonisitic mechanistic pharmacoligand

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico rational designed adenovirus library displaying random peptide-mimic pharmacophoric ligand supressor of the viral naive tropism comprising replication-competent Oncolytic virus potential therapeutic properties for as a pancreatic cancer

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico development of a unique fragment poly-pharmacologic modulator of CXCR4 tumor-derived heat-shock GGHFGPFDY peptide mimotopic complex-96 (HSPPC-96) by highthroughput identifying hits in the hydrophobic autotaxin/lysophospholipase D pocket

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A conditional probability solution strategy for the in silico identification of the NMDA and metabotropic glutamate receptor subtype 5 targeted by a conantokin GGX1X1SAX1X1LTX5 peptide mimo-formula as an advanced promising antipsychotic potentiator

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An algorithm for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmaco-structures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

GENEA-Sapemitor-45345. An In silico Structure-based designed of an apelin-analogue pharmacophoric agent for the mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischemia-reperfusion injury using a robability fusion approach for scoring multi-parameter drug-likeness during the lead optimization stage of drug discovery.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Algebraically in silico discovered of a multi-epitope mimic poly-pharmacophore to Multiple Peptides Derived from Cancer-Testis Antigens as a promising anti-tumor pharmaco-agent for the maintance of a Specific T-cell Response in Long-term Vaccinated patients Advanced Biliary Tract Cancer using a parallel web service for structural proteome-wide ligand-binding site comparison

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An algorithm for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmaco-structures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico chemoproteomic prediction-scan for the generation of a tyrosinase aa95-104FMGFNCGNCK antigenic patternLFA-3/IgG fusion polypeptide IleAlaArgArgPheLeuOH (Kinetensin) mimetic pharmacophore on conserved Vitiligo post-trancripts domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An In silico designed Wilms’ Tumour 1 (WT1) derived peptide mimetic of high free binding energy pharmacophoric chemo-agonist as a future vaacine like druggable compound with potential clinical benefits in patients with acute myeloid leukaemia by inducing a short-lived WT1-specific immune responses Immunogenicity

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico design of a C-type natriuretic motivo-active conserved peptide mimic conserved pharmacophore as an innovative recored fragment-based possible molecule for the attenuation of lipopolysaccharide-induced acute lung injuries

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computer designed of a Safe and immunogenic pharmacophoric activator mimicking physicochemical properties of the MART-1 (26-35,27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) inadjuvantwith PF-3512676 and GM-CSF with promising clinical outcome in metastatic melanoma using a new cluster of algorithms and a Ligand-Based Virtual Screening approach through a Support Vector and Information Fusion Bayesian Machine

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An In silico predicted and computer-aided molecular designed CTLA-4 blockador for the increasement of the antigen-specific CD8+ T-cells to the inprevaccinated patients with melanoma using the BiogenetoligandorolTM new cluster of algorithms and the istar through a Web Platform for Large-Scale Protein-Ligand Docking experiments

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Lead identification and computer-aided molecular optimization of novel collagenase inhibitors consisting of a recored VAAHE/PRCGNPD peptidomimic highthroughput screened pharmacophore features to matrix contributing of disease arthritis states

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ligand based prediction of a virion-attached pharmacophore cross-reacting synthetic EQHHRRTDN/GAAIGLAWIPYFGPAA peptide mimetic ligand comprising potential therapeutic properties against Ebola virus conserved conserved EBO16 over-expressed regions

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico discovery of novel chemo-hyperstructure as a novel drug discovery dual targeting of the p53 and NF-κB pathways for the activation of the p53 tumor suppressor pathway by an engineered P44 cyclotidomimic agonisitic mechanistic pharmacoligand

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Rational design of ApoA-I Mimetic-polypharmacophoric of high free binding energy hopping scaffolds generated by integrating nonlinear scoring functions for similarity-based ligand docking and binding affinity prediction

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An In silico predicted and computer-aided molecular designed CTLA-4 blockador for the increasement of the antigen-specific CD8+ T-cells to the inprevaccinated patients with melanoma using the BiogenetoligandorolTM new cluster of algorithms and the istar through a Web Platform for Large-Scale Protein-Ligand Docking experiments

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

ArthroGenea®-AR is a Mesenchymal stem cells enriched Chondrocytes of ex vivo derived Chondrogenic Autologous Treatment for patients with Cartilage defects and Osteoarthritis

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A shannon entropy descriptor (SHED) for the in silico prediction of an annotated suitable lead chemo-recored compound as a potent computer predicted inhibitor comprising potential hyper-mimicking activities to 5 conserved anti-plasmodium peptides

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computer-aided synthesis and characterization of a novel motif like PSA-PSM-PAP-Huk2-hK2 peptide mimetic poly-chemical recored prostate cancer-targeted PI3 kinase hyper-inhibitor as a promising in silico designed anti-tumor vaccine-like molecule

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico discovery of a Asn-Ile-Ile-Gly-Val-Ser-Tyr peptide mimetic high free energy recored chemical analog molecule CFTR targeted binding sites as a future mutant corrector against over-expressed cystic fibrosis pathological post-transcripts

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In Silico generation of a sophisticated descriptor for the in silico identification and free energy evaluation of hybrid KPQRKTKRNT peptidomimetic leads for a potential, simultaneous inhibition of helicase and HCV´sStructural NS3/4A protease regions

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A mechanistic in silico molecular recognized approach for the ligand based generation of a dual N-formyl-Met-Leu-Phe (fMLP), and MMK-1peptide mimetic hyper-agonist fMLP targeted receptor against the PGE2 EP4 pathway chemotherapy-induced alopecia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico discovery and rationally prediction of the solution structure of differential peptide mimetic active inhibitors of LINE1 and LINE2 conserved retrotransposition mechanism in the host defence AID/APOBEC protein motif derived binding domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A ligand pocket binding in silico discovery of small-molecule PUMA targeted ACPP (ACPP-RGD) peptide mimotopic hyper-Inhibitory agent as a potent pharmacoregulator comprising potential activities for the mitigation of the radiation-Induced cell death

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A predicted chemo-polypharmacophoric agent comprising (Propeptide-Fc)/MGF peptide mimicking interactive of high free binding energy properties towards Wnt7a/Fzd7 signalling Akt/mTOR anabolic growth IGF-I/PI3K/Akt -I/MAPK/ERK pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CartireGENEATM®-CP: A Mesenchymal stem cells enriched chondrocytes as a combinatorial Autologous Treatment for patients with cartilage defects. A choice of statistical methods for comparisons of dosimetric data in cartilopoietic therapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Material properties of bovine intervertebral discs across strain rates – dataset

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CartiGenea®-AC: A Mesenchymal stem cells enriched Autologous Chondrocytes for the Treatment of patients with cartilaginous defects on a New Drug-Cell Combinatory Effect Prediction Algorithm on the Cell Based on Chondro defects Gene Expression and Dose-Response Curve.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

The Possibility of Multivisceral Resection for Advanced Gastric Cancer – Case Report

