An improved quantum-behaved particle swarm optimization with elitist breeding (EB-QPSO) for unconstrained optimization is presented and empirically studied in this paper. In EB-QPSO, the novel elitist breeding strategy acts on the elitists of the swarm to escape from the likely local optima and guide the swarm to perform more efficient search. During the iterative optimization process of EB-QPSO, when criteria met, the personal best of each particle and the global best of the swarm are used to generate new diverse individuals through the transposon operators. The new generated individuals with better fitness are selected to be the new personal best particles and global best particle to guide the swarm for further solution exploration. A comprehensive simulation study is conducted on a set of twelve benchmark functions. Compared with five state-of-the-art quantum-behaved particle swarm optimization algorithms, the proposed EB-QPSO performs more competitively in all of the benchmark functions in terms of better global search capability and faster convergence rate. In this study, we present an Improved Quantum-Behaved Particle Swarm Optimization Algorithm with Elitist Breeding for Unconstrained Optimization Statistical Mechanics for Weak Measurements and Quantum Inseparability Novel procedure Computational Scaffolding on tumorigenic stem cell bacterial infected hybrids for the in silico rescaffolding and side-chain optimization on the neutrophil immune defense CAP37 protein.
Improved Quantum-Behaved; Particle Swarm; Optimization Algorithm; Elitist Breeding; Unconstrained Optimization;Statistical Mechanics; Weak Measurements; Quantum Inseparability;Novel procedure; Computational Scaffolding; tumorigenic stem cell bacterial; infected hybrids; silico rescaffolding; side-chain optimization; neutrophil immune defense; CAP37 protein;