DOI: 10.31038/MIP.2020111
Abstract
The number of colorectal cancer increases regularly every year in Algeria and precisely in Tlemcen. It is a disease involving several genetic, hormonal, professional, environmental, but also behavioral factors, namely nutrition, the objective is to evaluate the nutritional and lipid profile on the one hand and some oxidative parameters of And to determine the relationship that may exist between nutritional factors and oxidative stress in patients with this type of cancer.
Keywords
Oxidative Stress, Colorectal Cancer
Materials and Methods
Thirty-three patients with newly diagnosed colorectal cancer were recruited from the Department of Gastroenterology, C.H.U. (CL, HDL-LC, LDL-CL, TG) and the oxidative status (ORAC, Catalase, Vitamin C, MDA) of Tlemcen and thirty-five healthy controls.
Results
A very significant difference was observed for patients with liver cancer compared to ORAC controls (1, 143 ± 0.121) (0, 4197 ± 0.0456) p <0.000; MDA (0, 2400 ± 0.0492) (0, 083 ± 0.0275) P <0.008; Catalase (1.385 ± 0.162) (0, 588 ± 0.219) p <0.008; LDL-CHOL (0.4300 ± 0.0239) (1. 0692 ± 0.0627 p <0.000, on the other hand no difference was observed for Vitamin C (0.221 ± 0.0465) (0, 1947 ± 0.0889) p <0.615 HDL-CHOL (0.4300 ± 0.0322) (0.466 ± 0.031) p <0.355.
The balance of the oxidizing / antioxidant status is a primary factor in oncology. The free radicals can lead to the appearance of mutations and, conversely.
References
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