Maksim A Evseev, Yulia L Podberezina and Aleksey L Vladykin

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017264

Forgotten Volkmann Operation (Modified Radical Mastectomy) and its Value in Modern Combined Treatment of Breast Cancer

Valerijus Ostapenko, Andrej Ostapenko and Edvin Ostapenko

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017263

Lymphoma Involving the Heart and Inferior Vena Cava: Radiological and Pathological Approach

Duminda WD, Pathirana KG, Lekamge IN, Weerakoon S, De Silva YAP, Ganewatte E, Appuhamy WNDPC, Parthipan N, Senadeera RL, Jayawickrama M and Gayani GHP

Case Report – Cancer Stud Ther J

DOI: 10.31038/CST.2017262

Discovery of Resistance Pathways to Fibroblast Growth Factor Receptor Inhibition in Bladder Cancer

Sumanta K Pal, Miaoling He, Jeremy O Jones

Research Article – Cancer Stud Ther J

DOI: 10.31038/CST.2017261

Proposal on Cooperation on 100 Novel Drug Formulas

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Drug Formulas – Cancer Stud Ther J

Evaluation of an Inverse Molecular Design Algorithm in a Model Binding Site as An In silico predicted and computer-aided molecular designed HIV-1 protease CTLA-4 blockador for the increasement of the antigen-specific W191G mutant of cytochrome c peroxidase CD8+ T-cells to the inprevaccinated patients with melanoma using new cluster of algorithms for Large-Scale Protein-Ligand Docking experiments

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum mechanically derived AMBER-compatible Algebraically in silico discovery of a multi-epitope mimic poly-pharmacophore to Multiple Peptides Derived from Cancer-Testis Antigens as a promising anti-tumor pharmaco-agent for the maintance of a Specific T-cell Response in Long-term Vaccinated patients Advanced Biliary Tract Cancer using a parallel Cloud computing for protein-ligand binding site comparison for structural proteome-wide ligand-binding site comparisons

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Evaluation of an Inverse Molecular Design Algorithm in a Model Binding Site in silico designed dosimetric autologous living vaccine consisting of with Multiple Wilms’ Tumor 1 WT1-ConSynthetic–Restricted Peptide mimotopic Epitopes RMFPNAPYLP pulsed dendritic cells on a personalized Active Network analysis for asymptomatic or minimally symptomatic metastatic Pancreatic Cancer

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Experimental superposition of orders of quantum gatesAn in silico designed dosimetric autologous living vaccine consisting of with Multiple Wilms’ Tumor 1 WT1-ConSynthetic–Restricted Peptide mimotopic Epitopes RMFPNAPYLP pulsed dendritic cells on a personalized Active Network analysis for asymptomatic or minimally symptomatic metastatic Pancreatic Cancer

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Experimental simulation of Novel procedure quantum tunneling in small Computational Scaffolding systems on tumorigenic stem cell bacterial infected hybrids for the in silico rescaffolding and side-chain optimization on the neutrophil immune defense CAP37 protein

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Demonstration of quantum permutation algorithm with a single photon ququart on Combinatorial learning procedures and graph transformations for the discovery of tumor-like cardiomyocyte derived eletroporated combined hybrids on a Meta-Dynamic Meta-node stemness reconstructing approach for the in silico generation of a anti-(JAM-A) drug-construct

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Fast stochastic optimization of a quantum permutation algorithm with a single photon ququart algorithm on DC-tumor like high yield minimal magnetic signatures of electrotransfectioned ex vivo mediated hybrids for the generation of a computer-aided designed candidate drugable Toll-like receptor (Pam2IDG) peptide-domain agonistic agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Merging and scoring molecular interactions utilising existing community standards: tools, use-cases and a case study of QM/MM in rational drug discovery and molecular diversity for the construction of an anti-alpha-bungarotoxin binding MAP-p6.7 peptide mimetic ligand against nicotinic receptor binding site as a potent snake neurotoxin synthetic antidote.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Circular Scale of Time as a Way of Calculating the Quantum-Mechanical Perturbation Energy Given by the Schrödinger Method in QM/MM rational drug discovery and molecular diversity for the construction of an anti-alpha-bungarotoxin binding MAP-p6.7 peptide mimetic ligand against nicotinic receptor binding site as a potent snake neurotoxin synthetic antidote.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Can Von Neumann’s Theory Meet Quantum Aggregation Computation simulated studies on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators of α-Synuclein aggregation as a emerging template for drug discovery in α-synucleinopathy interfering amyloidogenesis pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Estimation of Solvation Entropy and Enthalpy via Analysis of Water Oxygen–Hydrogen CorrelationsAn algorithm for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ensemble quantum computing by NMR spectroscopy An algorithm for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Quantum algorithm for collapsing the perfect superposition to a chosen quantum state without applying any in silico designed measurements of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a web server multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Molecular dynamics simulations: from structure function relationships to αn advanced fragment-based multi-dimensional chemico-informatic drug discovery approach on a ex vivo derivation and expansion of human neuropoietic cell progenitors using highly conserved poly-peptidomimic linked-pharmacophores targeted to neural pathways for neurodegenerative disease modeling

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Reformulation of Relativistic Quantum Field Theory Using an advanced fragment-based multi-dimensional chemico-informatic Region-Like Idealization approach of the Ex vivo derivation and expansion of Elementary Particle human neuropoietic cell progenitors on highly conserved poly-peptidomimic linked-pharmacophores targeted to neural pathways for neurodegenerative disease modeling

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Molecular dynamics simulations: from structure function relationships to an In silico discovery of a novel multi-chemo-structure super-agonistic CellshOX Decoy Peptide Mimetic Construct as a Human Umbilical Cord blood Stem Cell Expansion Molecule in a QSAR automating modeling lead compound design approach

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A New Way to Implement Quantum Computation In silico Lindenbaum-Tarski algebra as a 3D logical space discovery of a novel multi-chemo-structure super-agonistic CellshOX Decoy Peptide Mimetic Human Umbilical Cord blood Stem Cell Expansion Molecule Construct in a QSAR automating modeling lead compound design approach

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Three-Party Simultaneous Quantum Secure Communication Based on Closed Transmission in silico discovery of a novel multi-chemo-structure super-agonistic CellshOX Decoy Peptide Mimetic Construct as a Human Umbilical Cord blood Stem Cell Expansion Molecule in a QSAR automating modeling lead compound design approach

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Computational mining Biomolecular simulation modelling combined molecular docking-based and pharmacophore-based target prediction strategy through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computational mining combined molecular docking-based and pharmacophore-based approach as a target prediction strategy through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Von Neumann’s Theory Projective Measurement Quantum Computational mining combined molecular docking and pharmacophore-based approach on Molecular Dynamics Simulations of the DNA-CNT Interaction Process to Hybrid Quantum Chemistry Potential and Classical Trajectory prediction strategies through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computational modelling of biomolecular simulation methods in structural biology interfaces between physics, chemistry and biology on an atomistic scalable literature computer-based discovery of an annotated SPR4-peptide-similar multi-molecular pharmacophoric reverse docked super-agonist scaffold as a canditate bone metabolism regulator

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Assessment of comparison of dynamic and static algorithmic models for predicting drug–drug interactions via inhibition mechanisms for a scalable literature Computer-based discovery of an annotated SPR4-peptide-similar multi-molecular reverse docked super-agonist pharmacophoric scaffold as a canditate bone metabolism regulator

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ligand-Binding Affinity Estimates Supported by Quantum-Mechanical Methods on an atomistic scalable literature computer-based discovery of an annotated SPR4-peptide-similar multi-molecular pharmacophoric reverse docked super-agonist scaffold as a canditate bone metabolism regulator

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A rational in silico drug-target flexibility complement “Smart Design” methodology of Quantum Wells and Double-Quantum Wells Structures for the generation of a peptide-mimic novel pharmacoelement binding to the amino acid conserved sequences of the active loop of a Haemophilus influenzae porin P2

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum-Inspired Neural Networks with Application in silico drug-target flexibility complement methodology-design for the generation of a peptide-mimic novel pharmacoelement binding to the amino acid conserved sequences of the active loop of a Haemophilus influenzae porin P2

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico rational Biomolecular simulation and modelling: status, progress and prospects identifications of a immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computer-Aided Drug Design: An Innovative Tool for in silico Modeling Identification of a immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies. Rationally in silico Identification of a immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

NNScore: A Neural-Network-Based Scoring Function for the Characterization of Protein−Ligand Complexes Computer-Aided Drug Design as an Innovative Tool for the in silico Identification of a immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Conformational Dynamics Quantum Key Distribution with Qubit Pairs and Binding Free Energies From the Perspective of Protonation Equilibria as an in silico annotated drug discovery interactive approach of Inhibitors of BACE-1 of tumor-associated macrophages by a computer-aided designed canditate druggable Toll-like receptor (Pam2IDG) peptide-domain targeted by a pharmacophoric mimetic agonistic agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Improved Quantum-Behaved Particle Swarm Optimization Algorithm with Elitist Breeding for Unconstrained Optimization Statistical Mechanics for Weak Measurements and Quantum Inseparability Novel procedure Computational Scaffolding on tumorigenic stem cell bacterial infected hybrids for the in silico rescaffolding and side-chain optimization on the neutrophil immune defense CAP37 protein

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties for Unconstrained Optimization Statistical Mechanics for Weak Measurements and Quantum Inseparability Novel procedure Computational Scaffolding on tumorigenic stem cell bacterial infected hybrids for the in silico rescaffolding and side-chain optimization on the neutrophil immune defense CAP37 protein

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

New HADDOCK Scoring Function for Protein-Peptide Docking on a SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Adaptive quantum computation in changing environments using a multi-mimotopic algorithmic approach for biclustering analysis of expression data projective simulation on an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Circular Scale of Time and Energy of a Quantum State Calculated from the Schrödinger Perturbation Theory on computational target fishing mining machinery based chemogenomic databases as an Identification tool for predicting therapeutic potential of a high-potency GLP-1, INGAP-P/IGLHDPSHGTLPNGS peptide mimetic insulinotropic compounds

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A computational target fishing mining machinery Process Model of Quantum Mechanics Circular Scale of Time and Energy of a Quantum State Calculated from the Schrödinger Perturbation Theory as an Identification tool for predicting therapeutic potential of GLP-1, INGAP-P/IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A novel drug-target combined Bayesian formulation for the Rational Discovery of a Specific FWCS/LQIHFTLIXAFCCEN Peptide mimetic Pharmacophoric Inhibitor against p38a MAPK at HNSCC Allosteric-Sites on Hypercomplex based Extensions of Quantum Theory

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Exact Mathematical Picture of Quantum SpacetimeOn Hypercomplex Extensions of Quantum TheoryA novel drug-target combined Bayesian formulation for the Rational Discovery of a Specific FWCS/LQIHFTLIXAFCCEN Peptide mimetic Pharmacophoric Inhibitor against p38a MAPK at HNSCC Allosteric-Sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Identification of one-bead by one-compound computer-aided discovery of a novel peptide mimetic pharmacophore against human ovarian cancer highly expressed from conserved mRNAs-cDGX4GX6X7c associated combinatorial libraries

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Reformulation of Relativistic Quantum Field Theory Using Region-Like Idealization of the Elementary Particle Identification of an one-bead by one-compound computer-aided discovery novel peptide mimetic pharmacophore against human ovarian cancer highly expressed on conserved mRNAs-cDGX4GX6X7c associated combinatorial libraries

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Conformational Dynamics and Binding Free Energies of Inhibitors of BACE-1: From the Perspective of Protonation Equilibria to the in silico design of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Sensing of molecules using quantum dynamics Discovery and a computerized quantitative bio-informatic in silico Development of a Synthetic Gp 46-gp21 derived P400-P197 Peptide mimetic pharmacophore as a potential HTLV-1 Fusion Inhibitor in a mass-action law based new cluster of algorithms

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Analysis of Security of Quantum Key Distribution Based on Entangled Photon Pairs by in silico Model Checking Development of a Synthetic Gp 46-gp21 derived P400-P197 Peptide mimetic pharmacophore as a potential HTLV-1 Fusion Inhibitor in a mass-action law based new cluster of algorithms

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Conformational Dynamics and Binding Free Energies of Inhibitors of BACE-1: From the Perspective of Protonation Equilibria Discovery and a computerized quantitative bio-informatic in silico Development of a Synthetic Gp 46-gp21 derived P400-P197 Peptide mimetic pharmacophore as a potential HTLV-1 Fusion Inhibitor in a mass-action law based new cluster of algorithmsSensing of molecules using quantum dynamics

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Virtual Numbers to Represent Entangled Quantum parallel adaptive finite element simplified spherical harmonics States approximation solver for frequency domain fluorescence molecular imaging to identify several global patterns for anti-HIV-1 cell cycle viral replication enzymes for the efficient discovery of homomultimerized HIV short linear motif-like peptide mimicking lead compound on its functional binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Quantum-Inspired Particle Swarm Optimization Algorithm Encoded by Probability Amplitudes of Multi-Qubit cursory analysis to identify several global patterns for anti-HIV-1 cell cycle viral replication enzymes for the efficient discovery of homomultimerized HIV short linear motif-like peptide mimicking lead compound on its functional binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Virtual Numbers to Represent Entangled Quantum States cursory analysis to identify several global patterns for anti-HIV-1 cell cycle viral replication enzymes for the efficient discovery of homomultimerized HIV short linear motif-like peptide mimicking lead compound on its functional binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Study of Quantum Strategies for Newcomb’s Paradox cursory analysis to identify several global patterns for anti-HIV-1 cell cycle viral replication enzymes for the efficient discovery of homomultimerized HIV short linear motif-like peptide mimicking lead compound on its functional binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Sensing of Quantum Discord of a Two-Qubit Anisotropy XXZ Heisenberg Chain with Dzyaloshinskii-Moriya Interaction molecules quantum dynamics cursory analysis to identify several global patterns for anti-HIV-1 cell cycle viral replication enzymes for the efficient discovery of homomultimerized HIV short linear motif-like peptide mimicking lead compound on its functional binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A haplotype phasing algorithm-based Study of Quantum Strategies for Newcomb’s Paradox. rational methodology for the pharmacological discovery of an advanced Peptide-mimetic Poly-Chemo-construct pharmacophore as a potential canditate compound for Previously Treated Advanced Colorectal Cancer patients

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Undulatory Theory with Paraconsistent Logic (Part I): Quantum Logical Model with Two Wave haplotype phasing algorithm-based rational methodology for the pharmacological discovery of an advanced Peptide-mimetic Poly-Chemo-construct pharmacophore as a potential canditate compound for Previously Treated Advanced Colorectal Cancer patients

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Entanglement Criterion for States in Infinite Dimensional Bipartite Quantum Highthroughput docking validations Systems using fractions of intermolecular interactions for the in silico generation of a synthetic IL-23 derivbed (teeeqqly)-mimetic multichemical noncompetitive antagonist with possible anti-inflammatory responses

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Highthroughput docking validations using No Quantum Process of the Preferred Basis: Decoherence in Universal fractions of intermolecular interactions for the in silico generation of a synthetic IL-23 derivbed (teeeqqly)-mimetic multichemical noncompetitive antagonist with possible anti-inflammatory responses

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A New Way to Implement large scale Quantum Computation chemical data mining drug discovery relative exploration for a descriptor-based encoding of selected hits atom types to a multi-covalent fragment-based pharmaco-ligand against novel elucidated active β-amyloid Peptide binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Emerging Computational Methods for the Rational large scale chemical data mining allosteric drug discovery of relative exploration for a descriptor-based encoding of selected hits atom types to a multi-covalent fragment-based pharmaco-ligand against novel elucidated active β-amyloid Peptide binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Teleportation with an Accelerated of a large scale chemical data mining drug discovery relative exploration for a descriptor-based encoding of selected hits atom types to a multi-covalent fragment-based pharmaco-ligand against novel elucidated active β-amyloid Peptide binding sites

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Entanglement Dark Energy and Negative Gravity plus Circular Scale of quantitative structure-activity relationship time as a Way of Calculating the Quantum-Mechanical Perturbation Energy Given by the Schrödinger Method with novel Stanisław Olszewski Accelerated Expansion Universe automated lazy learning modelings for the generation of pharmacophore-based custom fingerprinting of high quality atom encoding Endosomolytic Peptide-mimetic agent as siRNA carrier

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Survey of Quantum Lyapunov Control maximum common substructure-based support vector machine algorithmic methods for the Fragment based drug discovery of drug like optimized Alpha-Helical Cationic Anticancer Peptide-mimetic annotated Pharmacophore

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Survey of Quantum Lyapunov Control maximum common substructure-based support vector machine algorithm for the Fragment based drug discovery of drug like optimized Alpha-Helical Cationic Anticancer Peptide-mimetic annotated Pharmacophore

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum algorithms for topological and geometric analysis of computational methods and a metastasis perfomed thermodynamic integration approach for the discovery of a potent aromatase/collagen IV derived biomimetic dual targeted small poly-active compound with future anti-tumor inhibitory activities

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Tailoring Quantum Correlations of a Coupled Central Two Qubits Soaked in a Finite Temperature Antiferromagnetic Environment with Frequency Gap the discovery of a potent aromatase/collagen IV derived biomimetic dual targeted small poly-active compound with future anti-tumor inhibitory activities

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Biology on the Edge of Quantum Chaos Computational mining approach, a combined molecular docking-based and pharmacophore-based target prediction strategy through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Hybrid Quantum Chemistry Molecular Dynamics Simulations of the Classical Trajectory DNA-CNT combined molecular docking-based and pharmacophore-based target prediction strategy through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

On a Non-Perturbative Quantum Relativity Theory Leading to a Casimir-Dark Energy Nanotech Reactor Proposal on a combined molecular docking-based and pharmacophore-based target prediction strategy through a probabilistic fusion method for target ranking of anti-HIV-I P24-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Linguistic Interpretation of Quantum Mechanics in a combined molecular docking-based and pharmacophore-based target prediction Projection Postulate Approach strategy-derived peptide mimic promising pharmacophores

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum dynamics in Variational solvent-solute interface continuum High-dimension profiling data for proton transport II multifunctional peptide-mimic chemo-structure generation by connecting conserved fragments based on the neutrophil immune defense CAP37 protein as an in-silico antibacterial and wound-healing canditate agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Von Neumann’s Theory, Projective Measurement, and Quantum Computation data generations of a multifunctional peptide-mimic chemo-structure by connecting conserved fragments based on the neutrophil immune defense CAP37 protein as an in-silico antibacterial and wound-healing canditate agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A computer aided generation of a prototype superset Stapled HIV-1 peptide-similar full-match pharmacophoric poly-agent recapitulating antigenic viral replication structures bounded broadly targeted to the neutralizing 4E10 and 10E8 antibodies.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A variational eigenvalue solver rational design of a computer-aided poly-pharmacophore on a photonic quantum processor synthetic molecule comprising therapeutic peptide-mimic superagonistic properties of 829,16kcal.mol against to Ebola virus conserved protein regions

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Rational Elaborated Common Strategies employed MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities for the efficient in silico optimization of an accesible synthetically (AMPs) peptidomimetic-similar to an amphiphile-based pharmacophoric agent as a promising enhanced therapeutic antimicrobial agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

De novo ligand Identification Complementary Approaches to Existing Target Based Drug Discovery for Identifying Novel Drug Targets of a structural ligand-based synthetically accesible pharmacophoric determinant on tau protein-mimic conserved motif peptide chemical elements as an annotated promising therapy in Alzheimer’s disease

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Meta-Dynamic Meta-node Hybrid Quantum Chemistry Potential and Classical Trajectory Molecular Dynamics Simulations of the DNA-CNT Interaction reconsrtructing approach for the in silico generation of a drug-construct consisting of annotated Anti-inflammatory anti-(JAM-A) peptide-mimic pharmacophores with a potential myocardial infarction therapeutic activity

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Discord of an in silico Interaction designed Two-Qubit Anisotropy XXZ Heisenberg Chain with Dzyaloshinskii-Moriya Fusion Inhibitor consisting of five cancer filtered conserved pharmacophoric chemical fragments with Greatly Promising Pharmaco-Mimic Properties to a Rationally Engineered Wilms’ Tumor Peptide as a future computer generated hyper-molecule for the potential treatment of the acute myeloid leukemia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Discord of a Two-Qubit Anisotropy XXZ Heisenberg Chain with a Dzyaloshinskii-Moriya predicted Interaction analysis for the discovery of a chemo-polypharmacophoric agent comprising (Propeptide-Fc)/MGF peptide mimicking interactive of high free binding energy properties towards Wnt7a/Fzd7 signalling Akt/mTOR anabolic growth IGF-I/PI3K/Akt -I/MAPK/ERK pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A maximum common substructure-based Quantum Navigation and Ranking in Complex Networks support vector machine algorithm for the Fragment based drug discovery of optimized Alpha-Helical Cationic Anticancer Peptide-mimetic annotated Pharmacophore

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Improved data computer Quantum Algorithm for Chemically Tractable, Semi-Automated topological and geometric Protein Inhibitor Design analysis simulated of a gp100 Peptide mimic pharmacophore as a Vaccine-like and Interleukin-2 in silico generated superagonist with potential clinical effect in Patients with Advanced Melanoma

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Improved Mathematical data computer simulated Modeling for Quantum Electron Wave Mechanichs Algorithm for Chemically Tractable, Semi-Automated Protein Inhibitor Design of a gp100 Peptide mimic designed pharmacophore as a Vaccine-like and Interleukin-2 in silico generated superagonist with potential clinical effect in Patients with Advanced Melanoma

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Unified Platform for AI and Big Data Analytics Logical computations using algorithmic self-assembly RGD-FHRRIKA-RARADADA-IKVAV responsive peptide-modified mimetic triple-crossover hydrothermochemic molecules for tissue regeneration

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Unified Platform for AI and Big Data semi-empirical D&C Analytics strategy as an improvement of the linear interaction energy model with electrostatic salvation for the generation TP4 (AMP) antimicrobial peptide mimetic pharmacoligand, against H.Pylori infection within accurate enthalpy values

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Modeling for Collapsing Cavitation Bubble near Rough Solid Wall by Mulit-Relaxation-Time Pseudopotential Lattice Boltzmann Model target-ligand based approaches using predicted binding affinity matrices as a Chemogenomics-Driven NCR, Lfpep, Brevinin-1Sa and kaliocin-1 peptidomimetic Drug Discovery Neo-agent against Candida albicans antimicrobial CXG motif signatures

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ultimate target-ligand based Quantum learning Drug Discovery without quantum memory approaches using predicted binding affinity matrices as a Chemogenomics-Driven NCR, Lfpep, Brevinin-1Sa and kaliocin-1 peptidomimetic Neo-agent against Candida albicans antimicrobial CXG motif signatures

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Mechanics and the Philosophy of drug discovery Language: Reconsideration of Traditional Aggregation simulated studies on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators of α-Synuclein aggregation as a emerging template for drug discovery in α-synucleinopathy interfering amyloidogenesis pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Challenging the importance of Oscillation and Asymptotic Behaviour of aromatic Solutions of Nonlinear Two-Dimensional Neutral Delay Difference Systems in amyloidosis aromatic interactions via aliphatic LD6(LAGD), ID3(IVD) and KE7(KLVFFAE) peptides, as a novel GA-biophoric scaffold for the generation of similar self-assembly chemico-lead molecules to amyloid core sequences

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization by Mapping of Topological Quantum Circuits to a Physical Hardware multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization by Mapping of Topological Quantum Circuits to a Physical Hardware multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed multi-mimotopic algorithmic approach for biclustering analysis of an Anticancer Peptide SVS-1 multipharmacophore expression data as a potential drug-like efficator in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design rational approach for the in silico generation of a TCR Peptide Mimetic Pharmacoligand as a potential chemo-modulator in Human Autoimmune Diseases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Walk of Two Quantum Particles on One computer-aided drug design rational Dimensional System for the in silico generation of a TCR Peptide Mimetic Pharmacoligand as a potential chemo-modulator in Human Autoimmune Diseases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Computer rational Statistical Mechanics for Weak Measurements and Quantum computer-aided drug design Inseparabilities for the in silico generation of a TCR Peptide Mimetic Pharmacoligand as a potential chemo-modulator in Human Autoimmune Diseases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Approximate Quantum State Sharings via Pair of Private Quantum In silico designed Channels of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an biclustering analysis of expression data Develop and Test a Solvent Accessible Surface Area-Based Model in Conformational Entropy Calculations by a multi-mimotopic algorithmic approach for Anticancer Peptide SVS-1 multipharmacophore predictions as a potential drug-like efficator in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Multiscale geometric modeling of macromolecules I: Cartesian representation Quantum-SAR Extension of the Spectral-SAR Algorithm Application to Polyphenolic Anticancer Bioactivity through a decision-tree induction algorithm-based Drug Discovery, homology modeling, hierarchical docking and virtual screening approaches of Antimicrobial Peptide-mimetic Psoriasin (S100A7) and Koebnerisin (S100A15) high binding free energy pharmacophoric hyper-scaffolds as a novel synthetic pharmaco-ligand with potential inhibitory activities for the Suppression of the Extracellular Matrix Production and Proliferation of Human Fibroblasts

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Proposed Strategy in Teaching Design Fundamentals for Understanding the Relationship between Idea and Idea’s Projection of an in silico rational computer-aided designed Antimicrobial Peptide-mimetic Psoriasin (S100A7) and Koebnerisin (S100A15) high binding free energy pharmacophoric hyper-scaffolds as a novel synthetic pharmaco-ligand with potential inhibitory activities for the Suppression of the Extracellular Matrix Production and Proliferation of Human Fibroblasts

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A New Interpretation of an in silico rational computer-aided designed Quantum Mechanics of Antimicrobial Peptide-mimetic Psoriasin (S100A7) and Koebnerisin (S100A15) high binding free energy pharmacophoric hyper-scaffolds as a novel synthetic pharmaco-ligand with potential inhibitory activities for the Suppression of the Extracellular Matrix Production and Proliferation of Human Fibroblasts

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A predicted chemo-polypharmacophoric agent on Hypercomplex Extensions of a Quantum Theory Bayesian parameter estimation for nonlinear modelling of biological pathways comprising (Propeptide-Fc)/MGF peptide mimicking high free binding energy properties towards Wnt7a/Fzd7 signalling Akt/mTOR anabolic growth IGF-I/PI3K/Akt -I/MAPK/ERK pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A predicted chemo-polypharmacophoric agent Bayesian parameter estimation for nonlinear modelling of biological pathways comprising (Propeptide-Fc)/MGF peptide mimicking of high free binding energy properties towards Wnt7a/Fzd7 signalling Akt/mTOR anabolic growth IGF-I/PI3K/Akt -I/MAPK/ERK pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Computational Parameter Estimation of Fractional-Order Chaotic Systems by Using Quantum Parallel Particle Swarm Optimization Algorithm Assay to Design an Epitope-Based Mimo-Peptidic hyper agonist consisting of linked active Pharmacophoric chemo-Scaffolds comprising in silico demonstrated vaccine-like potential properties against Saint Louis Encephalitis Virus conserved binding domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico Quantum Discord of a Two-Qubit Anisotropy XXZ Heisenberg Chain with Dzyaloshinskii-Moriya Interactions on a designed Fusion Inhibitor consisting of five cancer filtered conserved pharmacophoric chemical fragments with Greatly Promising Pharmaco-Mimic Properties to a Rationally Engineered Wilms’ Tumor Peptide as a future computer generated hyper-molecule for the potential treatment of the acute myeloid leukemia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A mechanistic in silico molecular recognized approach for the ligand based generation of a dual N-formyl-Met-Leu-Phe (fMLP), and MMK-1peptide mimetic hyper-agonist fMLP targeted receptor against the PGE2 EP4 pathway chemotherapy-induced alopecia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Complementary Approaches to Existing Target Based Drug Discovery for Identifying Novel Drug Targets A mechanistic in silico molecular recognized approach for the ligand based generation of a dual N-formyl-Met-Leu-Phe (fMLP), and MMK-1peptide mimetic hyper-agonist fMLP targeted receptor against the PGE2 EP4 pathway chemotherapy-induced alopecia.

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A computer simulated Survey of Quantum Lyapunov Control Methods of a gp100 Peptide pharmacophore mimic Vaccine-like and Interleukin-2 targeted as a in silico generated superagonist with potential clinical effect in Patients with Advanced Melanoma using an Improved Algorithm for Chemically Tractable, Semi-Automated Protein Inhibitor Design

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A CHARMM additive and polarizable force fields for biophysics and computer-aided Cutting Edge Combinatorial Designed Agonistic Stem Cell Inducer Based on a FGF2-Overexpressed Transcriptomic Effect with a Regeneration Competence in Cord Blood Tetanus Toxoid TLR-Free Signaling Associated Simulated Mechanistic Stem Cell Culture System

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum dynamics in continuum for Variational solvent-solute interface proton transport II as a semi-empirical D&C linear interaction energy electrostatic salvation strategy for the generation TP4 (AMP) antimicrobial peptide mimetic pharmacoligand, against H.Pylori infection within accurate enthalpy values

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Complementary Approaches to Existing Target Based Drug Discovery for Identifying Novel Drug Targets A mechanistic in silico molecular recognized approach for the ligand based generation of a dual N-formyl-Met-Leu-Phe (fMLP), and MMK-1peptide mimetic hyper-agonist fMLP targeted receptor against the PGE2 EP4 pathway chemotherapy-induced alopecia

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design Logical computations using algorithmic self-assembly of RGD-FHRRIKA-RARADADA-IKVAV responsive peptide-modified mimetic triple-crossover hydrothermochemic molecules for tissue regeneration

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum dynamics in continuum for proton transport II Variational solvent-solute interface computer-aided drug design Logical computations using algorithmic self-assembly of RGD-FHRRIKA-RARADADA-IKVAV responsive peptide-modified mimetic triple-crossover hydrothermochemic molecules for tissue regeneration

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

The role of QM/MM in rational drug discovery and molecular diversity for the construction of a Circular Scale of Time as a Way of Calculating the Quantum-Mechanical Perturbation Energy Given by the Schrödinger Method towards an anti-alpha-bungarotoxin binding MAP-p6.7 peptide mimetic ligand against nicotinic receptor binding site as a potent snake neurotoxin synthetic antidote

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

The role of a QM/MM variational eigenvalue solver on a photonic quantum processor in rational drug discovery and molecular diversity for the construction of an anti-alpha-bungarotoxin binding MAP-p6.7 peptide mimetic ligand against nicotinic receptor binding site as a potent snake neurotoxin synthetic antidote

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Modeling for a Chemogenomics-Driven NCR, Lfpep, Brevinin-1Sa and kaliocin-1 peptidomimetic Drug Discovery Neo-agent Collapsing Cavitation Bubble near Rough Solid Wall by Mulit-Relaxation-Time Pseudopotential Lattice Boltzmann Model against Candida albicans antimicrobial CXG motif signatures

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design as a Chemogenomics-Driven NCR, Lfpep, Brevinin-1Sa and kaliocin-1 peptidomimetic Drug Discovery Neo-agent against Candida albicans antimicrobial CXG motif signatures

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ultimate target-ligand based approaches using predicted binding affinity matrices as a Chemogenomics-Driven NCR, Lfpep, Brevinin-1Sa and kaliocin-1 peptidomimetic Drug Discovery Neo-agent against Candida albicans antimicrobial CXG motif signatures

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An efficient emerging template for drug discovery algorithm for multipole energies and derivatives based on spherical harmonics and extensions to particle α-Synuclein aggregation simulated mesh Ewalds on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators in α-synucleinopathy interfering amyloidogenesis pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Experimental simulation of quantum tunneling in small α-Synuclein aggregation simulated systems on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators in α-synucleinopathy interfering amyloidogenesis pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Can Von Neumann’s Theory Meet al-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators in α-synucleinopathy interfering amyloidogenesis Quantum Computated pathways?

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Modeling for Collapsing al-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators in α-synucleinopathy interfering amyloidogenesis Cavitations Bubble near Rough Solid Wall by Mulit-Relaxation-Time Pseudopotential Lattice Boltzmann Quantum Computated α-Synuclein aggregation simulated Model

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An efficient algorithm for multipole energies and derivatives based on spherical harmonics and extensions to Aggregation simulated studies on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators of α-Synuclein aggregation as a emerging template for drug discovery in α-synucleinopathy interfering amyloidogenesis particle mesh Ewald pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An efficient algorithm for multipole energies and derivatives based on spherical harmonics and extensions to Aggregation simulated studies on Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators of α-Synuclein aggregation as a emerging template for drug discovery in α-synucleinopathy interfering amyloidogenesis particle mesh Ewald pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Ewald Aggregation simulated studies on an efficient algorithm for multipole energies and derivatives based on spherical harmonics and extensions to particle mesh Amyloid β-sheet helix-rich Val-Gly-Gly-Ala-Thr-Thr-Thr-Gly-Val-Thr peptide mimic modulators of α-Synuclein aggregation as a emerging template for drug discovery in α-synucleinopathy interfering amyloidogenesis pathways

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Challenging the importance of aromatic interactions in amyloidosis via aliphatic LD6(LAGD), ID3(IVD) and KE7(KLVFFAE) peptides, as a novel Experimental simulation of quantum tunneling in small GA-biophoric scaffolds for the generation of similar self-assembly chemico-lead molecules to amyloid core sequences

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An efficient algorithm for multipole energies and derivatives based on spherical harmonics and extensions to particle mesh Ewald of aromatic interactions in amyloidosis via aliphatic LD6(LAGD), ID3(IVD) and KE7(KLVFFAE) peptides, as a novel Experimental simulation of quantum tunneling in small GA-biophoric scaffolds for the generation of similar self-assembly chemico-lead molecules to amyloid core sequences

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Oscillation and Asymptotic Behaviour of Solutions of Nonlinear Two-Dimensional Neutral Delay Difference Systems of aromatic interactions in amyloidosis via aliphatic LD6(LAGD), ID3(IVD) and KE7(KLVFFAE) peptides, as a novel Experimental simulation of quantum tunneling in small GA-biophoric scaffolds for the generation of similar self-assembly chemico-lead molecules to amyloid core sequences

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization by CHARMM additive and polarizable force fields for biophysics and computer-aided drug design multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Experimental simulation of quantum tunneling in small systems of an in silico designed anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization by CHARMM additive and polarizable force fields for biophysics and computer-aided drug design multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Recent multi-target machine learning predictors assessing Intra-Metastasis MicroRNA-155 trainig data sets on MUC1- LLDILDTAGHEEYSAMRDQ targeted domains by a telomerase GV1001 peptide mimetic chemo-pharmacophores for the future induction of CTL responses

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Study of Quantum Strategies for Newcomb’s Paradox Intra-Metastasis MicroRNA-155 trainig data sets on MUC1- LLDILDTAGHEEYSAMRDQ targeted domains by a telomerase GV1001 peptide mimetic chemo-pharmacophores for the future induction of CTL responses

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design Intra-Metastasis MicroRNA-155 trainig data sets on MUC1- LLDILDTAGHEEYSAMRDQ targeted domains by a telomerase GV1001 peptide mimetic chemo-pharmacophores for the future induction of CTL responses

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Occam’s Quantum Strop: Synchronizing and Compressing Classical Cryptic in silico discovery of a novel identified Human testis-specific 12-mer YLP12 Sperm Peptide (SNR12-YLP12YLPVGGLRRIGG) Consensus17GHRGRRVGLGGGGRIGG) Sequence-based chemoanalogues Involved Processes via a Quantum Channel Gamete Genomic Integrity Effect in Immunocontraception

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico designed of an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization using a Quantum coupled mutation finder for predicting functionally or structurally important sites and quantum Jensen-Shannon divergence CUDA programming multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design in Preceding Membrane Neutralization using a Quantum coupled mutation finder for predicting functionally or structurally important sites and quantum Jensen-Shannon divergence CUDA programming multi-mimotopic algorithmic approach for biclustering analysis of expression data

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An algorithm Simulation of Quantum Dynamics Based on the Quantum Stochastic Differential Equation for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

CHARMM additive polarizable force fields for biophysics computer-aided drug design algorithms for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Circular Scale of Time and Energy of a Quantum State Calculated from the Schrödinger Perturbation Theory for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An algorithm estimation for CHARMM additive and polarizable force fields for biophysics and computer-aided drug design high-resolution refinement of high binding affinity inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution mimetic pharmacostructures antagonizing VEGFR-3-mediated oncogenic effects

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Distribution of quantum Fisher information in asymmetric cloning computational target fishing mining machinery as an identification tool for predicting therapeutic potential of GLP-1, INGAP-P and IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds based on chemogenomic databases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Distribution of a computational target fishing mining quantum Fisher information in asymmetric cloning machinery as an Identification tool for predicting therapeutic potential of GLP-1, INGAP-P and IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds based on chemogenomic databases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Process Model of Quantum Mechanics of Time and Energy of a Quantum State Calculated as an identification tool for predicting therapeutic potential of GLP-1, INGAP-P and IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds based on chemogenomic databases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Distribution of a computational target fishing mining quantum Fisher information in asymmetric cloning machinery as an Identification tool for predicting therapeutic potential of GLP-1, INGAP-P and IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds based on chemogenomic databases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Circular Scale of Time and Energy of a Quantum State Calculated from the Schrödinger Perturbation Theory as an identification tool for predicting therapeutic potential of GLP-1, INGAP-P and IGLHDPSHGTLPNGS peptide mimetic insulinotropic of high-potency compounds based on chemogenomic databases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A rational in silico drug-target flexibility complement methodology-design to Prepare Input Files for Fragment Based Quantum Chemical Calculations for the generation of a peptide-mimic novel pharmacoelement binding to the amino acid conserved sequences of the active loop Haemophilus influenzae porin P2

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A rational Tool to Prepare Input Files for Fragment Based Quantum Chemical Calculations for in silico drug-target flexibility complement methodology-design for the generation of a peptide-mimic novel pharmacoelement binding to the active loop of a Haemophilus influenzae porin P2 amino acid conserved sequences

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Tool to Rationally in silico Identification of a immunogenic MAGED4B peptide-mimetic Prepare Input Files for Fragment Based Quantum Chemical Calculations on pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An in silico annotated drug discovery interactive approach for Mining flexible-receptor docking experiments to select promising protein receptor snapshots on the depletion of tumor-associated macrophages by a computer-aided designed canditate druggable Toll-like receptor (Pam2IDG) peptide-domain targeted by a pharmacophoric mimetic agonistic agent

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Control aspects of quantum computing using pure and mixed states of a Computer-aided rational approach for the in silico generation of a TCR Peptide Mimetic Pharmacoligand as a potential chemo-modulator in Human Autoimmune Diseases

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A multi-mimotopic algorithmic approach for biclustering analysis of In silico designed expression data on an Anticancer Peptide SVS-1 multipharmacophore as a potential drug-like efficator in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico chemoproteomic prediction-scannings for the Quantum Dynamics in Continuum for Proton Transport I Basic Formulation of a tyrosinase aa95-104FMGFNCGNCK antigenic patternLFA-3/IgG fusion polypeptide IleAlaArgArgPheLeuOH (Kinetensin) mimetic pharmacophore on conserved Vitiligo post-trancripts domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Collapsing a Perfect Superposition to an in silico Anticancer Peptide SVS-1 multipharmacophore Chosen Quantum State without expression data Measurements of the potential multi-mimotopic algorithmic biclustering analysis of drug-like efficators in Preceding Membrane Neutralization

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico Identification of a Collapsing Perfect Superposition to a Chosen Quantum State without Measurements to a Rationally immunogenic MAGED4B peptide-mimetic pharmacophoric robust agent as a potential fragment-library derived drug-compound comprising vaccine mimic annotated properties in oral cancer immunotherapies

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico discovery of novel Quantum Clock Synchronization with a Single Qudit chemo-hyperstructure as a novel drug discovery dual targeting of the p53 and NF-κB pathways for the activation of the p53 tumor suppressor pathway by an engineered P44 cyclotidomimic agonisitic mechanistic pharmacoligand

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Quantum Navigation and Ranking Complex Networks for the in silico development of a unique fragment poly-pharmacologic modulator of CXCR4 tumor-derived heat-shock GGHFGPFDY peptide mimotopic complex-96 (HSPPC-96) by highthroughput identifying hits on the hydrophobic autotaxin/lysophospholipase D pocket

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

In silico rational Simulation of Quantum Dynamics Differential Equation Based on the Quantum Stochastic designed of a adenovirus library displaying random viral naive tropism replication-competent Oncolytic virus peptide-mimic pharmacophoric ligand supressor with potential therapeutic properties for pancreatic cancer

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A Finite-Size Universal Order Parameters and Quantum Phase computer simulated gp100 Peptide mimic Transitions on improved Algorithm for Chemically Tractable Semi-Automated Protein Inhibitor designed pharmacophore as a Vaccine-like and Interleukin-2 in silico generated superagonist with potential clinical effect in Patients with Advanced Melanoma

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

An Improved Computational Quantum-Behaved Particle Swarm Optimization Algorithm with Elitist Breeding for Unconstrained Optimization to Design an Epitope-Based Mimo-Peptidic hyper agonist consisting of linked active Pharmacophoric chemo-Scaffolds comprising in silico demonstrated vaccine-like potential properties against Saint Louis Encephalitis Virus conserved binding domains

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

A surface representation adaptive quantum computation in changing environments using projective IHMVYSK peptide-mimo based chemo-ligand simulation designed of therapeutic vaccine-like agonistic properties as a potential novel druggable synthetic regulator for future allergic and autoimmune treatment applications

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Distribution of quantum Ligand based prediction of a virion-attached pharmacophore cross-reacting asymmetric cloning synthetic Fisher information machines on EQHHRRTDN/GAAIGLAWIPYFGPAA peptide mimetic ligand modeling potential therapeutic properties against conserved conserved EBO16 over-expressed regions Ebola virus

Grigoriadis Ioannis, Grigoriadis George, Grigoriadis Nikolaos, George Galazios

Research Article – Cancer Stud Ther J

Molecular dynamics in silico drug discovery simulations from structure function relationships to a small-molecule PUMA targeted ACPP (ACPP-RGD) peptide mimotopic hyper-Inhibitory ligand pocket binding as a potent pharmacoregulator comprising potential mitigation activities of the radiation-Induced cell death

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Asymmetric bagging and feature selection for activities prediction of drug molecules of an in silico developed unique fragment poly-pharmacologic modulator of CXCR4 tumor-derived heat-shock GGHFGPFDY peptide mimotopic complex-96 (HSPPC-96) by highthroughput identifying hits in the hydrophobic autotaxin/lysophospholipase D pocket

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An integrated computational Mechanisms of Protein Allostery Simulations with Molecular Dynamics Revealing Atomic-Level approach on an in silico LWPQ designed multi-core super-agonist motif-like regulatory peptide for the activation of human stem cell transcripts

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Variational solvent-solute interface Quantum dynamics in continuum for proton transport in Silico generation of a sophisticated descriptor for the in silico identification and free energy evaluation of hybrid KPQRKTKRNT peptidomimetic leads as a potential inhibitor against helicase and HCV´sStructural NS3/4A protease regions

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Computer-aided CHARMM additive drug design and Orthodox Quantum Mechanics polarizable force fields for biophysics Success and Incoherence of an in silico KIF20A-derived Peptide agonistic mimicking sited designed poly-chemo-scaffold as an innovative drug-like molecule with potential clinical hyper-inhibitor properties in Gemcitabine treated Patients With Advanced Pancreatic Cancer

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Variational multiscale Success and Incoherence of Orthodox Quantum Mechanics models for charge transport CHARMM additive and polarizable force fields for biophysics and computer-aided drug design as an in silico KIF20A-derived Peptide agonistic mimicking sited and computer-aided designed poly-chemo-scaffold innovative drug-like molecule with potential clinical hyper-inhibitor properties in Patients With Advanced Pancreatic Cancer

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Multiscale geometric Lagrangian representation modeling of an in silico discovery of a Asn-Ile-Ile-Gly-Val-Ser-Tyr peptide mimetic high free energy recored chemical analog molecule CFTR targeted binding sites as a future mutant corrector against over-expressed cystic fibrosis pathological post-transcripts.

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A variational eigenvalue solver on a photonic quantum processor of algorithms for Large-Scale Protein-Ligand Docking experiments for the in silico prediction of a computer-aided molecular designed CTLA-4 blockador for the increasement of the antigen-specific CD8+ T-cells to the inprevaccinated patients with melanoma

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Can Von Neumann’s Quantum Computation Theory on Protein−Ligand Hyper drug-target Complexes interaction analysis for the in silico free energy potency optimization of a poly-targeted binding-pocket peptide mimic annotated chemo-antagonists to HIV-II viral replication cycle associated enzymes

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An annotated Neural-Network-Based NNScoring Function Characterization of Protein−Ligand Hyper drug-target Complexes interaction analysis for the in silico free energy potency optimization of a poly-targeted binding-pocket peptide mimic chemo-antagonists to HIV-II viral replication cycle associated enzymes

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Some Elucidations of the Theory on Revised Quantum Electrodynamic on Telomerase Peptide Vaccination simulated poly-chemo mimotopic pharmacological structure Combined with Temozolomide as a novel in silico promising anti-cancer drug-like agent in Stage IV Melanoma Patients for structural proteome-wide multi-targeted ligand-binding conserved binding pharmacophoric site comparison

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A for structural proteome-wide multi-targeted ligand-binding conserved binding pharmacophoric site comparison Quantum Attack Resistent Certificateless Multi Receiver Signcryption Scheme on Telomerase Peptide Vaccination simulated poly-chemo mimotopic pharmacological structure as a novel in silico promising anti-cancer drug-like agent in Stage IV Melanoma Patients

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A for structural proteome-wide multi-targeted ligand-binding conserved binding pharmacophoric site Quantum Attack Resistent Certificateless Multi Receiver Signcryption Scheme comparison with USNCTAM perspectives on mechanics in Telomerase Peptide Vaccination simulated poly-chemo mimotopic pharmacological structure as a novel in silico promising anti-cancer drug-like agent in Stage IV Melanoma Patients

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Universal Order substitution Parameters and Quantum Phase Transitions Finite-Size Approaches for high-resolution refinement and binding affinity estimated inhibitors targeted to the conserved CGQMCTVWCSSGC peptide mimetic pharmaco-structures with antagonizing VEGFR-3-mediated oncogenic effects.

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Can Hidden Variables Theories Meet Quantum Computation for high-resolution refinement and binding affinity estimation of inhibitors of CGQMCTVWCSSGC targeted conserved peptide substitution on mimetic pharmaco-structures with antagonizing VEGFR-3-mediated oncogenic effects?

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Quantum Theory of a Radiating Harmonically Multidimensional Scaling of a SMAR1-derived engineered P44 cyclotidomimic agonisitic novel chemo-hyperstructure as a dual targeted mechanistic pharmacoligand for the Stochastic Resonance and Synergetic activation of the NF-κB pathways and p53 tumor suppressor pathways

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Reaching New Levels of Realism in Modeling Biological hypermolecules on Glioma Growth Morphology generation of a MART-1 (26-35,27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) mimicking activator with a promising PF-3512676 and GM-CSF clinical outcome in metastatic melanoma

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Asymptomatic Distribution of on Glioma Growth Morphology for the generation of a Goodness-of-MART-1 (26-35,27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) mimicking Fit Tests in Logistic Regression Model activator with a promising PF-3512676 and GM-CSF clinical outcome in metastatic melanoma.

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Success and Incoherence of Orthodox Quantum Mechanics in silico KIF20A-derived Peptide agonistic drug molecules mimicking sited and computer-aided designed on a poly-chemo-scaffold as an innovative drug-like scaffolds comprising potential clinical hyper-inhibitor properties in Patients With Advanced Pancreatic Cancer when combined with Gemcitabine

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